GN0M.DE vs. CBUF.DE
GN0M.DE (Global X Genomics & Biotechnology UCITS ETF) and CBUF.DE (iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist) are both Health & Biotech Equities funds - GN0M.DE tracks the Solactive Genomics while CBUF.DE tracks the MSCI World Health Care ESG Reduced Carbon Select 20 35 Capped. Both are passively managed. Over the past 3 years, GN0M.DE returned -1.90%/yr vs 0.62%/yr for CBUF.DE. A 0.51 correlation means they provide meaningful diversification when combined. GN0M.DE charges 0.50%/yr vs 0.18%/yr for CBUF.DE.
Performance
GN0M.DE vs. CBUF.DE - Performance Comparison
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Returns By Period
In the year-to-date period, GN0M.DE achieves a 12.99% return, which is significantly higher than CBUF.DE's -2.22% return.
GN0M.DE
- 1D
- 5.61%
- 1M
- 11.50%
- YTD
- 12.99%
- 6M
- 9.82%
- 1Y
- 55.73%
- 3Y*
- -1.90%
- 5Y*
- —
- 10Y*
- —
CBUF.DE
- 1D
- 2.74%
- 1M
- 3.65%
- YTD
- -2.22%
- 6M
- -1.56%
- 1Y
- 7.33%
- 3Y*
- 0.62%
- 5Y*
- 4.66%
- 10Y*
- —
GN0M.DE vs. CBUF.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
GN0M.DE Global X Genomics & Biotechnology UCITS ETF | 12.99% | 5.67% | -12.40% | -9.04% | -32.50% | -7.90% |
CBUF.DE iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist | -2.22% | 2.56% | 0.75% | 0.33% | 2.09% | 5.19% |
Correlation
The correlation between GN0M.DE and CBUF.DE is 0.55, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.55 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.50 |
Correlation (All Time) Calculated using the full available price history since Nov 12, 2021 | 0.51 |
The correlation between GN0M.DE and CBUF.DE has been stable across timeframes, ranging from 0.50 to 0.55 - a consistent structural relationship.
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Return for Risk
GN0M.DE vs. CBUF.DE — Risk / Return Rank
GN0M.DE
CBUF.DE
GN0M.DE vs. CBUF.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Global X Genomics & Biotechnology UCITS ETF (GN0M.DE) and iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist (CBUF.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| GN0M.DE | CBUF.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.48 | ||
| Sortino ratioReturn per unit of downside risk | +1.95 | ||
| Omega ratioGain probability vs. loss probability | 1.33 | 1.10 | +0.23 |
| Calmar ratioReturn relative to maximum drawdown | 3.32 | 0.68 | +2.65 |
| Martin ratioReturn relative to average drawdown | 8.35 | 1.56 | +6.79 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| GN0M.DE | CBUF.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 2.00 | 0.53 | +1.48 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | — | 0.34 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.34 | 0.44 | -0.78 |
Drawdowns
GN0M.DE vs. CBUF.DE - Drawdown Comparison
The maximum GN0M.DE drawdown since its inception was -67.19%, which is greater than CBUF.DE's maximum drawdown of -25.94%. Use the drawdown chart below to compare losses from any high point for GN0M.DE and CBUF.DE.
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Drawdown Indicators
| GN0M.DE | CBUF.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -67.19% | -25.94% | -41.25% |
Max Drawdown (1Y)Largest decline over 1 year | -16.68% | -10.87% | -5.81% |
Max Drawdown (3Y)Largest decline over 3 years | -48.19% | -21.76% | -26.43% |
Max Drawdown (5Y)Largest decline over 5 years | — | -21.76% | — |
Current DrawdownCurrent decline from peak | -41.03% | -9.66% | -31.37% |
Average DrawdownAverage peak-to-trough decline | -43.13% | -5.65% | -37.48% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.65% | 4.74% | +1.91% |
Volatility
GN0M.DE vs. CBUF.DE - Volatility Comparison
Global X Genomics & Biotechnology UCITS ETF (GN0M.DE) has a higher volatility of 8.15% compared to iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist (CBUF.DE) at 4.98%. This indicates that GN0M.DE's price experiences larger fluctuations and is considered to be riskier than CBUF.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| GN0M.DE | CBUF.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.15% | 4.98% | +3.17% |
Volatility (6M)Calculated over the trailing 6-month period | 19.69% | 9.70% | +9.99% |
Volatility (1Y)Calculated over the trailing 1-year period | 27.68% | 13.98% | +13.70% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 31.49% | 13.60% | +17.89% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 31.49% | 15.36% | +16.13% |
GN0M.DE vs. CBUF.DE - Expense Ratio Comparison
GN0M.DE has a 0.50% expense ratio, which is higher than CBUF.DE's 0.18% expense ratio.
Dividends
GN0M.DE vs. CBUF.DE - Dividend Comparison
GN0M.DE has not paid dividends to shareholders, while CBUF.DE's dividend yield for the trailing twelve months is around 1.08%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
CBUF.DE iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist | 1.08% | 1.06% | 1.02% | 1.16% | 1.09% | 1.05% | 1.27% | 0.10% |
GN0M.DE Global X Genomics & Biotechnology UCITS ETF | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
GN0M.DE and CBUF.DE have a correlation of 0.55, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, CBUF.DE is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.
CBUF.DE is cheaper with a 0.18% expense ratio, compared with 0.50% for GN0M.DE.
GN0M.DE tracks Solactive Genomics, while CBUF.DE tracks MSCI World Health Care ESG Reduced Carbon Select 20 35 Capped. They also come from different issuers: Global X and iShares. Their fees differ too: 0.50% for GN0M.DE and 0.18% for CBUF.DE.
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