ESIH.DE vs. 2B78.DE
ESIH.DE (iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc)) and 2B78.DE (iShares Healthcare Innovation UCITS ETF) are both Health & Biotech Equities funds from iShares - ESIH.DE tracks the MSCI World/Health Care NR USD while 2B78.DE tracks the iSTOXX® FactSet Breakthrough Healthcare. Both are passively managed. Over the past 5 years, ESIH.DE returned 5.74%/yr vs -1.74%/yr for 2B78.DE. A 0.56 correlation means they provide meaningful diversification when combined. ESIH.DE charges 0.18%/yr vs 0.40%/yr for 2B78.DE.
Performance
ESIH.DE vs. 2B78.DE - Performance Comparison
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Returns By Period
In the year-to-date period, ESIH.DE achieves a -2.35% return, which is significantly lower than 2B78.DE's -2.07% return.
ESIH.DE
- 1D
- 3.10%
- 1M
- 0.16%
- YTD
- -2.35%
- 6M
- -1.01%
- 1Y
- 6.11%
- 3Y*
- 2.72%
- 5Y*
- 5.74%
- 10Y*
- —
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
ESIH.DE vs. 2B78.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
ESIH.DE iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc) | -2.35% | 7.95% | 4.09% | 7.63% | -4.59% | 25.93% | -0.69% |
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 7.59% |
Correlation
The correlation between ESIH.DE and 2B78.DE is 0.64, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.64 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.56 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.56 |
Correlation (All Time) Calculated using the full available price history since Nov 23, 2020 | 0.56 |
The correlation between ESIH.DE and 2B78.DE has been stable across timeframes, ranging from 0.56 to 0.64 - a consistent structural relationship.
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Return for Risk
ESIH.DE vs. 2B78.DE — Risk / Return Rank
ESIH.DE
2B78.DE
ESIH.DE vs. 2B78.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc) (ESIH.DE) and iShares Healthcare Innovation UCITS ETF (2B78.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| ESIH.DE | 2B78.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.60 | ||
| Sortino ratioReturn per unit of downside risk | -0.81 | ||
| Omega ratioGain probability vs. loss probability | 1.07 | 1.17 | -0.09 |
| Calmar ratioReturn relative to maximum drawdown | 0.47 | 1.24 | -0.77 |
| Martin ratioReturn relative to average drawdown | 1.05 | 3.07 | -2.02 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| ESIH.DE | 2B78.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.35 | 0.95 | -0.60 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.36 | -0.10 | +0.45 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.41 | 0.31 | +0.10 |
Drawdowns
ESIH.DE vs. 2B78.DE - Drawdown Comparison
The maximum ESIH.DE drawdown since its inception was -26.69%, smaller than the maximum 2B78.DE drawdown of -38.58%. Use the drawdown chart below to compare losses from any high point for ESIH.DE and 2B78.DE.
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Drawdown Indicators
| ESIH.DE | 2B78.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -26.69% | -38.58% | +11.89% |
Max Drawdown (1Y)Largest decline over 1 year | -12.82% | -12.05% | -0.77% |
Max Drawdown (3Y)Largest decline over 3 years | -26.69% | -25.32% | -1.37% |
Max Drawdown (5Y)Largest decline over 5 years | -26.69% | -36.99% | +10.30% |
Current DrawdownCurrent decline from peak | -10.96% | -19.03% | +8.07% |
Average DrawdownAverage peak-to-trough decline | -7.24% | -14.36% | +7.12% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 5.75% | 4.86% | +0.89% |
Volatility
ESIH.DE vs. 2B78.DE - Volatility Comparison
iShares MSCI Europe Health Care Sector UCITS ETF EUR (Acc) (ESIH.DE) has a higher volatility of 5.87% compared to iShares Healthcare Innovation UCITS ETF (2B78.DE) at 3.74%. This indicates that ESIH.DE's price experiences larger fluctuations and is considered to be riskier than 2B78.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ESIH.DE | 2B78.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 5.87% | 3.74% | +2.13% |
Volatility (6M)Calculated over the trailing 6-month period | 11.96% | 10.97% | +0.99% |
Volatility (1Y)Calculated over the trailing 1-year period | 17.18% | 15.67% | +1.51% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 15.86% | 17.91% | -2.05% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 15.61% | 18.79% | -3.18% |
ESIH.DE vs. 2B78.DE - Expense Ratio Comparison
ESIH.DE has a 0.18% expense ratio, which is lower than 2B78.DE's 0.40% expense ratio.
Dividends
ESIH.DE vs. 2B78.DE - Dividend Comparison
Neither ESIH.DE nor 2B78.DE has paid dividends to shareholders.
Frequently Asked Questions
ESIH.DE and 2B78.DE have a correlation of 0.64, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, ESIH.DE is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.
ESIH.DE is cheaper with a 0.18% expense ratio, compared with 0.40% for 2B78.DE.
ESIH.DE tracks MSCI World/Health Care NR USD, while 2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare. Their fees differ too: 0.18% for ESIH.DE and 0.40% for 2B78.DE.
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