IHE vs. ACWI

Last updated Jun 4, 2026

IHE (iShares U.S. Pharmaceuticals ETF) and ACWI (iShares MSCI ACWI ETF) are both exchange-traded funds - IHE is a Health & Biotech Equities fund tracking the Dow Jones U.S. Select Pharmaceuticals Index, while ACWI is a Global Equities fund tracking the MSCI All Country World Index. Both are passively managed. Over the past 10 years, IHE returned 7.81%/yr vs 12.85%/yr for ACWI. A 0.64 correlation means they provide meaningful diversification when combined. IHE charges 0.42%/yr vs 0.32%/yr for ACWI.

Performance

IHE vs. ACWI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares U.S. Pharmaceuticals ETF (IHE) and iShares MSCI ACWI ETF (ACWI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IHE achieves a 6.47% return, which is significantly lower than ACWI's 12.13% return. Over the past 10 years, IHE has underperformed ACWI with an annualized return of 7.81%, while ACWI has yielded a comparatively higher 12.85% annualized return.

IHE

• 1D: 1.16%
• 1M: 1.80%
• YTD: 6.47%
• 6M: 8.51%
• 1Y: 40.15%
• 3Y*: 17.47%
• 5Y*: 9.98%
• 10Y*: 7.81%

ACWI

• 1D: -0.83%
• 1M: 5.28%
• YTD: 12.13%
• 6M: 12.96%
• 1Y: 29.18%
• 3Y*: 21.15%
• 5Y*: 11.28%
• 10Y*: 12.85%

*Multi-year figures are annualized to reflect compound growth (CAGR)

IHE vs. ACWI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
IHE iShares U.S. Pharmaceuticals ETF	6.47%	31.69%	8.13%	1.06%	-4.87%	13.07%	13.66%	15.47%	-7.76%	10.64%
ACWI iShares MSCI ACWI ETF	12.13%	22.41%	17.45%	22.27%	-18.39%	18.66%	16.34%	26.59%	-9.19%	24.33%

Correlation

The correlation between IHE and ACWI is 0.37, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.37
Correlation (3Y) Calculated over the trailing 3-year period	0.45
Correlation (5Y) Calculated over the trailing 5-year period	0.53
Correlation (10Y) Calculated over the trailing 10-year period	0.58
Correlation (All Time) Calculated using the full available price history since Mar 31, 2008	0.64

Over the past year, the correlation between IHE and ACWI has dropped to 0.37 - well below their long-term average of 0.64, suggesting their price drivers have been diverging.

IHE vs. ACWI - Sectors Allocation Comparison

Sectors	IHE	ACWI
Healthcare	100.0%	8.1%
Basic Materials	-	3.7%
Communication Services	-	9.0%
Consumer Cyclical	-	9.3%
Consumer Defensive	-	5.0%
Energy	-	4.2%
Financial Services	-	16.1%
Industrials	-	10.9%
Real Estate	-	1.8%
Technology	-	29.4%
Utilities	-	2.6%

Return for Risk

IHE vs. ACWI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IHE

IHE Risk / Return Rank: 74
IHE Sharpe Ratio Rank: 71
IHE Sortino Ratio Rank: 75
IHE Omega Ratio Rank: 65
IHE Calmar Ratio Rank: 85
IHE Martin Ratio Rank: 75

ACWI

ACWI Risk / Return Rank: 66
ACWI Sharpe Ratio Rank: 68
ACWI Sortino Ratio Rank: 67
ACWI Omega Ratio Rank: 67
ACWI Calmar Ratio Rank: 59
ACWI Martin Ratio Rank: 71

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IHE vs. ACWI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares U.S. Pharmaceuticals ETF (IHE) and iShares MSCI ACWI ETF (ACWI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IHE	ACWI	Difference
Sharpe ratio: Return per unit of total volatility	2.36	2.29	+0.07
Sortino ratio: Return per unit of downside risk	3.43	3.17	+0.26
Omega ratio: Gain probability vs. loss probability	1.40	1.41	-0.01
Calmar ratio: Return relative to maximum drawdown	4.76	3.01	+1.75
Martin ratio: Return relative to average drawdown	14.35	13.53	+0.82
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IHE vs. ACWI - Sharpe Ratio Comparison

