KYMR vs. ARVN

Last updated Jun 5, 2026

KYMR (Kymera Therapeutics, Inc.) and ARVN (Arvinas, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, KYMR returned 9.36%/yr vs -35.70%/yr for ARVN. At a 0.48 correlation, their price movements are largely independent.

Performance

KYMR vs. ARVN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Kymera Therapeutics, Inc. (KYMR) and Arvinas, Inc. (ARVN). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, KYMR achieves a -4.11% return, which is significantly higher than ARVN's -34.74% return.

KYMR

• 1D: 1.91%
• 1M: -9.79%
• YTD: -4.11%
• 6M: 12.65%
• 1Y: 68.57%
• 3Y*: 41.58%
• 5Y*: 9.36%
• 10Y*: —

ARVN

• 1D: 0.52%
• 1M: -27.05%
• YTD: -34.74%
• 6M: -38.33%
• 1Y: 11.37%
• 3Y*: -30.59%
• 5Y*: -35.70%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

KYMR vs. ARVN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
KYMR Kymera Therapeutics, Inc.	-4.11%	93.41%	58.01%	2.00%	-60.69%	2.40%	86.41%
ARVN Arvinas, Inc.	-34.74%	-38.13%	-53.43%	20.32%	-58.35%	-3.29%	234.37%

Correlation

The correlation between KYMR and ARVN is 0.40, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.40
Correlation (3Y) Calculated over the trailing 3-year period	0.46
Correlation (5Y) Calculated over the trailing 5-year period	0.51
Correlation (All Time) Calculated using the full available price history since Aug 24, 2020	0.48

The correlation between KYMR and ARVN shifts across timeframes, from 0.40 (1 year) to 0.51 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap KYMR : $7.28B ARVN : $495.36M
EPS KYMR : -$3.60 ARVN : -$3.22
PS Ratio KYMR : 126.73 ARVN : 5.95
PB Ratio KYMR : 4.73 ARVN : 1.28
Total Revenue (TTM) KYMR : $51.47M ARVN : $89.40M
Gross Profit (TTM) KYMR : $17.10M ARVN : $72.60M
EBITDA (TTM) KYMR : -$323.05M ARVN : -$233.90M

Return for Risk

KYMR vs. ARVN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

KYMR

KYMR Risk / Return Rank: 77
KYMR Sharpe Ratio Rank: 75
KYMR Sortino Ratio Rank: 80
KYMR Omega Ratio Rank: 75
KYMR Calmar Ratio Rank: 79
KYMR Martin Ratio Rank: 78

ARVN

ARVN Risk / Return Rank: 48
ARVN Sharpe Ratio Rank: 49
ARVN Sortino Ratio Rank: 47
ARVN Omega Ratio Rank: 46
ARVN Calmar Ratio Rank: 47
ARVN Martin Ratio Rank: 50

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

KYMR vs. ARVN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Kymera Therapeutics, Inc. (KYMR) and Arvinas, Inc. (ARVN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	KYMR	ARVN	Difference
Sharpe ratio: Return per unit of total volatility	1.15	0.20	+0.94
Sortino ratio: Return per unit of downside risk	2.32	0.69	+1.63
Omega ratio: Gain probability vs. loss probability	1.26	1.09	+0.18
Calmar ratio: Return relative to maximum drawdown	2.48	0.26	+2.23
Martin ratio: Return relative to average drawdown	5.75	0.77	+4.98
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

KYMR vs. ARVN - Sharpe Ratio Comparison

The current KYMR Sharpe Ratio is 1.15, which is higher than the ARVN Sharpe Ratio of 0.20. The chart below compares the historical Sharpe Ratios of KYMR and ARVN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	KYMR	ARVN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.15	0.20	+0.94
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.13	-0.52	+0.65
Sharpe Ratio (All Time) Calculated using the full available price history	0.20	-0.12	+0.32

Drawdowns

KYMR vs. ARVN - Drawdown Comparison

The maximum KYMR drawdown since its inception was -87.51%, smaller than the maximum ARVN drawdown of -94.37%. Use the drawdown chart below to compare losses from any high point for KYMR and ARVN.

Drawdown Indicators

	KYMR	ARVN	Difference
Max Drawdown Largest peak-to-trough decline	-87.51%	-94.37%	+6.86%
Max Drawdown (1Y) Largest decline over 1 year	-27.74%	-44.32%	+16.58%
Max Drawdown (3Y) Largest decline over 3 years	-60.35%	-88.40%	+28.05%
Max Drawdown (5Y) Largest decline over 5 years	-83.54%	-94.37%	+10.83%
Current Drawdown Current decline from peak	-21.49%	-92.82%	+71.33%
Average Drawdown Average peak-to-trough decline	-49.46%	-51.34%	+1.88%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.97%	14.82%	-2.85%

Volatility

KYMR vs. ARVN - Volatility Comparison

Kymera Therapeutics, Inc. (KYMR) and Arvinas, Inc. (ARVN) have volatilities of 14.18% and 13.74%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	KYMR	ARVN	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.18%	13.74%	+0.44%
Volatility (6M) Calculated over the trailing 6-month period	46.74%	37.14%	+9.60%
Volatility (1Y) Calculated over the trailing 1-year period	60.17%	56.16%	+4.01%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	73.16%	68.92%	+4.24%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	75.39%	77.75%	-2.36%

Dividends

KYMR vs. ARVN - Dividend Comparison

Neither KYMR nor ARVN has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both KYMR and ARVN in my portfolio?

KYMR and ARVN have a correlation of 0.40, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, KYMR or ARVN?

KYMR has higher volatility (14.18%) compared to ARVN (13.74%). In terms of maximum drawdown, KYMR dropped -87.51% vs ARVN's -94.37%.

Which has better risk-adjusted returns?

KYMR currently has the higher Sharpe Ratio (1.15 vs 0.20), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.