EQ vs. ONL

Last updated Jun 3, 2026

EQ (Equillium Inc) and ONL (Orion Office REIT Inc.) are both stocks. EQ operates in Biotechnology (Healthcare), while ONL operates in REIT - Office (Real Estate). Over the past 3 years, EQ returned 64.24%/yr vs -16.33%/yr for ONL. At a 0.08 correlation, their price movements are largely independent.

Performance

EQ vs. ONL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Equillium Inc (EQ) and Orion Office REIT Inc. (ONL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, EQ achieves a 80.00% return, which is significantly higher than ONL's 28.74% return.

EQ

• 1D: -9.42%
• 1M: 34.13%
• YTD: 80.00%
• 6M: 224.68%
• 1Y: 662.30%
• 3Y*: 64.24%
• 5Y*: -16.15%
• 10Y*: —

ONL

• 1D: -2.37%
• 1M: 0.35%
• YTD: 28.74%
• 6M: 35.92%
• 1Y: 47.79%
• 3Y*: -16.33%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

EQ vs. ONL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
EQ Equillium Inc	80.00%	107.16%	3.49%	-31.79%	-71.88%	-32.80%
ONL Orion Office REIT Inc.	28.74%	-36.91%	-27.43%	-28.36%	-52.44%	-12.35%

Correlation

The correlation between EQ and ONL is -0.01, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.01
Correlation (3Y) Calculated over the trailing 3-year period	0.10
Correlation (All Time) Calculated using the full available price history since Nov 16, 2021	0.08

The correlation between EQ and ONL shifts across timeframes, from -0.01 (1 year) to 0.10 (3 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap EQ : $268.62M ONL : $162.91M
EPS EQ : -$0.29 ONL : -$2.55
PB Ratio EQ : 4.52 ONL : 0.27
Total Revenue (TTM) EQ : $0.00 ONL : $145.92M
Gross Profit (TTM) EQ : -$83.00K ONL : $82.76M
EBITDA (TTM) EQ : -$19.95M ONL : -$71.64M

Return for Risk

EQ vs. ONL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

EQ

EQ Risk / Return Rank: 96
EQ Sharpe Ratio Rank: 97
EQ Sortino Ratio Rank: 96
EQ Omega Ratio Rank: 93
EQ Calmar Ratio Rank: 97
EQ Martin Ratio Rank: 96

ONL

ONL Risk / Return Rank: 67
ONL Sharpe Ratio Rank: 69
ONL Sortino Ratio Rank: 68
ONL Omega Ratio Rank: 67
ONL Calmar Ratio Rank: 66
ONL Martin Ratio Rank: 65

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

EQ vs. ONL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Equillium Inc (EQ) and Orion Office REIT Inc. (ONL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	EQ	ONL	Difference
Sharpe ratio Return per unit of total volatility	4.03	0.92	+3.11
Sortino ratio Return per unit of downside risk	4.48	1.66	+2.82
Omega ratio Gain probability vs. loss probability	1.52	1.21	+0.31
Calmar ratio Return relative to maximum drawdown	10.65	1.30	+9.34
Martin ratio Return relative to average drawdown	23.47	2.73	+20.74
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

EQ vs. ONL - Sharpe Ratio Comparison

The current EQ Sharpe Ratio is 4.03, which is higher than the ONL Sharpe Ratio of 0.92. The chart below compares the historical Sharpe Ratios of EQ and ONL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	EQ	ONL	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	4.03	0.92	+3.11
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.14	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.07	-0.66	+0.59

Drawdowns

EQ vs. ONL - Drawdown Comparison

The maximum EQ drawdown since its inception was -98.91%, which is greater than ONL's maximum drawdown of -91.12%. Use the drawdown chart below to compare losses from any high point for EQ and ONL.

Drawdown Indicators

	EQ	ONL	Difference
Max Drawdown Largest peak-to-trough decline	-98.91%	-91.12%	-7.79%
Max Drawdown (1Y) Largest decline over 1 year	-57.79%	-36.80%	-20.99%
Max Drawdown (3Y) Largest decline over 3 years	-90.33%	-74.20%	-16.13%
Max Drawdown (5Y) Largest decline over 5 years	-96.20%	—	—
Current Drawdown Current decline from peak	-89.47%	-82.56%	-6.91%
Average Drawdown Average peak-to-trough decline	-84.98%	-68.51%	-16.47%
Ulcer Index Depth and duration of drawdowns from previous peaks	26.22%	17.56%	+8.66%

Volatility

EQ vs. ONL - Volatility Comparison

Equillium Inc (EQ) has a higher volatility of 38.62% compared to Orion Office REIT Inc. (ONL) at 8.17%. This indicates that EQ's price experiences larger fluctuations and is considered to be riskier than ONL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	EQ	ONL	Difference
Volatility (1M) Calculated over the trailing 1-month period	38.62%	8.17%	+30.45%
Volatility (6M) Calculated over the trailing 6-month period	79.07%	37.82%	+41.25%
Volatility (1Y) Calculated over the trailing 1-year period	165.88%	52.70%	+113.18%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	114.75%	48.31%	+66.44%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	288.95%	48.31%	+240.64%

Dividends

EQ vs. ONL - Dividend Comparison

EQ has not paid dividends to shareholders, while ONL's dividend yield for the trailing twelve months is around 2.78%.

Position	TTM	2025	2024	2023	2022
EQ Equillium Inc	0.00%	0.00%	0.00%	0.00%	0.00%
ONL Orion Office REIT Inc.	2.78%	3.54%	10.78%	6.99%	4.68%

Financials

Frequently Asked Questions

Can I hold both EQ and ONL in my portfolio?

EQ and ONL have a correlation of -0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, EQ or ONL?

EQ has higher volatility (38.62%) compared to ONL (8.17%). In terms of maximum drawdown, EQ dropped -98.91% vs ONL's -91.12%.

Which has better risk-adjusted returns?

EQ currently has the higher Sharpe Ratio (4.03 vs 0.92), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.