NTRA vs. PVLA
NTRA (Natera, Inc.) and PVLA (Palvella Therapeutics, Inc) are both stocks. Both are in the Healthcare sector — NTRA in Diagnostics & Research, PVLA in Biotechnology. Over the past year, NTRA returned 37.79% vs 426.53% for PVLA. At a 0.17 correlation, their price movements are largely independent.
Performance
NTRA vs. PVLA - Performance Comparison
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Returns By Period
In the year-to-date period, NTRA achieves a 2.48% return, which is significantly lower than PVLA's 13.38% return.
NTRA
- 1D
- 2.60%
- 1M
- 15.54%
- YTD
- 2.48%
- 6M
- -0.27%
- 1Y
- 37.79%
- 3Y*
- 65.95%
- 5Y*
- 14.42%
- 10Y*
- 33.08%
PVLA
- 1D
- -0.13%
- 1M
- 4.11%
- YTD
- 13.38%
- 6M
- 18.36%
- 1Y
- 426.53%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
NTRA vs. PVLA - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | |
|---|---|---|---|
NTRA Natera, Inc. | 2.48% | 44.72% | -4.95% |
PVLA Palvella Therapeutics, Inc | 13.38% | 772.25% | -8.27% |
Correlation
The correlation between NTRA and PVLA is 0.23, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.23 |
Correlation (All Time) Calculated using the full available price history since Dec 16, 2024 | 0.17 |
Fundamentals
NTRA:
$33.22B
PVLA:
$1.34B
NTRA:
-$1.64
PVLA:
-$3.75
NTRA:
18.73
PVLA:
47.72
NTRA:
$2.50B
PVLA:
$0.00
NTRA:
$1.63B
PVLA:
$0.00
NTRA:
-$294.86M
PVLA:
-$14.75M
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Return for Risk
NTRA vs. PVLA — Risk / Return Rank
NTRA
PVLA
NTRA vs. PVLA - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Natera, Inc. (NTRA) and Palvella Therapeutics, Inc (PVLA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NTRA | PVLA | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -4.44 | ||
| Sortino ratioReturn per unit of downside risk | -3.10 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.54 | -0.36 |
| Calmar ratioReturn relative to maximum drawdown | 1.35 | 13.82 | -12.48 |
| Martin ratioReturn relative to average drawdown | 2.80 | 31.14 | -28.34 |
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Drawdowns
NTRA vs. PVLA - Drawdown Comparison
The maximum NTRA drawdown since its inception was -77.74%, which is greater than PVLA's maximum drawdown of -31.48%. Use the drawdown chart below to compare losses from any high point for NTRA and PVLA.
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Drawdown Indicators
| NTRA | PVLA | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -77.74% | -31.48% | -46.26% |
Max Drawdown (1Y)Largest decline over 1 year | -28.20% | -31.11% | +2.91% |
Max Drawdown (3Y)Largest decline over 3 years | -39.94% | — | — |
Max Drawdown (5Y)Largest decline over 5 years | -77.74% | — | — |
Max Drawdown (10Y)Largest decline over 10 years | -77.74% | — | — |
Current DrawdownCurrent decline from peak | -7.72% | -19.99% | +12.27% |
Average DrawdownAverage peak-to-trough decline | -33.38% | -11.16% | -22.22% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.52% | 13.79% | -0.27% |
Volatility
NTRA vs. PVLA - Volatility Comparison
The current volatility for Natera, Inc. (NTRA) is 12.58%, while Palvella Therapeutics, Inc (PVLA) has a volatility of 19.68%. This indicates that NTRA experiences smaller price fluctuations and is considered to be less risky than PVLA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NTRA | PVLA | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 12.58% | 19.68% | -7.10% |
Volatility (6M)Calculated over the trailing 6-month period | 35.53% | 61.91% | -26.38% |
Volatility (1Y)Calculated over the trailing 1-year period | 43.14% | 80.85% | -37.71% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 57.02% | 82.11% | -25.09% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 60.82% | 82.11% | -21.29% |
Dividends
NTRA vs. PVLA - Dividend Comparison
Neither NTRA nor PVLA has paid dividends to shareholders.
Financials
NTRA vs. PVLA - Financials Comparison
This section allows you to compare key financial metrics between Natera, Inc. and Palvella Therapeutics, Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
NTRA and PVLA have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
PVLA has higher volatility (19.68%) compared to NTRA (12.58%). In terms of maximum drawdown, NTRA dropped -77.74% vs PVLA's -31.48%.
PVLA currently has the higher Sharpe Ratio (5.32 vs 0.88), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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