NTRA vs. IBKR

Last updated Jun 13, 2026

NTRA (Natera, Inc.) and IBKR (Interactive Brokers Group, Inc.) are both stocks. NTRA operates in Diagnostics & Research (Healthcare), while IBKR operates in Capital Markets (Financial Services). Over the past 10 years, NTRA returned 33.53%/yr vs 26.54%/yr for IBKR. At a 0.30 correlation, their price movements are largely independent.

Performance

NTRA vs. IBKR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Natera, Inc. (NTRA) and Interactive Brokers Group, Inc. (IBKR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, NTRA achieves a -7.43% return, which is significantly lower than IBKR's 41.50% return. Over the past 10 years, NTRA has outperformed IBKR with an annualized return of 33.53%, while IBKR has yielded a comparatively lower 26.54% annualized return.

NTRA

• 1D: -3.27%
• 1M: 8.58%
• YTD: -7.43%
• 6M: -8.57%
• 1Y: 29.04%
• 3Y*: 61.10%
• 5Y*: 15.34%
• 10Y*: 33.53%

IBKR

• 1D: 2.23%
• 1M: 6.79%
• YTD: 41.50%
• 6M: 41.85%
• 1Y: 78.02%
• 3Y*: 67.33%
• 5Y*: 41.64%
• 10Y*: 26.54%

*Multi-year figures are annualized to reflect compound growth (CAGR)

NTRA vs. IBKR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
NTRA Natera, Inc.	-7.43%	44.72%	152.71%	55.94%	-56.99%	-6.16%	195.40%	141.33%	55.28%	-23.23%
IBKR Interactive Brokers Group, Inc.	41.50%	46.37%	114.43%	15.14%	-8.35%	31.12%	31.71%	-14.01%	-7.13%	63.75%

Correlation

The correlation between NTRA and IBKR is 0.32, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.32
Correlation (3Y) Calculated over the trailing 3-year period	0.30
Correlation (5Y) Calculated over the trailing 5-year period	0.33
Correlation (10Y) Calculated over the trailing 10-year period	0.31
Correlation (All Time) Calculated using the full available price history since Jul 2, 2015	0.30

Fundamentals

Market Cap NTRA : $30.01B IBKR : $40.72B
EPS NTRA : -$1.64 IBKR : $3.76
PS Ratio NTRA : 11.70 IBKR : 4.66
PB Ratio NTRA : 16.92 IBKR : 1.92
Total Revenue (TTM) NTRA : $2.50B IBKR : $8.69B
Gross Profit (TTM) NTRA : $1.63B IBKR : $7.75B
EBITDA (TTM) NTRA : -$294.86M IBKR : $7.07B

Return for Risk

NTRA vs. IBKR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NTRA

NTRA Risk / Return Rank: 62
NTRA Sharpe Ratio Rank: 65
NTRA Sortino Ratio Rank: 60
NTRA Omega Ratio Rank: 59
NTRA Calmar Ratio Rank: 64
NTRA Martin Ratio Rank: 63

IBKR

IBKR Risk / Return Rank: 88
IBKR Sharpe Ratio Rank: 90
IBKR Sortino Ratio Rank: 86
IBKR Omega Ratio Rank: 84
IBKR Calmar Ratio Rank: 90
IBKR Martin Ratio Rank: 89

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NTRA vs. IBKR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Natera, Inc. (NTRA) and Interactive Brokers Group, Inc. (IBKR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	NTRA	IBKR	Difference
Sharpe ratio: Return per unit of total volatility	0.68	2.08	-1.40
Sortino ratio: Return per unit of downside risk	1.15	2.67	-1.52
Omega ratio: Gain probability vs. loss probability	1.14	1.33	-0.18
Calmar ratio: Return relative to maximum drawdown	1.03	4.20	-3.16
Martin ratio: Return relative to average drawdown	2.17	10.65	-8.48

NTRA vs. IBKR - Sharpe Ratio Comparison

The current NTRA Sharpe Ratio is 0.68, which is lower than the IBKR Sharpe Ratio of 2.08. The chart below compares the historical Sharpe Ratios of NTRA and IBKR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

NTRA vs. IBKR - Drawdown Comparison

The maximum NTRA drawdown since its inception was -77.74%, which is greater than IBKR's maximum drawdown of -63.66%. Use the drawdown chart below to compare losses from any high point for NTRA and IBKR.

Drawdown Indicators

	NTRA	IBKR	Difference
Max Drawdown Largest peak-to-trough decline	-77.74%	-63.66%	-14.08%
Max Drawdown (1Y) Largest decline over 1 year	-28.20%	-18.70%	-9.50%
Max Drawdown (3Y) Largest decline over 3 years	-39.94%	-38.66%	-1.28%
Max Drawdown (5Y) Largest decline over 5 years	-77.74%	-38.66%	-39.08%
Max Drawdown (10Y) Largest decline over 10 years	-77.74%	-55.09%	-22.65%
Current Drawdown Current decline from peak	-16.64%	0.00%	-16.64%
Average Drawdown Average peak-to-trough decline	-33.43%	-24.85%	-8.58%
Ulcer Index Depth and duration of drawdowns from previous peaks	13.41%	7.35%	+6.06%

Volatility

NTRA vs. IBKR - Volatility Comparison

Natera, Inc. (NTRA) has a higher volatility of 14.27% compared to Interactive Brokers Group, Inc. (IBKR) at 11.31%. This indicates that NTRA's price experiences larger fluctuations and is considered to be riskier than IBKR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	NTRA	IBKR	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.27%	11.31%	+2.96%
Volatility (6M) Calculated over the trailing 6-month period	35.19%	27.82%	+7.37%
Volatility (1Y) Calculated over the trailing 1-year period	42.95%	37.67%	+5.28%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	57.04%	34.50%	+22.54%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	60.95%	33.37%	+27.58%

Dividends

NTRA vs. IBKR - Dividend Comparison

NTRA has not paid dividends to shareholders, while IBKR's dividend yield for the trailing twelve months is around 0.36%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IBKR Interactive Brokers Group, Inc.	0.36%	0.47%	0.48%	0.48%	0.55%	0.50%	0.66%	0.86%	0.73%	0.68%	1.10%	0.92%
NTRA Natera, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both NTRA and IBKR in my portfolio?

NTRA and IBKR have a correlation of 0.32, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, NTRA or IBKR?

NTRA has higher volatility (14.27%) compared to IBKR (11.31%). In terms of maximum drawdown, NTRA dropped -77.74% vs IBKR's -63.66%.

Which has better risk-adjusted returns?

IBKR currently has the higher Sharpe Ratio (2.08 vs 0.68), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.