OMER vs. ARCT

Last updated Jun 9, 2026

OMER (Omeros Corporation) and ARCT (Arcturus Therapeutics Holdings Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, OMER returned -9.29%/yr vs -26.90%/yr for ARCT. At a 0.34 correlation, their price movements are largely independent.

Performance

OMER vs. ARCT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Omeros Corporation (OMER) and Arcturus Therapeutics Holdings Inc. (ARCT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, OMER achieves a -42.65% return, which is significantly lower than ARCT's 16.15% return.

OMER

• 1D: 0.61%
• 1M: -30.29%
• YTD: -42.65%
• 6M: -13.60%
• 1Y: 161.27%
• 3Y*: 9.51%
• 5Y*: -9.29%
• 10Y*: -0.87%

ARCT

• 1D: -2.47%
• 1M: -22.78%
• YTD: 16.15%
• 6M: -4.43%
• 1Y: -44.33%
• 3Y*: -36.26%
• 5Y*: -26.90%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

OMER vs. ARCT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
OMER Omeros Corporation	-42.65%	73.84%	202.14%	44.69%	-64.85%	-54.99%	1.38%
ARCT Arcturus Therapeutics Holdings Inc.	16.15%	-63.88%	-46.18%	85.91%	-54.17%	-14.68%	155.18%

Correlation

The correlation between OMER and ARCT is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.22
Correlation (3Y) Calculated over the trailing 3-year period	0.30
Correlation (5Y) Calculated over the trailing 5-year period	0.36
Correlation (All Time) Calculated using the full available price history since Apr 17, 2020	0.34

The correlation between OMER and ARCT shifts across timeframes, from 0.22 (1 year) to 0.36 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap OMER : $625.58M ARCT : $202.36M
EPS OMER : -$0.05 ARCT : -$1.81
Total Revenue (TTM) OMER : $0.00 ARCT : $46.80M
Gross Profit (TTM) OMER : -$10.29M ARCT : $40.72M
EBITDA (TTM) OMER : -$110.44M ARCT : -$84.61M

Return for Risk

OMER vs. ARCT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OMER

OMER Risk / Return Rank: 86
OMER Sharpe Ratio Rank: 70
OMER Sortino Ratio Rank: 96
OMER Omega Ratio Rank: 92
OMER Calmar Ratio Rank: 88
OMER Martin Ratio Rank: 82

ARCT

ARCT Risk / Return Rank: 25
ARCT Sharpe Ratio Rank: 21
ARCT Sortino Ratio Rank: 28
ARCT Omega Ratio Rank: 27
ARCT Calmar Ratio Rank: 21
ARCT Martin Ratio Rank: 26

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OMER vs. ARCT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Omeros Corporation (OMER) and Arcturus Therapeutics Holdings Inc. (ARCT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	OMER	ARCT	Difference
Sharpe ratio: Return per unit of total volatility	0.87	-0.48	+1.35
Sortino ratio: Return per unit of downside risk	4.14	-0.15	+4.30
Omega ratio: Gain probability vs. loss probability	1.47	0.98	+0.49
Calmar ratio: Return relative to maximum drawdown	3.77	-0.60	+4.37
Martin ratio: Return relative to average drawdown	7.05	-0.83	+7.88
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

OMER vs. ARCT - Sharpe Ratio Comparison

The current OMER Sharpe Ratio is 0.87, which is higher than the ARCT Sharpe Ratio of -0.48. The chart below compares the historical Sharpe Ratios of OMER and ARCT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	OMER	ARCT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.87	-0.48	+1.35
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.07	-0.29	+0.22
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.01	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.01	-0.13	+0.14

Drawdowns

OMER vs. ARCT - Drawdown Comparison

The maximum OMER drawdown since its inception was -95.95%, roughly equal to the maximum ARCT drawdown of -95.23%. Use the drawdown chart below to compare losses from any high point for OMER and ARCT.

Drawdown Indicators

	OMER	ARCT	Difference
Max Drawdown Largest peak-to-trough decline	-95.95%	-95.23%	-0.72%
Max Drawdown (1Y) Largest decline over 1 year	-43.00%	-74.53%	+31.53%
Max Drawdown (3Y) Largest decline over 3 years	-85.60%	-86.71%	+1.11%
Max Drawdown (5Y) Largest decline over 5 years	-93.37%	-89.87%	-3.50%
Max Drawdown (10Y) Largest decline over 10 years	-95.95%	—	—
Current Drawdown Current decline from peak	-63.09%	-94.24%	+31.15%
Average Drawdown Average peak-to-trough decline	-48.45%	-73.02%	+24.57%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.99%	53.28%	-30.29%

Volatility

OMER vs. ARCT - Volatility Comparison

The current volatility for Omeros Corporation (OMER) is 15.62%, while Arcturus Therapeutics Holdings Inc. (ARCT) has a volatility of 19.67%. This indicates that OMER experiences smaller price fluctuations and is considered to be less risky than ARCT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OMER	ARCT	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.62%	19.67%	-4.05%
Volatility (6M) Calculated over the trailing 6-month period	72.52%	41.10%	+31.42%
Volatility (1Y) Calculated over the trailing 1-year period	186.97%	92.73%	+94.24%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	134.66%	91.85%	+42.81%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	110.86%	102.23%	+8.63%

Dividends

OMER vs. ARCT - Dividend Comparison

Neither OMER nor ARCT has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both OMER and ARCT in my portfolio?

OMER and ARCT have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, OMER or ARCT?

ARCT has higher volatility (19.67%) compared to OMER (15.62%). In terms of maximum drawdown, OMER dropped -95.95% vs ARCT's -95.23%.

Which has better risk-adjusted returns?

OMER currently has the higher Sharpe Ratio (0.87 vs -0.48), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.