OTPIX vs. GTLLX

Last updated Aug 6, 2026

OTPIX (ProFunds NASDAQ-100 Fund) and GTLLX (Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio) are both Large Cap Growth Equities funds. Over the past 10 years, OTPIX returned 4.83%/yr vs 16.67%/yr for GTLLX. Their correlation of 0.89 means they have usually moved in the same direction. OTPIX charges 1.48%/yr vs 0.85%/yr for GTLLX.

Performance

OTPIX vs. GTLLX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ProFunds NASDAQ-100 Fund (OTPIX) and Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio (GTLLX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, OTPIX achieves a 16.78% return, which is significantly lower than GTLLX's 27.13% return. Over the past 10 years, OTPIX has underperformed GTLLX with an annualized return of 4.83%, while GTLLX has yielded a comparatively higher 16.67% annualized return.

OTPIX

• 1D: 3.34%
• 1M: -0.02%
• 6M: 18.62%
• YTD: 16.78%
• 1Y: 27.45%
• 3Y*: -22.48%
• 5Y*: -11.62%
• 10Y*: 4.83%
• ALL TIME*: 5.74%

GTLLX

• 1D: 3.14%
• 1M: 3.61%
• 6M: 30.03%
• YTD: 27.13%
• 1Y: 38.58%
• 3Y*: 25.68%
• 5Y*: 14.21%
• 10Y*: 16.67%
• ALL TIME*: 12.70%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
GTLLX Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio	$0.00	$0.00	$0.00
OTPIX ProFunds NASDAQ-100 Fund	$0.00	$0.00	$0.00

OTPIX vs. GTLLX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
OTPIX ProFunds NASDAQ-100 Fund	16.78%	18.08%	-69.20%	51.66%	-34.36%	48.75%	45.00%	36.58%	-1.75%	29.45%
GTLLX Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio	27.13%	17.44%	20.71%	27.10%	-21.69%	32.91%	18.80%	34.86%	-5.23%	27.83%

Correlation

The correlation between OTPIX and GTLLX is 0.88, meaning they have usually moved in the same direction, including during past declines.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.88
Correlation (3Y) Balances recent behavior with more history.	0.88
Correlation (5Y) Shows whether the relationship held over a longer period.	0.90
Correlation (10Y) Provides a long-term view across more market conditions.	0.89
Correlation (All Time) Calculated using the full available price history since Jan 3, 2005	0.89

The correlation between OTPIX and GTLLX has been stable across timeframes, ranging from 0.88 to 0.90 - a consistent structural relationship.

Return for Risk

OTPIX vs. GTLLX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

OTPIX

OTPIX Risk / Return Rank: 38
OTPIX Sharpe Ratio Rank: 36
OTPIX Sortino Ratio Rank: 35
OTPIX Omega Ratio Rank: 33
OTPIX Calmar Ratio Rank: 48
OTPIX Martin Ratio Rank: 40

GTLLX

GTLLX Risk / Return Rank: 77
GTLLX Sharpe Ratio Rank: 78
GTLLX Sortino Ratio Rank: 73
GTLLX Omega Ratio Rank: 61
GTLLX Calmar Ratio Rank: 87
GTLLX Martin Ratio Rank: 88

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

OTPIX vs. GTLLX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ProFunds NASDAQ-100 Fund (OTPIX) and Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio (GTLLX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	OTPIX	GTLLX	Difference
Sharpe ratio: Return per unit of total volatility	1.37	1.99	-0.62
Sortino ratio: Return per unit of downside risk	1.92	2.72	-0.81
Omega ratio: Gain probability vs. loss probability	1.24	1.33	-0.09
Calmar ratio: Return relative to maximum drawdown	2.13	3.50	-1.37
Martin ratio: Return relative to average drawdown	6.68	12.98	-6.30

OTPIX vs. GTLLX - Sharpe Ratio Comparison

The current OTPIX Sharpe Ratio is 1.37, which is lower than the GTLLX Sharpe Ratio of 1.99. The chart below compares the historical Sharpe Ratios of OTPIX and GTLLX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

OTPIX vs. GTLLX - Drawdown Comparison

The maximum OTPIX drawdown since its inception was -79.55%, which is greater than GTLLX's maximum drawdown of -54.32%. Use the drawdown chart below to compare losses from any high point for OTPIX and GTLLX.

Drawdown Indicators

	OTPIX	GTLLX	Difference
Max Drawdown Largest peak-to-trough decline	-79.55%	-54.32%	-25.23%
Max Drawdown (1Y) Largest decline over 1 year	-12.53%	-10.76%	-1.77%
Max Drawdown (3Y) Largest decline over 3 years	-79.55%	-41.54%	-38.01%
Max Drawdown (5Y) Largest decline over 5 years	-79.55%	-41.54%	-38.01%
Max Drawdown (10Y) Largest decline over 10 years	-79.55%	-41.54%	-38.01%
Current Drawdown Current decline from peak	-65.20%	0.00%	-65.20%
Average Drawdown Average peak-to-trough decline	-23.08%	-8.53%	-14.55%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.98%	2.88%	+1.10%

Volatility

OTPIX vs. GTLLX - Volatility Comparison

ProFunds NASDAQ-100 Fund (OTPIX) has a higher volatility of 7.62% compared to Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio (GTLLX) at 5.91%. This indicates that OTPIX's price experiences larger fluctuations and is considered to be riskier than GTLLX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OTPIX	GTLLX	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.62%	5.91%	+1.71%
Volatility (6M) Calculated over the trailing 6-month period	16.29%	15.58%	+0.71%
Volatility (1Y) Calculated over the trailing 1-year period	19.56%	19.03%	+0.53%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	42.06%	29.27%	+12.79%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	33.38%	25.13%	+8.25%

OTPIX vs. GTLLX - Expense Ratio Comparison

OTPIX has a 1.48% expense ratio, which is higher than GTLLX's 0.85% expense ratio.

Dividends

OTPIX vs. GTLLX - Dividend Comparison

OTPIX's dividend yield for the trailing twelve months is around 1.48%, less than GTLLX's 12.06% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
GTLLX Glenmede Quantitative U.S. Large Cap Growth Equity Portfolio	12.06%	15.33%	40.42%	4.91%	7.93%	20.20%	15.12%	14.10%	16.97%	2.29%	0.58%	0.61%
OTPIX ProFunds NASDAQ-100 Fund	1.48%	1.72%	0.76%	0.00%	0.00%	18.31%	1.10%	0.87%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both OTPIX and GTLLX in my portfolio?

OTPIX and GTLLX have a correlation of 0.88, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, OTPIX or GTLLX?

OTPIX has higher volatility (7.62%) compared to GTLLX (5.91%). In terms of maximum drawdown, OTPIX dropped -79.55% vs GTLLX's -54.32%.

Which has better risk-adjusted returns?

GTLLX currently has the higher Sharpe Ratio (1.99 vs 1.37), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.