FOLD vs. MRVI

Last updated Apr 1, 2026

Compare and contrast key facts about Amicus Therapeutics, Inc. (FOLD) and Maravai LifeSciences Holdings, Inc. (MRVI).

Performance

FOLD vs. MRVI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Amicus Therapeutics, Inc. (FOLD) and Maravai LifeSciences Holdings, Inc. (MRVI). The values are adjusted to include any dividend payments, if applicable.

FOLD vs. MRVI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
FOLD Amicus Therapeutics, Inc.	1.54%	51.17%	-33.62%	16.22%	5.71%	-49.98%	5.05%
MRVI Maravai LifeSciences Holdings, Inc.	-12.92%	-40.37%	-16.79%	-54.23%	-65.85%	49.38%	-6.03%

Fundamentals

Market Cap FOLD : $4.55B MRVI : $410.56M
EPS FOLD : -$0.09 MRVI : -$0.90
PS Ratio FOLD : 7.09 MRVI : 2.20
Total Revenue (TTM) FOLD : $634.21M MRVI : $185.74M
Gross Profit (TTM) FOLD : $561.28M MRVI : $33.99M
EBITDA (TTM) FOLD : $42.38M MRVI : -$164.19M

Returns By Period

In the year-to-date period, FOLD achieves a 1.54% return, which is significantly higher than MRVI's -12.92% return.

FOLD

• 1D: 0.21%
• 1M: 0.63%
• YTD: 1.54%
• 6M: 83.50%
• 1Y: 77.21%
• 3Y*: 9.25%
• 5Y*: 7.53%
• 10Y*: 5.22%

MRVI

• 1D: -1.74%
• 1M: -20.51%
• YTD: -12.92%
• 6M: -1.39%
• 1Y: 28.05%
• 3Y*: -41.33%
• 5Y*: -39.24%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

FOLD vs. MRVI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

FOLD

FOLD Risk / Return Rank: 84
FOLD Sharpe Ratio Rank: 86
FOLD Sortino Ratio Rank: 88
FOLD Omega Ratio Rank: 90
FOLD Calmar Ratio Rank: 80
FOLD Martin Ratio Rank: 77

MRVI

MRVI Risk / Return Rank: 57
MRVI Sharpe Ratio Rank: 56
MRVI Sortino Ratio Rank: 60
MRVI Omega Ratio Rank: 54
MRVI Calmar Ratio Rank: 57
MRVI Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

FOLD vs. MRVI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Amicus Therapeutics, Inc. (FOLD) and Maravai LifeSciences Holdings, Inc. (MRVI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	FOLD	MRVI	Difference
Sharpe ratio Return per unit of total volatility	1.63	0.39	+1.24
Sortino ratio Return per unit of downside risk	2.67	1.15	+1.51
Omega ratio Gain probability vs. loss probability	1.40	1.13	+0.27
Calmar ratio Return relative to maximum drawdown	2.32	0.67	+1.65
Martin ratio Return relative to average drawdown	5.16	1.55	+3.61
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

FOLD vs. MRVI - Sharpe Ratio Comparison

The current FOLD Sharpe Ratio is 1.63, which is higher than the MRVI Sharpe Ratio of 0.39. The chart below compares the historical Sharpe Ratios of FOLD and MRVI, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	FOLD	MRVI	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.63	0.39	+1.24
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.16	-0.53	+0.69
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.09	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.00	-0.49	+0.49

Correlation

The correlation between FOLD and MRVI is 0.25, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

FOLD vs. MRVI - Dividend Comparison

Neither FOLD nor MRVI has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

FOLD vs. MRVI - Drawdown Comparison

The maximum FOLD drawdown since its inception was -89.91%, smaller than the maximum MRVI drawdown of -97.16%. Use the drawdown chart below to compare losses from any high point for FOLD and MRVI.

Drawdown Indicators

	FOLD	MRVI	Difference
Max Drawdown Largest peak-to-trough decline	-89.91%	-97.16%	+7.25%
Max Drawdown (1Y) Largest decline over 1 year	-29.50%	-29.93%	+0.43%
Max Drawdown (5Y) Largest decline over 5 years	-61.16%	-97.16%	+36.00%
Max Drawdown (10Y) Largest decline over 10 years	-77.34%	—	—
Current Drawdown Current decline from peak	-41.90%	-95.33%	+53.43%
Average Drawdown Average peak-to-trough decline	-53.81%	-66.75%	+12.94%
Ulcer Index Depth and duration of drawdowns from previous peaks	13.86%	12.84%	+1.02%

Volatility

FOLD vs. MRVI - Volatility Comparison

The current volatility for Amicus Therapeutics, Inc. (FOLD) is 0.56%, while Maravai LifeSciences Holdings, Inc. (MRVI) has a volatility of 15.37%. This indicates that FOLD experiences smaller price fluctuations and is considered to be less risky than MRVI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	FOLD	MRVI	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.56%	15.37%	-14.81%
Volatility (6M) Calculated over the trailing 6-month period	30.44%	43.81%	-13.37%
Volatility (1Y) Calculated over the trailing 1-year period	47.84%	72.32%	-24.48%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	47.15%	73.79%	-26.64%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	55.54%	73.39%	-17.85%

Financials