EPSB vs. MEDI

Last updated Jun 4, 2026

EPSB (Harbor SMID Cap Core ETF) and MEDI (Harbor Health Care ETF) are both exchange-traded funds - EPSB is a Small Cap Blend Equities fund actively managed by Harbor, while MEDI is a Health & Biotech Equities fund actively managed by Harbor. Both are actively managed. Over the past year, EPSB returned 29.37% vs 18.27% for MEDI. At a 0.39 correlation, their price movements are largely independent. EPSB charges 0.88%/yr vs 0.80%/yr for MEDI.

Performance

EPSB vs. MEDI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Harbor SMID Cap Core ETF (EPSB) and Harbor Health Care ETF (MEDI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, EPSB achieves a 18.61% return, which is significantly higher than MEDI's -4.02% return.

EPSB

• 1D: 0.44%
• 1M: 2.40%
• YTD: 18.61%
• 6M: 19.57%
• 1Y: 29.37%
• 3Y*: —
• 5Y*: —
• 10Y*: —

MEDI

• 1D: 1.06%
• 1M: -0.93%
• YTD: -4.02%
• 6M: -4.83%
• 1Y: 18.27%
• 3Y*: 12.46%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

EPSB vs. MEDI - Yearly Performance Comparison

	2026 (YTD)	2025
EPSB Harbor SMID Cap Core ETF	18.61%	13.67%
MEDI Harbor Health Care ETF	-4.02%	21.26%

Correlation

The correlation between EPSB and MEDI is 0.39, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.39
Correlation (All Time) Calculated using the full available price history since May 5, 2025	0.39

EPSB vs. MEDI - Sectors Allocation Comparison

Sectors	EPSB	MEDI
Industrials	29.9%	-
Technology	22.6%	-
Financial Services	13.8%	-
Consumer Cyclical	7.9%	-
Basic Materials	7.1%	-
Healthcare	6.3%	100.0%
Real Estate	6.1%	-
Energy	3.2%	-
Utilities	3.1%	-
Communication Services	-	-
Consumer Defensive	-	-

Return for Risk

EPSB vs. MEDI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

EPSB

EPSB Risk / Return Rank: 64
EPSB Sharpe Ratio Rank: 60
EPSB Sortino Ratio Rank: 65
EPSB Omega Ratio Rank: 57
EPSB Calmar Ratio Rank: 71
EPSB Martin Ratio Rank: 66

MEDI

MEDI Risk / Return Rank: 26
MEDI Sharpe Ratio Rank: 26
MEDI Sortino Ratio Rank: 27
MEDI Omega Ratio Rank: 24
MEDI Calmar Ratio Rank: 25
MEDI Martin Ratio Rank: 26

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

EPSB vs. MEDI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Harbor SMID Cap Core ETF (EPSB) and Harbor Health Care ETF (MEDI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	EPSB	MEDI	Difference
Sharpe ratio: Return per unit of total volatility	1.98	0.93	+1.05
Sortino ratio: Return per unit of downside risk	2.97	1.46	+1.51
Omega ratio: Gain probability vs. loss probability	1.34	1.17	+0.18
Calmar ratio: Return relative to maximum drawdown	3.49	1.20	+2.29
Martin ratio: Return relative to average drawdown	11.84	3.59	+8.25
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

EPSB vs. MEDI - Sharpe Ratio Comparison

The current EPSB Sharpe Ratio is 1.98, which is higher than the MEDI Sharpe Ratio of 0.93. The chart below compares the historical Sharpe Ratios of EPSB and MEDI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	EPSB	MEDI	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.98	0.93	+1.05
Sharpe Ratio (All Time) Calculated using the full available price history	2.08	0.74	+1.34

Drawdowns

EPSB vs. MEDI - Drawdown Comparison

The maximum EPSB drawdown since its inception was -8.46%, smaller than the maximum MEDI drawdown of -19.24%. Use the drawdown chart below to compare losses from any high point for EPSB and MEDI.

Drawdown Indicators

	EPSB	MEDI	Difference
Max Drawdown Largest peak-to-trough decline	-8.46%	-19.24%	+10.78%
Max Drawdown (1Y) Largest decline over 1 year	-8.46%	-15.34%	+6.88%
Max Drawdown (3Y) Largest decline over 3 years	—	-19.24%	—
Current Drawdown Current decline from peak	-0.31%	-8.01%	+7.70%
Average Drawdown Average peak-to-trough decline	-1.58%	-4.28%	+2.70%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.49%	5.10%	-2.61%

Volatility

EPSB vs. MEDI - Volatility Comparison

The current volatility for Harbor SMID Cap Core ETF (EPSB) is 4.44%, while Harbor Health Care ETF (MEDI) has a volatility of 6.02%. This indicates that EPSB experiences smaller price fluctuations and is considered to be less risky than MEDI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	EPSB	MEDI	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.44%	6.02%	-1.58%
Volatility (6M) Calculated over the trailing 6-month period	10.87%	15.42%	-4.55%
Volatility (1Y) Calculated over the trailing 1-year period	15.00%	19.82%	-4.82%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	15.38%	18.63%	-3.25%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	15.38%	18.63%	-3.25%

EPSB vs. MEDI - Expense Ratio Comparison

EPSB has a 0.88% expense ratio, which is higher than MEDI's 0.80% expense ratio.

Dividends

EPSB vs. MEDI - Dividend Comparison

EPSB's dividend yield for the trailing twelve months is around 1.15%, more than MEDI's 0.29% yield.

Position	TTM	2025	2024	2023
EPSB Harbor SMID Cap Core ETF	1.15%	1.36%	0.00%	0.00%
MEDI Harbor Health Care ETF	0.29%	0.28%	0.54%	1.86%

Frequently Asked Questions

Can I hold both EPSB and MEDI in my portfolio?

EPSB and MEDI have a correlation of 0.39, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, EPSB or MEDI?

MEDI has higher volatility (6.02%) compared to EPSB (4.44%). In terms of maximum drawdown, EPSB dropped -8.46% vs MEDI's -19.24%.

Which ETF is better, EPSB or MEDI?

On 1-year performance, EPSB leads with 29.37% vs 18.27% for MEDI. On fees, MEDI is cheaper at 0.80% per year. On volatility, EPSB has been the lower-risk option at 4.44%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, EPSB or MEDI?

Over the 1-year period, EPSB has performed better with a 29.37% return vs 18.27%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, EPSB or MEDI?

MEDI is cheaper with a 0.80% expense ratio, compared with 0.88% for EPSB.

Which ETF pays a higher dividend yield, EPSB or MEDI?

EPSB has the higher dividend yield at 1.15%, compared with 0.29% for MEDI.

What is the main difference between EPSB and MEDI?

EPSB is categorized as Small Cap Blend Equities, while MEDI is Health & Biotech Equities. Their fees differ too: 0.88% for EPSB and 0.80% for MEDI.

Which has better risk-adjusted returns?

EPSB currently has the higher Sharpe Ratio (1.98 vs 0.93), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.