FBTTX vs. THISX

Last updated Apr 2, 2026

Compare and contrast key facts about Fidelity Advisor Biotechnology Fund Class M (FBTTX) and T. Rowe Price Health Sciences Fund Class I (THISX).

FBTTX is managed by Fidelity. It was launched on Dec 27, 2000. THISX is an actively managed fund by T. Rowe Price. It was launched on Dec 29, 1995.

Performance

FBTTX vs. THISX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Fidelity Advisor Biotechnology Fund Class M (FBTTX) and T. Rowe Price Health Sciences Fund Class I (THISX). The values are adjusted to include any dividend payments, if applicable.

FBTTX vs. THISX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
FBTTX Fidelity Advisor Biotechnology Fund Class M	2.18%	39.21%	5.08%	10.43%	-8.22%	-3.35%	31.82%	25.39%	-4.19%	23.87%
THISX T. Rowe Price Health Sciences Fund Class I	-6.20%	17.92%	16.75%	3.17%	-12.11%	13.62%	30.35%	38.29%	1.20%	26.96%

Returns By Period

In the year-to-date period, FBTTX achieves a 2.18% return, which is significantly higher than THISX's -6.20% return.

FBTTX

• 1D: 5.09%
• 1M: -0.77%
• YTD: 2.18%
• 6M: 15.39%
• 1Y: 55.03%
• 3Y*: 20.14%
• 5Y*: 8.63%
• 10Y*: 11.54%

THISX

• 1D: 3.78%
• 1M: -4.80%
• YTD: -6.20%
• 6M: 6.21%
• 1Y: 12.76%
• 3Y*: 10.88%
• 5Y*: 5.84%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

FBTTX vs. THISX - Expense Ratio Comparison

FBTTX has a 1.28% expense ratio, which is higher than THISX's 0.67% expense ratio.

FBTTX

Fidelity Advisor Biotechnology Fund Class M

THISX

T. Rowe Price Health Sciences Fund Class I

Return for Risk

FBTTX vs. THISX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

FBTTX

FBTTX Risk / Return Rank: 89
FBTTX Sharpe Ratio Rank: 90
FBTTX Sortino Ratio Rank: 88
FBTTX Omega Ratio Rank: 79
FBTTX Calmar Ratio Rank: 93
FBTTX Martin Ratio Rank: 93

THISX

THISX Risk / Return Rank: 17
THISX Sharpe Ratio Rank: 16
THISX Sortino Ratio Rank: 17
THISX Omega Ratio Rank: 14
THISX Calmar Ratio Rank: 19
THISX Martin Ratio Rank: 17

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

FBTTX vs. THISX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Fidelity Advisor Biotechnology Fund Class M (FBTTX) and T. Rowe Price Health Sciences Fund Class I (THISX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	FBTTX	THISX	Difference
Sharpe ratio Return per unit of total volatility	1.92	0.57	+1.36
Sortino ratio Return per unit of downside risk	2.52	0.91	+1.61
Omega ratio Gain probability vs. loss probability	1.32	1.12	+0.21
Calmar ratio Return relative to maximum drawdown	3.13	0.79	+2.34
Martin ratio Return relative to average drawdown	12.48	2.38	+10.09
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

FBTTX vs. THISX - Sharpe Ratio Comparison

The current FBTTX Sharpe Ratio is 1.92, which is higher than the THISX Sharpe Ratio of 0.57. The chart below compares the historical Sharpe Ratios of FBTTX and THISX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	FBTTX	THISX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.92	0.57	+1.36
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.37	0.32	+0.05
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.47	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.30	0.65	-0.35

Correlation

The correlation between FBTTX and THISX is 0.85, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.

Dividends

FBTTX vs. THISX - Dividend Comparison

FBTTX's dividend yield for the trailing twelve months is around 1.50%, less than THISX's 13.06% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
FBTTX Fidelity Advisor Biotechnology Fund Class M	1.50%	1.53%	6.41%	0.93%	0.00%	21.60%	8.79%	7.10%	2.64%	0.00%	0.00%	5.42%
THISX T. Rowe Price Health Sciences Fund Class I	13.06%	12.25%	26.10%	5.20%	1.76%	7.62%	7.25%	12.58%	6.70%	7.55%	0.00%	0.00%

Drawdowns

FBTTX vs. THISX - Drawdown Comparison

The maximum FBTTX drawdown since its inception was -63.75%, which is greater than THISX's maximum drawdown of -28.97%. Use the drawdown chart below to compare losses from any high point for FBTTX and THISX.

Drawdown Indicators

	FBTTX	THISX	Difference
Max Drawdown Largest peak-to-trough decline	-63.75%	-28.97%	-34.78%
Max Drawdown (1Y) Largest decline over 1 year	-13.58%	-12.78%	-0.80%
Max Drawdown (5Y) Largest decline over 5 years	-36.64%	-27.53%	-9.11%
Max Drawdown (10Y) Largest decline over 10 years	-39.04%	—	—
Current Drawdown Current decline from peak	-2.61%	-9.15%	+6.54%
Average Drawdown Average peak-to-trough decline	-21.95%	-7.18%	-14.77%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.72%	4.25%	-0.53%

Volatility

FBTTX vs. THISX - Volatility Comparison

Fidelity Advisor Biotechnology Fund Class M (FBTTX) has a higher volatility of 9.37% compared to T. Rowe Price Health Sciences Fund Class I (THISX) at 6.69%. This indicates that FBTTX's price experiences larger fluctuations and is considered to be riskier than THISX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	FBTTX	THISX	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.37%	6.69%	+2.68%
Volatility (6M) Calculated over the trailing 6-month period	17.02%	11.31%	+5.71%
Volatility (1Y) Calculated over the trailing 1-year period	25.99%	18.75%	+7.24%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	23.31%	18.35%	+4.96%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	24.58%	20.02%	+4.56%