IPSC vs. IRWD

Last updated Apr 1, 2026

Compare and contrast key facts about Century Therapeutics, Inc. (IPSC) and Ironwood Pharmaceuticals, Inc. (IRWD).

Performance

IPSC vs. IRWD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Century Therapeutics, Inc. (IPSC) and Ironwood Pharmaceuticals, Inc. (IRWD). The values are adjusted to include any dividend payments, if applicable.

IPSC vs. IRWD - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
IPSC Century Therapeutics, Inc.	127.18%	-1.50%	-69.58%	-35.28%	-67.65%	-30.53%
IRWD Ironwood Pharmaceuticals, Inc.	4.15%	-23.93%	-61.28%	-7.67%	6.26%	-0.51%

Fundamentals

EPS IPSC : -$0.11 IRWD : $0.21
PS Ratio IPSC : 1.79 IRWD : 1.34
Total Revenue (TTM) IPSC : $109.16M IRWD : $296.15M
Gross Profit (TTM) IPSC : $102.83M IRWD : $221.01M
EBITDA (TTM) IPSC : -$3.89M IRWD : $121.85M

Returns By Period

In the year-to-date period, IPSC achieves a 127.18% return, which is significantly higher than IRWD's 4.15% return.

IPSC

• 1D: 11.33%
• 1M: -2.59%
• YTD: 127.18%
• 6M: 353.82%
• 1Y: 374.79%
• 3Y*: -13.32%
• 5Y*: —
• 10Y*: —

IRWD

• 1D: 8.67%
• 1M: 2.63%
• YTD: 4.15%
• 6M: 167.94%
• 1Y: 138.78%
• 3Y*: -30.64%
• 5Y*: -20.25%
• 10Y*: -10.96%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

IPSC vs. IRWD — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IPSC

IPSC Risk / Return Rank: 97
IPSC Sharpe Ratio Rank: 98
IPSC Sortino Ratio Rank: 97
IPSC Omega Ratio Rank: 95
IPSC Calmar Ratio Rank: 98
IPSC Martin Ratio Rank: 97

IRWD

IRWD Risk / Return Rank: 79
IRWD Sharpe Ratio Rank: 79
IRWD Sortino Ratio Rank: 83
IRWD Omega Ratio Rank: 77
IRWD Calmar Ratio Rank: 81
IRWD Martin Ratio Rank: 75

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IPSC vs. IRWD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Century Therapeutics, Inc. (IPSC) and Ironwood Pharmaceuticals, Inc. (IRWD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IPSC	IRWD	Difference
Sharpe ratio Return per unit of total volatility	3.79	1.19	+2.60
Sortino ratio Return per unit of downside risk	4.07	2.27	+1.80
Omega ratio Gain probability vs. loss probability	1.49	1.27	+0.23
Calmar ratio Return relative to maximum drawdown	9.21	2.42	+6.79
Martin ratio Return relative to average drawdown	20.71	4.56	+16.15
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IPSC vs. IRWD - Sharpe Ratio Comparison

The current IPSC Sharpe Ratio is 3.79, which is higher than the IRWD Sharpe Ratio of 1.19. The chart below compares the historical Sharpe Ratios of IPSC and IRWD, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	IPSC	IRWD	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	3.79	1.19	+2.60
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.28	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.18	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.45	-0.13	-0.33

Correlation

The correlation between IPSC and IRWD is 0.23, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

IPSC vs. IRWD - Dividend Comparison

Neither IPSC nor IRWD has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

IPSC vs. IRWD - Drawdown Comparison

The maximum IPSC drawdown since its inception was -98.78%, roughly equal to the maximum IRWD drawdown of -97.31%. Use the drawdown chart below to compare losses from any high point for IPSC and IRWD.

Drawdown Indicators

	IPSC	IRWD	Difference
Max Drawdown Largest peak-to-trough decline	-98.78%	-97.31%	-1.47%
Max Drawdown (1Y) Largest decline over 1 year	-36.98%	-60.67%	+23.69%
Max Drawdown (5Y) Largest decline over 5 years	—	-96.33%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-97.31%	—
Current Drawdown Current decline from peak	-92.92%	-83.34%	-9.58%
Average Drawdown Average peak-to-trough decline	-80.03%	-38.79%	-41.24%
Ulcer Index Depth and duration of drawdowns from previous peaks	16.45%	32.67%	-16.22%

Volatility

IPSC vs. IRWD - Volatility Comparison

Century Therapeutics, Inc. (IPSC) has a higher volatility of 28.21% compared to Ironwood Pharmaceuticals, Inc. (IRWD) at 21.52%. This indicates that IPSC's price experiences larger fluctuations and is considered to be riskier than IRWD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IPSC	IRWD	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.21%	21.52%	+6.69%
Volatility (6M) Calculated over the trailing 6-month period	81.70%	76.33%	+5.37%
Volatility (1Y) Calculated over the trailing 1-year period	99.88%	117.03%	-17.15%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	84.63%	71.72%	+12.91%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	84.63%	60.32%	+24.31%

Financials