The current IHE Sharpe Ratio is 2.36, which is comparable to the ACWI Sharpe Ratio of 2.29. The chart below compares the historical Sharpe Ratios of IHE and ACWI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	IHE	ACWI	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.36	2.29	+0.07
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.62	0.71	-0.09
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.43	0.75	-0.32
Sharpe Ratio (All Time) Calculated using the full available price history	0.51	0.43	+0.08

Drawdowns

IHE vs. ACWI - Drawdown Comparison

The maximum IHE drawdown since its inception was -38.20%, smaller than the maximum ACWI drawdown of -56.00%. Use the drawdown chart below to compare losses from any high point for IHE and ACWI.

Drawdown Indicators

	IHE	ACWI	Difference
Max Drawdown Largest peak-to-trough decline	-38.20%	-56.00%	+17.80%
Max Drawdown (1Y) Largest decline over 1 year	-8.47%	-9.73%	+1.26%
Max Drawdown (3Y) Largest decline over 3 years	-15.92%	-16.55%	+0.63%
Max Drawdown (5Y) Largest decline over 5 years	-16.03%	-26.42%	+10.39%
Max Drawdown (10Y) Largest decline over 10 years	-29.59%	-33.53%	+3.94%
Current Drawdown Current decline from peak	-2.80%	-0.83%	-1.97%
Average Drawdown Average peak-to-trough decline	-7.92%	-8.61%	+0.69%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.81%	2.16%	+0.65%

Volatility

IHE vs. ACWI - Volatility Comparison

iShares U.S. Pharmaceuticals ETF (IHE) has a higher volatility of 5.53% compared to iShares MSCI ACWI ETF (ACWI) at 3.93%. This indicates that IHE's price experiences larger fluctuations and is considered to be riskier than ACWI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IHE	ACWI	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.53%	3.93%	+1.60%
Volatility (6M) Calculated over the trailing 6-month period	12.48%	10.29%	+2.19%
Volatility (1Y) Calculated over the trailing 1-year period	17.07%	12.78%	+4.29%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	16.24%	16.05%	+0.19%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.05%	17.11%	+0.94%

IHE vs. ACWI - Expense Ratio Comparison

IHE has a 0.42% expense ratio, which is higher than ACWI's 0.32% expense ratio.

Dividends

IHE vs. ACWI - Dividend Comparison

IHE's dividend yield for the trailing twelve months is around 1.65%, more than ACWI's 1.38% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ACWI iShares MSCI ACWI ETF	1.38%	1.55%	1.70%	1.88%	1.79%	1.71%	1.43%	2.33%	2.18%	1.94%	2.19%	2.56%
IHE iShares U.S. Pharmaceuticals ETF	1.65%	1.76%	1.73%	1.39%	2.01%	1.49%	1.19%	1.40%	1.25%	1.36%	0.92%	1.93%

Frequently Asked Questions

Can I hold both IHE and ACWI in my portfolio?

IHE and ACWI have a correlation of 0.37, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IHE or ACWI?

IHE has higher volatility (5.53%) compared to ACWI (3.93%). In terms of maximum drawdown, IHE dropped -38.20% vs ACWI's -56.00%.

Which ETF is better, IHE or ACWI?

On 10-year performance, ACWI leads with 12.85% vs 7.81% for IHE. On fees, ACWI is cheaper at 0.32% per year. On volatility, ACWI has been the lower-risk option at 3.93%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IHE or ACWI?

Over the 10-year period, ACWI has performed better with a 12.85% return vs 7.81%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IHE or ACWI?

ACWI is cheaper with a 0.32% expense ratio, compared with 0.42% for IHE.

Which ETF pays a higher dividend yield, IHE or ACWI?

IHE has the higher dividend yield at 1.65%, compared with 1.38% for ACWI.

What is the main difference between IHE and ACWI?

IHE is categorized as Health & Biotech Equities, while ACWI is Global Equities. IHE tracks Dow Jones U.S. Select Pharmaceuticals Index, while ACWI tracks MSCI All Country World Index. Their fees differ too: 0.42% for IHE and 0.32% for ACWI.

Which has better risk-adjusted returns?

IHE currently has the higher Sharpe Ratio (2.36 vs 2.29), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.