HEAE.L vs. CNDX.L

Last updated Jun 5, 2026

HEAE.L (SPDR MSCI Europe Health Care UCITS ETF) and CNDX.L (iShares NASDAQ 100 UCITS ETF) are both exchange-traded funds - HEAE.L is a Health & Biotech Equities fund tracking the MSCI World/Health Care NR USD, while CNDX.L is a Nasdaq-100 fund tracking the NASDAQ-100 Index. Both are passively managed. Over the past 3 years, HEAE.L returned 2.88%/yr vs 24.77%/yr for CNDX.L. At a 0.16 correlation, their price movements are largely independent. HEAE.L charges 0.18%/yr vs 0.33%/yr for CNDX.L.

Performance

HEAE.L vs. CNDX.L - Performance Comparison

The chart below illustrates the hypothetical performance of a £10,000 investment in SPDR MSCI Europe Health Care UCITS ETF (HEAE.L) and iShares NASDAQ 100 UCITS ETF (CNDX.L). The values are adjusted to include any dividend payments, if applicable.

Different Trading Currencies

HEAE.L is traded in GBP, while CNDX.L is traded in USD. To make them comparable, the CNDX.L values have been converted to GBP using the latest available exchange rates.

Returns By Period

In the year-to-date period, HEAE.L achieves a -2.42% return, which is significantly lower than CNDX.L's 20.14% return.

HEAE.L

• 1D: 3.29%
• 1M: 1.82%
• YTD: -2.42%
• 6M: -1.32%
• 1Y: 9.06%
• 3Y*: 2.88%
• 5Y*: —
• 10Y*: —

CNDX.L

• 1D: -0.66%
• 1M: 9.52%
• YTD: 20.14%
• 6M: 18.27%
• 1Y: 41.64%
• 3Y*: 24.77%
• 5Y*: 18.88%
• 10Y*: 22.53%

*Multi-year figures are annualized to reflect compound growth (CAGR)

HEAE.L vs. CNDX.L - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
HEAE.L SPDR MSCI Europe Health Care UCITS ETF	-2.42%	13.38%	-1.21%	5.53%	-5.60%
CNDX.L iShares NASDAQ 100 UCITS ETF	20.14%	11.22%	28.66%	48.50%	-18.49%

Correlation

The correlation between HEAE.L and CNDX.L is 0.09, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.09
Correlation (3Y) Calculated over the trailing 3-year period	0.17
Correlation (All Time) Calculated using the full available price history since Apr 11, 2022	0.16

Return for Risk

HEAE.L vs. CNDX.L — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

HEAE.L

HEAE.L Risk / Return Rank: 18
HEAE.L Sharpe Ratio Rank: 18
HEAE.L Sortino Ratio Rank: 18
HEAE.L Omega Ratio Rank: 18
HEAE.L Calmar Ratio Rank: 17
HEAE.L Martin Ratio Rank: 17

CNDX.L

CNDX.L Risk / Return Rank: 75
CNDX.L Sharpe Ratio Rank: 79
CNDX.L Sortino Ratio Rank: 79
CNDX.L Omega Ratio Rank: 74
CNDX.L Calmar Ratio Rank: 73
CNDX.L Martin Ratio Rank: 71

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

HEAE.L vs. CNDX.L - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for SPDR MSCI Europe Health Care UCITS ETF (HEAE.L) and iShares NASDAQ 100 UCITS ETF (CNDX.L). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	HEAE.L	CNDX.L	Difference
Sharpe ratio: Return per unit of total volatility	0.54	2.61	-2.07
Sortino ratio: Return per unit of downside risk	0.90	3.49	-2.59
Omega ratio: Gain probability vs. loss probability	1.11	1.46	-0.36
Calmar ratio: Return relative to maximum drawdown	0.66	3.70	-3.04
Martin ratio: Return relative to average drawdown	1.57	10.51	-8.95
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

HEAE.L vs. CNDX.L - Sharpe Ratio Comparison

The current HEAE.L Sharpe Ratio is 0.54, which is lower than the CNDX.L Sharpe Ratio of 2.61. The chart below compares the historical Sharpe Ratios of HEAE.L and CNDX.L, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	HEAE.L	CNDX.L	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.54	2.61	-2.07
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.94	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	1.11	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.14	1.17	-1.03

Drawdowns

HEAE.L vs. CNDX.L - Drawdown Comparison

The maximum HEAE.L drawdown since its inception was -24.51%, smaller than the maximum CNDX.L drawdown of -27.74%. Use the drawdown chart below to compare losses from any high point for HEAE.L and CNDX.L.

Drawdown Indicators

	HEAE.L	CNDX.L	Difference
Max Drawdown Largest peak-to-trough decline	-24.51%	-27.74%	+3.23%
Max Drawdown (1Y) Largest decline over 1 year	-13.73%	-11.11%	-2.62%
Max Drawdown (3Y) Largest decline over 3 years	-24.51%	-24.37%	-0.14%
Max Drawdown (5Y) Largest decline over 5 years	—	-27.74%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-27.74%	—
Current Drawdown Current decline from peak	-10.88%	-0.66%	-10.22%
Average Drawdown Average peak-to-trough decline	-7.69%	-4.72%	-2.97%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.78%	3.93%	+1.85%

Volatility

HEAE.L vs. CNDX.L - Volatility Comparison

SPDR MSCI Europe Health Care UCITS ETF (HEAE.L) has a higher volatility of 5.60% compared to iShares NASDAQ 100 UCITS ETF (CNDX.L) at 4.89%. This indicates that HEAE.L's price experiences larger fluctuations and is considered to be riskier than CNDX.L based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	HEAE.L	CNDX.L	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.60%	4.89%	+0.71%
Volatility (6M) Calculated over the trailing 6-month period	12.12%	11.60%	+0.52%
Volatility (1Y) Calculated over the trailing 1-year period	16.79%	15.74%	+1.05%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	16.28%	20.08%	-3.80%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	16.28%	20.20%	-3.92%

HEAE.L vs. CNDX.L - Expense Ratio Comparison

HEAE.L has a 0.18% expense ratio, which is lower than CNDX.L's 0.33% expense ratio.

Dividends

HEAE.L vs. CNDX.L - Dividend Comparison

Neither HEAE.L nor CNDX.L has paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CNDX.L iShares NASDAQ 100 UCITS ETF	0.00%	0.00%	0.02%	0.05%	0.06%	0.03%	0.04%	0.07%	0.06%	0.30%	0.16%	0.16%
HEAE.L SPDR MSCI Europe Health Care UCITS ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both HEAE.L and CNDX.L in my portfolio?

HEAE.L and CNDX.L have a correlation of 0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, HEAE.L or CNDX.L?

On fees, HEAE.L is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, HEAE.L or CNDX.L?

HEAE.L is cheaper with a 0.18% expense ratio, compared with 0.33% for CNDX.L.

What is the main difference between HEAE.L and CNDX.L?

HEAE.L is categorized as Health & Biotech Equities, while CNDX.L is Nasdaq-100. HEAE.L tracks MSCI World/Health Care NR USD, while CNDX.L tracks NASDAQ-100 Index. They also come from different issuers: State Street and iShares. Their fees differ too: 0.18% for HEAE.L and 0.33% for CNDX.L.