IHI vs. GNOM

Last updated Jun 6, 2026

IHI (iShares U.S. Medical Devices ETF) and GNOM (Global X Genomics & Biotechnology ETF) are both Health & Biotech Equities funds - IHI tracks the Dow Jones U.S. Select Medical Equipment Index while GNOM tracks the Solactive Genomics Index. Both are passively managed. Over the past 5 years, IHI returned -1.87%/yr vs -10.36%/yr for GNOM. A 0.58 correlation means they provide meaningful diversification when combined. IHI charges 0.43%/yr vs 0.50%/yr for GNOM.

Performance

IHI vs. GNOM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares U.S. Medical Devices ETF (IHI) and Global X Genomics & Biotechnology ETF (GNOM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IHI achieves a -19.36% return, which is significantly lower than GNOM's 6.84% return.

IHI

• 1D: 0.42%
• 1M: 0.74%
• YTD: -19.36%
• 6M: -20.97%
• 1Y: -18.97%
• 3Y*: -1.89%
• 5Y*: -1.87%
• 10Y*: 8.90%

GNOM

• 1D: -4.23%
• 1M: 3.36%
• YTD: 6.84%
• 6M: 4.93%
• 1Y: 51.76%
• 3Y*: -1.47%
• 5Y*: -10.36%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

IHI vs. GNOM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
IHI iShares U.S. Medical Devices ETF	-19.36%	6.88%	8.62%	3.24%	-19.80%	21.03%	24.17%	15.23%
GNOM Global X Genomics & Biotechnology ETF	6.84%	18.65%	-15.99%	-8.63%	-36.27%	-15.93%	51.52%	1.56%

Correlation

The correlation between IHI and GNOM is 0.45, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.45
Correlation (3Y) Calculated over the trailing 3-year period	0.48
Correlation (5Y) Calculated over the trailing 5-year period	0.57
Correlation (All Time) Calculated using the full available price history since Apr 11, 2019	0.58

The correlation between IHI and GNOM shifts across timeframes, from 0.45 (1 year) to 0.58 (all time), reflecting how their relationship changes across market environments.

IHI vs. GNOM - Sectors Allocation Comparison

Sectors	IHI	GNOM
Healthcare	100.0%	99.6%
Industrials	0.2%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-
Real Estate	-	-
Technology	-	0.4%
Utilities	-	-

Return for Risk

IHI vs. GNOM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IHI

IHI Risk / Return Rank: 1
IHI Sharpe Ratio Rank: 1
IHI Sortino Ratio Rank: 1
IHI Omega Ratio Rank: 2
IHI Calmar Ratio Rank: 3
IHI Martin Ratio Rank: 0

GNOM

GNOM Risk / Return Rank: 57
GNOM Sharpe Ratio Rank: 59
GNOM Sortino Ratio Rank: 61
GNOM Omega Ratio Rank: 53
GNOM Calmar Ratio Rank: 60
GNOM Martin Ratio Rank: 51

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IHI vs. GNOM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares U.S. Medical Devices ETF (IHI) and Global X Genomics & Biotechnology ETF (GNOM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IHI	GNOM	Difference
Sharpe ratio: Return per unit of total volatility	-1.12	1.93	-3.05
Sortino ratio: Return per unit of downside risk	-1.56	2.73	-4.29
Omega ratio: Gain probability vs. loss probability	0.83	1.31	-0.48
Calmar ratio: Return relative to maximum drawdown	-0.73	2.86	-3.59
Martin ratio: Return relative to average drawdown	-1.83	8.23	-10.06
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IHI vs. GNOM - Sharpe Ratio Comparison

The current IHI Sharpe Ratio is -1.12, which is lower than the GNOM Sharpe Ratio of 1.93. The chart below compares the historical Sharpe Ratios of IHI and GNOM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	IHI	GNOM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-1.12	1.93	-3.05
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.10	-0.31	+0.21
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.45	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.47	-0.09	+0.56

Drawdowns

IHI vs. GNOM - Drawdown Comparison

The maximum IHI drawdown since its inception was -49.65%, smaller than the maximum GNOM drawdown of -75.00%. Use the drawdown chart below to compare losses from any high point for IHI and GNOM.

Drawdown Indicators

	IHI	GNOM	Difference
Max Drawdown Largest peak-to-trough decline	-49.65%	-75.00%	+25.35%
Max Drawdown (1Y) Largest decline over 1 year	-26.11%	-18.17%	-7.94%
Max Drawdown (3Y) Largest decline over 3 years	-26.64%	-46.47%	+19.83%
Max Drawdown (5Y) Largest decline over 5 years	-33.12%	-72.29%	+39.17%
Max Drawdown (10Y) Largest decline over 10 years	-33.25%	—	—
Current Drawdown Current decline from peak	-23.85%	-55.85%	+32.00%
Average Drawdown Average peak-to-trough decline	-8.32%	-40.57%	+32.25%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.38%	6.31%	+4.07%

Volatility

IHI vs. GNOM - Volatility Comparison

The current volatility for iShares U.S. Medical Devices ETF (IHI) is 7.02%, while Global X Genomics & Biotechnology ETF (GNOM) has a volatility of 9.57%. This indicates that IHI experiences smaller price fluctuations and is considered to be less risky than GNOM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IHI	GNOM	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.02%	9.57%	-2.55%
Volatility (6M) Calculated over the trailing 6-month period	13.06%	19.99%	-6.93%
Volatility (1Y) Calculated over the trailing 1-year period	16.97%	27.01%	-10.04%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	18.99%	33.65%	-14.66%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	19.80%	34.21%	-14.41%

IHI vs. GNOM - Expense Ratio Comparison

IHI has a 0.43% expense ratio, which is lower than GNOM's 0.50% expense ratio.

Dividends

IHI vs. GNOM - Dividend Comparison

IHI's dividend yield for the trailing twelve months is around 0.44%, less than GNOM's 1.29% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
GNOM Global X Genomics & Biotechnology ETF	1.29%	1.37%	0.00%	0.00%	0.00%	0.03%	0.14%	0.00%	0.00%	0.00%	0.00%	0.00%
IHI iShares U.S. Medical Devices ETF	0.44%	0.34%	0.46%	0.53%	0.45%	0.25%	0.25%	0.33%	0.26%	0.37%	0.55%	1.28%

Frequently Asked Questions

Can I hold both IHI and GNOM in my portfolio?

IHI and GNOM have a correlation of 0.45, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IHI or GNOM?

GNOM has higher volatility (9.57%) compared to IHI (7.02%). In terms of maximum drawdown, IHI dropped -49.65% vs GNOM's -75.00%.

Which ETF is better, IHI or GNOM?

On 5-year performance, IHI leads with -1.87% vs -10.36% for GNOM. On fees, IHI is cheaper at 0.43% per year. On volatility, IHI has been the lower-risk option at 7.02%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IHI or GNOM?

Over the 5-year period, IHI has performed better with a -1.87% return vs -10.36%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IHI or GNOM?

IHI is cheaper with a 0.43% expense ratio, compared with 0.50% for GNOM.

Which ETF pays a higher dividend yield, IHI or GNOM?

GNOM has the higher dividend yield at 1.29%, compared with 0.44% for IHI.

What is the main difference between IHI and GNOM?

IHI tracks Dow Jones U.S. Select Medical Equipment Index, while GNOM tracks Solactive Genomics Index. They also come from different issuers: iShares and Global X. Their fees differ too: 0.43% for IHI and 0.50% for GNOM.

Which has better risk-adjusted returns?

GNOM currently has the higher Sharpe Ratio (1.93 vs -1.12), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.