Omeros Corporation (OMER)

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Omeros Corporation (OMER) is down 39.9% since the beginning of the year. At $10 per share, OMER is trading 41.5% below its 52-week high of $18. Investors who bought $1,000 worth of OMER shares 5 years ago would now be looking at an investment worth $668.

Omeros Corporation (OMER) has returned -39.85% so far this year and 221.81% over the past 12 months. Over the last ten years, OMER has returned 0.05% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.

Based on dividend-adjusted daily data since Oct 8, 2009, OMER's average daily return is +0.17%, while the average monthly return is +3.20%. At this rate, an investment would double in approximately 1.8 years.

Historically, 44% of months were positive and 56% were negative. The best month was Nov 2024 with a return of +180.9%, while the worst month was Oct 2023 at -59.3%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 7 months.

On a daily basis, OMER closed higher 47% of trading days. The best single day was Oct 15, 2025 with a return of +154.2%, while the worst single day was Oct 1, 2018 at -42.8%.

Omeros Corporation has an annualized alpha of 31.14%, beta of 1.23, and R2 of 0.05 versus S&P 500 Index. Calculated based on daily prices since October 08, 2009.

• This stock participated in 163.52% of S&P 500 Index downside but only 114.65% of its upside - more exposed to losses than it benefited from rallies.
• R2 of 0.05 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

OMER ranks 89 for risk / return — in the top 89% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Omeros Corporation. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Omeros Corporation was 95.95%, occurring on Oct 27, 2023. The portfolio has not yet recovered.

The current Omeros Corporation drawdown is 61.30%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Omeros Corporation over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Omeros Corporation is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.