THISX vs. TTMIX

Last updated Aug 1, 2026

THISX (T. Rowe Price Health Sciences Fund Class I) and TTMIX (T. Rowe Price Total Return Fund Class I) are both mutual funds - THISX is a Health & Biotech Equities fund actively managed by T. Rowe Price, while TTMIX is a Global Allocation fund managed by T. Rowe Price. Over the past 5 years, THISX returned 6.65%/yr vs 2.29%/yr for TTMIX. Their 0.63 correlation means they have sometimes moved together and sometimes differently. THISX charges 0.67%/yr vs 0.37%/yr for TTMIX.

Performance

THISX vs. TTMIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in T. Rowe Price Health Sciences Fund Class I (THISX) and T. Rowe Price Total Return Fund Class I (TTMIX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, THISX achieves a 8.73% return, which is significantly higher than TTMIX's -5.87% return.

THISX

• 1D: -0.35%
• 1M: -1.26%
• 6M: 9.79%
• YTD: 8.73%
• 1Y: 33.49%
• 3Y*: 15.21%
• 5Y*: 6.65%
• 10Y*: —
• ALL TIME*: 14.23%

TTMIX

• 1D: 0.85%
• 1M: -5.00%
• 6M: -4.11%
• YTD: -5.87%
• 1Y: -6.48%
• 3Y*: 14.51%
• 5Y*: 2.29%
• 10Y*: 13.22%
• ALL TIME*: 13.86%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
THISX T. Rowe Price Health Sciences Fund Class I	$0.00	$0.00	$0.00
TTMIX T. Rowe Price Total Return Fund Class I	$0.00	$0.00	$0.00

THISX vs. TTMIX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
THISX T. Rowe Price Health Sciences Fund Class I	8.73%	17.92%	16.75%	3.17%	-12.11%	13.62%	30.35%	38.29%	1.20%	26.96%
TTMIX T. Rowe Price Total Return Fund Class I	-5.87%	6.97%	38.33%	39.41%	-40.85%	9.92%	53.86%	35.84%	-1.73%	33.14%

Correlation

The correlation between THISX and TTMIX is 0.23, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.23
Correlation (3Y) Balances recent behavior with more history.	0.43
Correlation (5Y) Shows whether the relationship held over a longer period.	0.59
Correlation (All Time) Calculated using the full available price history since Jan 3, 2017	0.63

Over the past year, the correlation between THISX and TTMIX has dropped to 0.23 - well below their long-term average of 0.63, suggesting their price drivers have been diverging.

Return for Risk

THISX vs. TTMIX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

THISX

THISX Risk / Return Rank: 72
THISX Sharpe Ratio Rank: 81
THISX Sortino Ratio Rank: 81
THISX Omega Ratio Rank: 74
THISX Calmar Ratio Rank: 76
THISX Martin Ratio Rank: 50

TTMIX

TTMIX Risk / Return Rank: 1
TTMIX Sharpe Ratio Rank: 1
TTMIX Sortino Ratio Rank: 1
TTMIX Omega Ratio Rank: 2
TTMIX Calmar Ratio Rank: 1
TTMIX Martin Ratio Rank: 1

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

THISX vs. TTMIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for T. Rowe Price Health Sciences Fund Class I (THISX) and T. Rowe Price Total Return Fund Class I (TTMIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	THISX	TTMIX	Difference
Sharpe ratio: Return per unit of total volatility	1.97	-0.45	+2.42
Sortino ratio: Return per unit of downside risk	2.88	-0.53	+3.41
Omega ratio: Gain probability vs. loss probability	1.33	0.94	+0.40
Calmar ratio: Return relative to maximum drawdown	2.52	-0.42	+2.94
Martin ratio: Return relative to average drawdown	7.04	-0.91	+7.95

THISX vs. TTMIX - Sharpe Ratio Comparison

The current THISX Sharpe Ratio is 1.97, which is higher than the TTMIX Sharpe Ratio of -0.45. The chart below compares the historical Sharpe Ratios of THISX and TTMIX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

THISX vs. TTMIX - Drawdown Comparison

The maximum THISX drawdown since its inception was -28.97%, smaller than the maximum TTMIX drawdown of -47.11%. Use the drawdown chart below to compare losses from any high point for THISX and TTMIX.

Drawdown Indicators

	THISX	TTMIX	Difference
Max Drawdown Largest peak-to-trough decline	-28.97%	-47.11%	+18.14%
Max Drawdown (1Y) Largest decline over 1 year	-12.78%	-17.25%	+4.47%
Max Drawdown (3Y) Largest decline over 3 years	-15.80%	-20.68%	+4.88%
Max Drawdown (5Y) Largest decline over 5 years	-27.53%	-47.11%	+19.58%
Max Drawdown (10Y) Largest decline over 10 years	—	-47.11%	—
Current Drawdown Current decline from peak	-2.22%	-13.27%	+11.05%
Average Drawdown Average peak-to-trough decline	-7.10%	-10.25%	+3.15%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.56%	8.00%	-3.44%

Volatility

THISX vs. TTMIX - Volatility Comparison

The current volatility for T. Rowe Price Health Sciences Fund Class I (THISX) is 5.14%, while T. Rowe Price Total Return Fund Class I (TTMIX) has a volatility of 5.72%. This indicates that THISX experiences smaller price fluctuations and is considered to be less risky than TTMIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	THISX	TTMIX	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.14%	5.72%	-0.58%
Volatility (6M) Calculated over the trailing 6-month period	12.96%	13.45%	-0.49%
Volatility (1Y) Calculated over the trailing 1-year period	16.35%	16.16%	+0.19%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	18.63%	21.46%	-2.83%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	19.95%	20.82%	-0.87%

THISX vs. TTMIX - Expense Ratio Comparison

THISX has a 0.67% expense ratio, which is higher than TTMIX's 0.37% expense ratio.

Dividends

THISX vs. TTMIX - Dividend Comparison

THISX's dividend yield for the trailing twelve months is around 11.27%, less than TTMIX's 26.85% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
THISX T. Rowe Price Health Sciences Fund Class I	11.27%	12.25%	26.10%	5.20%	1.76%	7.62%	7.25%	12.58%	6.70%	7.55%	0.00%
TTMIX T. Rowe Price Total Return Fund Class I	26.85%	25.27%	7.45%	7.80%	17.43%	8.53%	5.27%	2.44%	1.41%	2.47%	2.23%

Frequently Asked Questions

Can I hold both THISX and TTMIX in my portfolio?

THISX and TTMIX have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, THISX or TTMIX?

TTMIX has higher volatility (5.72%) compared to THISX (5.14%). In terms of maximum drawdown, THISX dropped -28.97% vs TTMIX's -47.11%.

Which has better risk-adjusted returns?

THISX currently has the higher Sharpe Ratio (1.97 vs -0.45), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.