TGTX vs. MIRM

Last updated Apr 2, 2026

Compare and contrast key facts about TG Therapeutics, Inc. (TGTX) and Mirum Pharmaceuticals, Inc. (MIRM).

Performance

TGTX vs. MIRM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in TG Therapeutics, Inc. (TGTX) and Mirum Pharmaceuticals, Inc. (MIRM). The values are adjusted to include any dividend payments, if applicable.

TGTX vs. MIRM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
TGTX TG Therapeutics, Inc.	12.65%	-0.96%	76.23%	44.38%	-37.74%	-63.48%	368.65%	39.27%
MIRM Mirum Pharmaceuticals, Inc.	19.79%	91.03%	40.07%	51.38%	22.26%	-8.65%	-28.79%	85.62%

Fundamentals

EPS TGTX : $2.77 MIRM : -$0.45
PS Ratio TGTX : 10.21 MIRM : 9.49
Total Revenue (TTM) TGTX : $531.90M MIRM : $521.31M
Gross Profit (TTM) TGTX : $453.87M MIRM : $493.34M
EBITDA (TTM) TGTX : $115.24M MIRM : $40.41M

Returns By Period

In the year-to-date period, TGTX achieves a 12.65% return, which is significantly lower than MIRM's 19.79% return.

TGTX

• 1D: 1.08%
• 1M: 14.22%
• YTD: 12.65%
• 6M: -8.15%
• 1Y: -11.05%
• 3Y*: 30.70%
• 5Y*: -7.26%
• 10Y*: 14.12%

MIRM

• 1D: 2.42%
• 1M: 5.03%
• YTD: 19.79%
• 6M: 29.62%
• 1Y: 114.85%
• 3Y*: 57.93%
• 5Y*: 35.65%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

TGTX vs. MIRM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TGTX

TGTX Risk / Return Rank: 30
TGTX Sharpe Ratio Rank: 30
TGTX Sortino Ratio Rank: 28
TGTX Omega Ratio Rank: 29
TGTX Calmar Ratio Rank: 30
TGTX Martin Ratio Rank: 32

MIRM

MIRM Risk / Return Rank: 93
MIRM Sharpe Ratio Rank: 94
MIRM Sortino Ratio Rank: 92
MIRM Omega Ratio Rank: 92
MIRM Calmar Ratio Rank: 94
MIRM Martin Ratio Rank: 93

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TGTX vs. MIRM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for TG Therapeutics, Inc. (TGTX) and Mirum Pharmaceuticals, Inc. (MIRM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TGTX	MIRM	Difference
Sharpe ratio Return per unit of total volatility	-0.24	2.66	-2.90
Sortino ratio Return per unit of downside risk	-0.02	3.14	-3.16
Omega ratio Gain probability vs. loss probability	1.00	1.44	-0.44
Calmar ratio Return relative to maximum drawdown	-0.35	5.35	-5.71
Martin ratio Return relative to average drawdown	-0.53	13.96	-14.49
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

TGTX vs. MIRM - Sharpe Ratio Comparison

The current TGTX Sharpe Ratio is -0.24, which is lower than the MIRM Sharpe Ratio of 2.66. The chart below compares the historical Sharpe Ratios of TGTX and MIRM, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	TGTX	MIRM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.24	2.66	-2.90
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.08	0.70	-0.78
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.16	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.05	0.46	-0.51

Correlation

The correlation between TGTX and MIRM is 0.27, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

TGTX vs. MIRM - Dividend Comparison

Neither TGTX nor MIRM has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

TGTX vs. MIRM - Drawdown Comparison

The maximum TGTX drawdown since its inception was -99.52%, which is greater than MIRM's maximum drawdown of -63.78%. Use the drawdown chart below to compare losses from any high point for TGTX and MIRM.

Drawdown Indicators

	TGTX	MIRM	Difference
Max Drawdown Largest peak-to-trough decline	-99.52%	-63.78%	-35.74%
Max Drawdown (1Y) Largest decline over 1 year	-42.01%	-20.55%	-21.46%
Max Drawdown (5Y) Largest decline over 5 years	-92.36%	-40.25%	-52.11%
Max Drawdown (10Y) Largest decline over 10 years	-93.19%	—	—
Current Drawdown Current decline from peak	-85.61%	-12.89%	-72.72%
Average Drawdown Average peak-to-trough decline	-91.55%	-20.53%	-71.02%
Ulcer Index Depth and duration of drawdowns from previous peaks	28.02%	7.88%	+20.14%

Volatility

TGTX vs. MIRM - Volatility Comparison

TG Therapeutics, Inc. (TGTX) has a higher volatility of 15.01% compared to Mirum Pharmaceuticals, Inc. (MIRM) at 14.02%. This indicates that TGTX's price experiences larger fluctuations and is considered to be riskier than MIRM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TGTX	MIRM	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.01%	14.02%	+0.99%
Volatility (6M) Calculated over the trailing 6-month period	28.15%	32.60%	-4.45%
Volatility (1Y) Calculated over the trailing 1-year period	46.37%	43.49%	+2.88%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	87.52%	51.47%	+36.05%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	86.93%	74.62%	+12.31%

Financials