KYMR vs. LENZ

Last updated Jun 3, 2026

KYMR (Kymera Therapeutics, Inc.) and LENZ (LENZ Therapeutics Inc) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, KYMR returned 38.13%/yr vs -10.35%/yr for LENZ. At a 0.33 correlation, their price movements are largely independent.

Performance

KYMR vs. LENZ - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Kymera Therapeutics, Inc. (KYMR) and LENZ Therapeutics Inc (LENZ). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, KYMR achieves a -8.38% return, which is significantly higher than LENZ's -55.44% return.

KYMR

• 1D: -9.15%
• 1M: -11.67%
• YTD: -8.38%
• 6M: 10.92%
• 1Y: 65.29%
• 3Y*: 38.13%
• 5Y*: 8.70%
• 10Y*: —

LENZ

• 1D: -4.17%
• 1M: -19.71%
• YTD: -55.44%
• 6M: -73.89%
• 1Y: -75.55%
• 3Y*: -10.35%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

KYMR vs. LENZ - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
KYMR Kymera Therapeutics, Inc.	-8.38%	93.41%	58.01%	2.00%	-60.69%	43.06%
LENZ LENZ Therapeutics Inc	-55.44%	-44.58%	230.71%	-21.08%	-73.29%	-32.81%

Correlation

The correlation between KYMR and LENZ is 0.25, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.25
Correlation (3Y) Calculated over the trailing 3-year period	0.33
Correlation (All Time) Calculated using the full available price history since Jun 28, 2021	0.33

Fundamentals

Market Cap KYMR : $6.95B LENZ : $223.54M
EPS KYMR : -$3.60 LENZ : -$3.66
PS Ratio KYMR : 121.09 LENZ : 10.11
PB Ratio KYMR : 4.52 LENZ : 0.91
Total Revenue (TTM) KYMR : $51.47M LENZ : $20.99M
Gross Profit (TTM) KYMR : $17.10M LENZ : $19.37M
EBITDA (TTM) KYMR : -$323.05M LENZ : -$116.01M

Return for Risk

KYMR vs. LENZ — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

KYMR

KYMR Risk / Return Rank: 81
KYMR Sharpe Ratio Rank: 73
KYMR Sortino Ratio Rank: 79
KYMR Omega Ratio Rank: 74
KYMR Calmar Ratio Rank: 91
KYMR Martin Ratio Rank: 89

LENZ

LENZ Risk / Return Rank: 6
LENZ Sharpe Ratio Rank: 6
LENZ Sortino Ratio Rank: 4
LENZ Omega Ratio Rank: 5
LENZ Calmar Ratio Rank: 7
LENZ Martin Ratio Rank: 7

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

KYMR vs. LENZ - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Kymera Therapeutics, Inc. (KYMR) and LENZ Therapeutics Inc (LENZ). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	KYMR	LENZ	Difference
Sharpe ratio Return per unit of total volatility	1.09	-0.93	+2.02
Sortino ratio Return per unit of downside risk	2.25	-1.64	+3.89
Omega ratio Gain probability vs. loss probability	1.26	0.79	+0.46
Calmar ratio Return relative to maximum drawdown	5.07	-0.87	+5.94
Martin ratio Return relative to average drawdown	11.90	-1.40	+13.30
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

KYMR vs. LENZ - Sharpe Ratio Comparison

The current KYMR Sharpe Ratio is 1.09, which is higher than the LENZ Sharpe Ratio of -0.93. The chart below compares the historical Sharpe Ratios of KYMR and LENZ, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	KYMR	LENZ	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.09	-0.93	+2.02
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.12	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.19	-0.46	+0.65

Drawdowns

KYMR vs. LENZ - Drawdown Comparison

The maximum KYMR drawdown since its inception was -87.51%, smaller than the maximum LENZ drawdown of -93.98%. Use the drawdown chart below to compare losses from any high point for KYMR and LENZ.

Drawdown Indicators

	KYMR	LENZ	Difference
Max Drawdown Largest peak-to-trough decline	-87.51%	-93.98%	+6.47%
Max Drawdown (1Y) Largest decline over 1 year	-27.74%	-86.44%	+58.70%
Max Drawdown (3Y) Largest decline over 3 years	-60.35%	-86.44%	+26.09%
Max Drawdown (5Y) Largest decline over 5 years	-83.54%	—	—
Current Drawdown Current decline from peak	-24.98%	-93.04%	+68.06%
Average Drawdown Average peak-to-trough decline	-49.50%	-78.61%	+29.11%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.81%	53.96%	-42.15%

Volatility

KYMR vs. LENZ - Volatility Comparison

The current volatility for Kymera Therapeutics, Inc. (KYMR) is 14.20%, while LENZ Therapeutics Inc (LENZ) has a volatility of 30.75%. This indicates that KYMR experiences smaller price fluctuations and is considered to be less risky than LENZ based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	KYMR	LENZ	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.20%	30.75%	-16.55%
Volatility (6M) Calculated over the trailing 6-month period	46.83%	62.95%	-16.12%
Volatility (1Y) Calculated over the trailing 1-year period	75.23%	81.32%	-6.09%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	73.15%	77.30%	-4.15%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	75.43%	77.30%	-1.87%

Dividends

KYMR vs. LENZ - Dividend Comparison

Neither KYMR nor LENZ has paid dividends to shareholders.

Position	TTM	2025	2024
KYMR Kymera Therapeutics, Inc.	0.00%	0.00%	0.00%
LENZ LENZ Therapeutics Inc	0.00%	0.00%	28.54%

Financials

Frequently Asked Questions

Can I hold both KYMR and LENZ in my portfolio?

KYMR and LENZ have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, KYMR or LENZ?

LENZ has higher volatility (30.75%) compared to KYMR (14.20%). In terms of maximum drawdown, KYMR dropped -87.51% vs LENZ's -93.98%.

Which has better risk-adjusted returns?

KYMR currently has the higher Sharpe Ratio (1.09 vs -0.93), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.