INCY vs. TWLO
INCY (Incyte Corporation) and TWLO (Twilio Inc.) are both stocks. INCY operates in Biotechnology (Healthcare), while TWLO operates in Internet Content & Information (Communication Services). Over the past 5 years, INCY returned 5.62%/yr vs -9.31%/yr for TWLO. At a 0.24 correlation, their price movements are largely independent.
Performance
INCY vs. TWLO - Performance Comparison
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Returns By Period
In the year-to-date period, INCY achieves a 9.88% return, which is significantly lower than TWLO's 43.48% return.
INCY
- 1D
- 0.65%
- 1M
- 13.87%
- YTD
- 9.88%
- 6M
- 13.75%
- 1Y
- 60.19%
- 3Y*
- 20.55%
- 5Y*
- 5.62%
- 10Y*
- 3.13%
TWLO
- 1D
- -1.23%
- 1M
- 2.92%
- YTD
- 43.48%
- 6M
- 53.54%
- 1Y
- 79.98%
- 3Y*
- 45.13%
- 5Y*
- -9.31%
- 10Y*
- —
INCY vs. TWLO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
INCY Incyte Corporation | 9.88% | 43.00% | 10.00% | -21.83% | 9.43% | -15.61% | -0.39% | 37.32% | -32.86% | -5.55% |
TWLO Twilio Inc. | 43.48% | 31.61% | 42.45% | 54.96% | -81.41% | -22.20% | 244.42% | 10.06% | 278.39% | -18.20% |
Correlation
The correlation between INCY and TWLO is 0.08, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.08 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.17 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.22 |
Correlation (All Time) Calculated using the full available price history since Jun 23, 2016 | 0.24 |
The correlation between INCY and TWLO shifts across timeframes, from 0.08 (1 year) to 0.24 (all time), reflecting how their relationship changes across market environments.
Fundamentals
INCY:
$22.45B
TWLO:
$32.20B
INCY:
$7.06
TWLO:
$0.66
INCY:
15.38
TWLO:
308.70
INCY:
4.11
TWLO:
6.05
INCY:
3.99
TWLO:
4.14
INCY:
$5.36B
TWLO:
$5.30B
INCY:
$3.76B
TWLO:
$2.59B
INCY:
$1.80B
TWLO:
$304.06M
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Return for Risk
INCY vs. TWLO — Risk / Return Rank
INCY
TWLO
INCY vs. TWLO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Incyte Corporation (INCY) and Twilio Inc. (TWLO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| INCY | TWLO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.46 | ||
| Sortino ratioReturn per unit of downside risk | +0.47 | ||
| Omega ratioGain probability vs. loss probability | 1.31 | 1.27 | +0.04 |
| Calmar ratioReturn relative to maximum drawdown | 3.11 | 2.53 | +0.59 |
| Martin ratioReturn relative to average drawdown | 6.94 | 5.73 | +1.21 |
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Drawdowns
INCY vs. TWLO - Drawdown Comparison
The maximum INCY drawdown since its inception was -98.54%, which is greater than TWLO's maximum drawdown of -90.36%. Use the drawdown chart below to compare losses from any high point for INCY and TWLO.
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Drawdown Indicators
| INCY | TWLO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.54% | -90.36% | -8.18% |
Max Drawdown (1Y)Largest decline over 1 year | -18.33% | -30.34% | +12.01% |
Max Drawdown (3Y)Largest decline over 3 years | -33.83% | -45.17% | +11.34% |
Max Drawdown (5Y)Largest decline over 5 years | -41.06% | -89.57% | +48.51% |
Max Drawdown (10Y)Largest decline over 10 years | -66.47% | — | — |
Current DrawdownCurrent decline from peak | -28.91% | -53.98% | +25.07% |
Average DrawdownAverage peak-to-trough decline | -59.88% | -49.51% | -10.37% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 8.21% | 13.35% | -5.14% |
Volatility
INCY vs. TWLO - Volatility Comparison
The current volatility for Incyte Corporation (INCY) is 9.64%, while Twilio Inc. (TWLO) has a volatility of 22.34%. This indicates that INCY experiences smaller price fluctuations and is considered to be less risky than TWLO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| INCY | TWLO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 9.64% | 22.34% | -12.70% |
Volatility (6M)Calculated over the trailing 6-month period | 22.73% | 43.22% | -20.49% |
Volatility (1Y)Calculated over the trailing 1-year period | 33.10% | 60.54% | -27.44% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 29.32% | 59.33% | -30.01% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 34.29% | 61.05% | -26.76% |
Dividends
INCY vs. TWLO - Dividend Comparison
Neither INCY nor TWLO has paid dividends to shareholders.
Financials
INCY vs. TWLO - Financials Comparison
This section allows you to compare key financial metrics between Incyte Corporation and Twilio Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
INCY vs. TWLO - Profitability Comparison
INCY - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported a gross profit of 0.00 and revenue of 1.27B. Therefore, the gross margin over that period was 0.0%.
TWLO - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Twilio Inc. reported a gross profit of 684.24M and revenue of 1.41B. Therefore, the gross margin over that period was 48.6%.
INCY - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported an operating income of 301.12M and revenue of 1.27B, resulting in an operating margin of 23.7%.
TWLO - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Twilio Inc. reported an operating income of 107.67M and revenue of 1.41B, resulting in an operating margin of 7.7%.
INCY - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported a net income of 303.33M and revenue of 1.27B, resulting in a net margin of 23.8%.
TWLO - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Twilio Inc. reported a net income of 90.14M and revenue of 1.41B, resulting in a net margin of 6.4%.
Frequently Asked Questions
INCY and TWLO have a correlation of 0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TWLO has higher volatility (22.34%) compared to INCY (9.64%). In terms of maximum drawdown, INCY dropped -98.54% vs TWLO's -90.36%.
INCY currently has the higher Sharpe Ratio (1.72 vs 1.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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