IMRX vs. MPWR

Last updated Jun 13, 2026

IMRX (Immuneering Corporation) and MPWR (Monolithic Power Systems, Inc.) are both stocks. IMRX operates in Biotechnology (Healthcare), while MPWR operates in Semiconductors (Technology). Over the past 3 years, IMRX returned -24.01%/yr vs 44.43%/yr for MPWR. At a 0.19 correlation, their price movements are largely independent.

Performance

IMRX vs. MPWR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Immuneering Corporation (IMRX) and Monolithic Power Systems, Inc. (MPWR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IMRX achieves a -36.32% return, which is significantly lower than MPWR's 74.38% return.

IMRX

• 1D: 1.70%
• 1M: -22.12%
• YTD: -36.32%
• 6M: -31.09%
• 1Y: 113.78%
• 3Y*: -24.01%
• 5Y*: —
• 10Y*: —

MPWR

• 1D: -0.77%
• 1M: -4.43%
• YTD: 74.38%
• 6M: 67.26%
• 1Y: 121.18%
• 3Y*: 44.43%
• 5Y*: 36.35%
• 10Y*: 37.94%

*Multi-year figures are annualized to reflect compound growth (CAGR)

IMRX vs. MPWR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
IMRX Immuneering Corporation	-36.32%	199.09%	-70.07%	51.55%	-70.01%	-17.08%
MPWR Monolithic Power Systems, Inc.	74.38%	54.45%	-5.55%	79.78%	-27.78%	12.38%

Correlation

The correlation between IMRX and MPWR is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.16
Correlation (3Y) Calculated over the trailing 3-year period	0.16
Correlation (All Time) Calculated using the full available price history since Jul 30, 2021	0.19

Fundamentals

Market Cap IMRX : $270.92M MPWR : $77.67B
EPS IMRX : -$293.00 MPWR : $13.89
PB Ratio IMRX : 0.00 MPWR : 21.12
Total Revenue (TTM) IMRX : $0.00 MPWR : $2.96B
Gross Profit (TTM) IMRX : -$698.89K MPWR : $1.63B
EBITDA (TTM) IMRX : -$15.38B MPWR : $861.78M

Return for Risk

IMRX vs. MPWR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IMRX

IMRX Risk / Return Rank: 75
IMRX Sharpe Ratio Rank: 72
IMRX Sortino Ratio Rank: 78
IMRX Omega Ratio Rank: 81
IMRX Calmar Ratio Rank: 76
IMRX Martin Ratio Rank: 70

MPWR

MPWR Risk / Return Rank: 91
MPWR Sharpe Ratio Rank: 93
MPWR Sortino Ratio Rank: 90
MPWR Omega Ratio Rank: 88
MPWR Calmar Ratio Rank: 93
MPWR Martin Ratio Rank: 93

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IMRX vs. MPWR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Immuneering Corporation (IMRX) and Monolithic Power Systems, Inc. (MPWR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	IMRX	MPWR	Difference
Sharpe ratio: Return per unit of total volatility	0.92	2.51	-1.59
Sortino ratio: Return per unit of downside risk	2.05	3.00	-0.95
Omega ratio: Gain probability vs. loss probability	1.29	1.37	-0.08
Calmar ratio: Return relative to maximum drawdown	1.98	5.43	-3.44
Martin ratio: Return relative to average drawdown	3.30	14.45	-11.15

IMRX vs. MPWR - Sharpe Ratio Comparison

The current IMRX Sharpe Ratio is 0.92, which is lower than the MPWR Sharpe Ratio of 2.51. The chart below compares the historical Sharpe Ratios of IMRX and MPWR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

IMRX vs. MPWR - Drawdown Comparison

The maximum IMRX drawdown since its inception was -96.86%, which is greater than MPWR's maximum drawdown of -72.27%. Use the drawdown chart below to compare losses from any high point for IMRX and MPWR.

Drawdown Indicators

	IMRX	MPWR	Difference
Max Drawdown Largest peak-to-trough decline	-96.86%	-72.27%	-24.59%
Max Drawdown (1Y) Largest decline over 1 year	-57.67%	-22.45%	-35.22%
Max Drawdown (3Y) Largest decline over 3 years	-90.98%	-51.65%	-39.33%
Max Drawdown (5Y) Largest decline over 5 years	—	-51.65%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-51.65%	—
Current Drawdown Current decline from peak	-87.24%	-6.66%	-80.58%
Average Drawdown Average peak-to-trough decline	-77.61%	-17.71%	-59.90%
Ulcer Index Depth and duration of drawdowns from previous peaks	34.56%	8.44%	+26.12%

Volatility

IMRX vs. MPWR - Volatility Comparison

Immuneering Corporation (IMRX) has a higher volatility of 33.75% compared to Monolithic Power Systems, Inc. (MPWR) at 20.33%. This indicates that IMRX's price experiences larger fluctuations and is considered to be riskier than MPWR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IMRX	MPWR	Difference
Volatility (1M) Calculated over the trailing 1-month period	33.75%	20.33%	+13.42%
Volatility (6M) Calculated over the trailing 6-month period	79.00%	37.42%	+41.58%
Volatility (1Y) Calculated over the trailing 1-year period	124.22%	48.53%	+75.69%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	114.45%	53.53%	+60.92%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	114.45%	47.23%	+67.22%

Dividends

IMRX vs. MPWR - Dividend Comparison

IMRX has not paid dividends to shareholders, while MPWR's dividend yield for the trailing twelve months is around 0.42%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IMRX Immuneering Corporation	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
MPWR Monolithic Power Systems, Inc.	0.42%	0.69%	0.85%	0.63%	0.85%	0.49%	0.55%	0.90%	1.03%	0.71%	0.98%	1.26%

Financials

Frequently Asked Questions

Can I hold both IMRX and MPWR in my portfolio?

IMRX and MPWR have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IMRX or MPWR?

IMRX has higher volatility (33.75%) compared to MPWR (20.33%). In terms of maximum drawdown, IMRX dropped -96.86% vs MPWR's -72.27%.

Which has better risk-adjusted returns?

MPWR currently has the higher Sharpe Ratio (2.51 vs 0.92), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.