NTSD vs. PILL

Last updated Jun 24, 2026

NTSD (WisdomTree Efficient U.S. Plus International Equity Fund) and PILL (Direxion Daily Pharmaceutical & Medical Bull 3X Shares) are both Leveraged Equities funds. NTSD is actively managed, while PILL is passively managed. A 0.51 correlation means they provide meaningful diversification when combined. NTSD charges 0.35%/yr vs 0.98%/yr for PILL.

Performance

NTSD vs. PILL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree Efficient U.S. Plus International Equity Fund (NTSD) and Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

NTSD

• 1D: -2.11%
• 1M: -0.58%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

PILL

• 1D: 5.13%
• 1M: 27.73%
• YTD: 26.72%
• 6M: 23.80%
• 1Y: 194.90%
• 3Y*: 24.44%
• 5Y*: -7.89%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

NTSD vs. PILL - Yearly Performance Comparison

	2026 (YTD)
NTSD WisdomTree Efficient U.S. Plus International Equity Fund	15.69%
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares	56.96%

Correlation

The correlation between NTSD and PILL is 0.51, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (All Time) Calculated using the full available price history since Mar 19, 2026	0.51

Return for Risk

NTSD vs. PILL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NTSD

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

PILL

PILL Risk / Return Rank: 86
PILL Sharpe Ratio Rank: 93
PILL Sortino Ratio Rank: 80
PILL Omega Ratio Rank: 72
PILL Calmar Ratio Rank: 92
PILL Martin Ratio Rank: 90

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NTSD vs. PILL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree Efficient U.S. Plus International Equity Fund (NTSD) and Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	NTSD	PILL	Difference
Sharpe ratio: Return per unit of total volatility	—	3.14	—
Sortino ratio: Return per unit of downside risk	—	3.27	—
Omega ratio: Gain probability vs. loss probability	—	1.40	—
Calmar ratio: Return relative to maximum drawdown	—	5.91	—
Martin ratio: Return relative to average drawdown	—	19.45	—

Drawdowns

NTSD vs. PILL - Drawdown Comparison

The maximum NTSD drawdown since its inception was -5.58%, smaller than the maximum PILL drawdown of -88.76%. Use the drawdown chart below to compare losses from any high point for NTSD and PILL.

Drawdown Indicators

	NTSD	PILL	Difference
Max Drawdown Largest peak-to-trough decline	-5.58%	-88.76%	+83.18%
Max Drawdown (1Y) Largest decline over 1 year	—	-33.21%	—
Max Drawdown (3Y) Largest decline over 3 years	—	-60.43%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-83.26%	—
Current Drawdown Current decline from peak	-2.97%	-56.58%	+53.61%
Average Drawdown Average peak-to-trough decline	-1.09%	-58.54%	+57.45%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	10.07%	—

Volatility

Volatility by Period

	NTSD	PILL	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	18.07%	—
Volatility (6M) Calculated over the trailing 6-month period	—	48.23%	—
Volatility (1Y) Calculated over the trailing 1-year period	25.11%	62.55%	-37.44%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.11%	60.62%	-35.51%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.11%	63.79%	-38.68%

NTSD vs. PILL - Expense Ratio Comparison

NTSD has a 0.35% expense ratio, which is lower than PILL's 0.98% expense ratio.

Dividends

NTSD vs. PILL - Dividend Comparison

NTSD has not paid dividends to shareholders, while PILL's dividend yield for the trailing twelve months is around 0.49%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
NTSD WisdomTree Efficient U.S. Plus International Equity Fund	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares	0.49%	0.69%	1.28%	1.83%	0.67%	0.00%	0.00%	0.38%	0.91%	0.10%

Frequently Asked Questions

Can I hold both NTSD and PILL in my portfolio?

NTSD and PILL have a correlation of 0.51, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, NTSD or PILL?

On fees, NTSD is cheaper at 0.35% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, NTSD or PILL?

NTSD is cheaper with a 0.35% expense ratio, compared with 0.98% for PILL.

Which ETF pays a higher dividend yield, NTSD or PILL?

PILL has the higher dividend yield at 0.49%, compared with 0.00% for NTSD.

What is the main difference between NTSD and PILL?

They also come from different issuers: WisdomTree and Direxion. Their fees differ too: 0.35% for NTSD and 0.98% for PILL.