RYTM vs. LEU
RYTM (Rhythm Pharmaceuticals, Inc.) and LEU (Centrus Energy Corp.) are both stocks. RYTM operates in Biotechnology (Healthcare), while LEU operates in Uranium (Energy). Over the past 5 years, RYTM returned 35.24%/yr vs 44.90%/yr for LEU. At a 0.16 correlation, their price movements are largely independent.
Performance
RYTM vs. LEU - Performance Comparison
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Returns By Period
In the year-to-date period, RYTM achieves a -19.73% return, which is significantly higher than LEU's -32.55% return.
RYTM
- 1D
- -0.55%
- 1M
- -8.76%
- YTD
- -19.73%
- 6M
- -18.31%
- 1Y
- 26.16%
- 3Y*
- 70.19%
- 5Y*
- 35.24%
- 10Y*
- —
LEU
- 1D
- 1.21%
- 1M
- -21.02%
- YTD
- -32.55%
- 6M
- -39.02%
- 1Y
- 14.42%
- 3Y*
- 71.98%
- 5Y*
- 44.90%
- 10Y*
- 46.90%
RYTM vs. LEU - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
RYTM Rhythm Pharmaceuticals, Inc. | -19.73% | 91.21% | 21.78% | 57.86% | 191.78% | -66.43% | 29.49% | -14.58% | -7.50% | 25.20% |
LEU Centrus Energy Corp. | -32.55% | 264.45% | 22.42% | 67.52% | -34.92% | 115.78% | 236.19% | 307.10% | -57.86% | 12.32% |
Correlation
The correlation between RYTM and LEU is 0.18, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.18 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.19 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.20 |
Correlation (All Time) Calculated using the full available price history since Oct 5, 2017 | 0.16 |
Fundamentals
RYTM:
$5.84B
LEU:
$3.68B
RYTM:
-$3.10
LEU:
$2.89
RYTM:
26.00
LEU:
7.58
RYTM:
712.63
LEU:
4.74
RYTM:
$217.17M
LEU:
$452.30M
RYTM:
$194.16M
LEU:
$116.10M
RYTM:
-$182.86M
LEU:
$70.50M
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Return for Risk
RYTM vs. LEU — Risk / Return Rank
RYTM
LEU
RYTM vs. LEU - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Rhythm Pharmaceuticals, Inc. (RYTM) and Centrus Energy Corp. (LEU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| RYTM | LEU | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.30 | ||
| Sortino ratioReturn per unit of downside risk | +0.40 | ||
| Omega ratioGain probability vs. loss probability | 1.15 | 1.11 | +0.04 |
| Calmar ratioReturn relative to maximum drawdown | 0.74 | 0.23 | +0.51 |
| Martin ratioReturn relative to average drawdown | 1.74 | 0.38 | +1.36 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| RYTM | LEU | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.46 | 0.16 | +0.30 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.46 | 0.52 | -0.06 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.57 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.18 | -0.10 | +0.28 |
Drawdowns
RYTM vs. LEU - Drawdown Comparison
The maximum RYTM drawdown since its inception was -92.10%, smaller than the maximum LEU drawdown of -99.98%. Use the drawdown chart below to compare losses from any high point for RYTM and LEU.
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Drawdown Indicators
| RYTM | LEU | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -92.10% | -99.98% | +7.88% |
Max Drawdown (1Y)Largest decline over 1 year | -35.54% | -62.89% | +27.35% |
Max Drawdown (3Y)Largest decline over 3 years | -35.54% | -62.89% | +27.35% |
Max Drawdown (5Y)Largest decline over 5 years | -85.49% | -78.23% | -7.26% |
Max Drawdown (10Y)Largest decline over 10 years | — | -83.84% | — |
Current DrawdownCurrent decline from peak | -26.95% | -97.58% | +70.63% |
Average DrawdownAverage peak-to-trough decline | -32.18% | -73.98% | +41.80% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 15.08% | 37.75% | -22.67% |
Volatility
RYTM vs. LEU - Volatility Comparison
The current volatility for Rhythm Pharmaceuticals, Inc. (RYTM) is 14.47%, while Centrus Energy Corp. (LEU) has a volatility of 22.37%. This indicates that RYTM experiences smaller price fluctuations and is considered to be less risky than LEU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| RYTM | LEU | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 14.47% | 22.37% | -7.90% |
Volatility (6M)Calculated over the trailing 6-month period | 36.66% | 65.68% | -29.02% |
Volatility (1Y)Calculated over the trailing 1-year period | 57.36% | 91.10% | -33.74% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 76.40% | 86.24% | -9.84% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 70.96% | 82.26% | -11.30% |
Dividends
RYTM vs. LEU - Dividend Comparison
Neither RYTM nor LEU has paid dividends to shareholders.
Financials
RYTM vs. LEU - Financials Comparison
This section allows you to compare key financial metrics between Rhythm Pharmaceuticals, Inc. and Centrus Energy Corp.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
RYTM vs. LEU - Profitability Comparison
RYTM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Rhythm Pharmaceuticals, Inc. reported a gross profit of 52.96M and revenue of 60.11M. Therefore, the gross margin over that period was 88.1%.
LEU - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Centrus Energy Corp. reported a gross profit of 31.50M and revenue of 76.70M. Therefore, the gross margin over that period was 41.1%.
RYTM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Rhythm Pharmaceuticals, Inc. reported an operating income of -52.36M and revenue of 60.11M, resulting in an operating margin of -87.1%.
LEU - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Centrus Energy Corp. reported an operating income of 800.00K and revenue of 76.70M, resulting in an operating margin of 1.0%.
RYTM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Rhythm Pharmaceuticals, Inc. reported a net income of -56.74M and revenue of 60.11M, resulting in a net margin of -94.4%.
LEU - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Centrus Energy Corp. reported a net income of 10.00M and revenue of 76.70M, resulting in a net margin of 13.0%.
Frequently Asked Questions
RYTM and LEU have a correlation of 0.18, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
LEU has higher volatility (22.37%) compared to RYTM (14.47%). In terms of maximum drawdown, RYTM dropped -92.10% vs LEU's -99.98%.
RYTM currently has the higher Sharpe Ratio (0.46 vs 0.16), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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