ENTX vs. VIR

Last updated Aug 1, 2026

ENTX (Entera Bio Ltd) and VIR (Vir Biotechnology, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, ENTX returned -10.27%/yr vs -24.65%/yr for VIR. Their 0.13 correlation means their historical movements had little consistent relationship.

Performance

ENTX vs. VIR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Entera Bio Ltd (ENTX) and Vir Biotechnology, Inc. (VIR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ENTX achieves a 54.12% return, which is significantly higher than VIR's 43.62% return.

ENTX

• 1D: 1.36%
• 1M: 80.12%
• 6M: 118.25%
• YTD: 54.12%
• 1Y: 53.33%
• 3Y*: 55.19%
• 5Y*: -10.27%
• 10Y*: —
• ALL TIME*: -10.45%

VIR

• 1D: -2.70%
• 1M: -13.75%
• 6M: 16.40%
• YTD: 43.62%
• 1Y: 72.17%
• 3Y*: -15.28%
• 5Y*: -24.65%
• 10Y*: —
• ALL TIME*: -8.75%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ENTX Entera Bio Ltd	$35.47M	$17.12M	$7.21M
VIR Vir Biotechnology, Inc.	$13.61M	$14.70M	$17.41M

ENTX vs. VIR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
ENTX Entera Bio Ltd	54.12%	-8.49%	253.33%	-17.81%	-74.07%	160.65%	-49.53%	7.54%
VIR Vir Biotechnology, Inc.	43.62%	-17.85%	-27.04%	-60.25%	-39.55%	56.35%	112.96%	-22.14%

Correlation

The correlation between ENTX and VIR is 0.24, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.24
Correlation (3Y) Balances recent behavior with more history.	0.19
Correlation (5Y) Shows whether the relationship held over a longer period.	0.17
Correlation (All Time) Calculated using the full available price history since Oct 11, 2019	0.13

The correlation between ENTX and VIR shifts across timeframes, from 0.13 (all time) to 0.24 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ENTX : $147.38M VIR : $1.46B
EPS ENTX : -$0.11 VIR : -$3.12
PB Ratio ENTX : 13.36 VIR : 1.57
Total Revenue (TTM) ENTX : $0.00 VIR : $65.50M
Gross Profit (TTM) ENTX : -$15.00K VIR : $183.11M
EBITDA (TTM) ENTX : -$12.42M VIR : -$448.10M

Return for Risk

ENTX vs. VIR — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ENTX

ENTX Risk / Return Rank: 67
ENTX Sharpe Ratio Rank: 61
ENTX Sortino Ratio Rank: 78
ENTX Omega Ratio Rank: 73
ENTX Calmar Ratio Rank: 64
ENTX Martin Ratio Rank: 59

VIR

VIR Risk / Return Rank: 79
VIR Sharpe Ratio Rank: 76
VIR Sortino Ratio Rank: 78
VIR Omega Ratio Rank: 74
VIR Calmar Ratio Rank: 85
VIR Martin Ratio Rank: 83

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ENTX vs. VIR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Entera Bio Ltd (ENTX) and Vir Biotechnology, Inc. (VIR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ENTX	VIR	Difference
Sharpe ratio: Return per unit of total volatility	0.43	1.03	-0.60
Sortino ratio: Return per unit of downside risk	1.94	1.89	+0.05
Omega ratio: Gain probability vs. loss probability	1.21	1.22	0.00
Calmar ratio: Return relative to maximum drawdown	0.81	2.78	-1.97
Martin ratio: Return relative to average drawdown	1.25	6.37	-5.11

ENTX vs. VIR - Sharpe Ratio Comparison

The current ENTX Sharpe Ratio is 0.43, which is lower than the VIR Sharpe Ratio of 1.03. The chart below compares the historical Sharpe Ratios of ENTX and VIR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ENTX vs. VIR - Drawdown Comparison

The maximum ENTX drawdown since its inception was -93.15%, roughly equal to the maximum VIR drawdown of -94.85%. Use the drawdown chart below to compare losses from any high point for ENTX and VIR.

Drawdown Indicators

	ENTX	VIR	Difference
Max Drawdown Largest peak-to-trough decline	-93.15%	-94.85%	+1.70%
Max Drawdown (1Y) Largest decline over 1 year	-68.15%	-25.61%	-42.54%
Max Drawdown (3Y) Largest decline over 3 years	-68.15%	-68.58%	+0.43%
Max Drawdown (5Y) Largest decline over 5 years	-91.26%	-92.15%	+0.89%
Current Drawdown Current decline from peak	-59.04%	-89.58%	+30.54%
Average Drawdown Average peak-to-trough decline	-68.20%	-68.14%	-0.06%
Ulcer Index Depth and duration of drawdowns from previous peaks	44.00%	11.16%	+32.84%

Volatility

ENTX vs. VIR - Volatility Comparison

Entera Bio Ltd (ENTX) has a higher volatility of 70.79% compared to Vir Biotechnology, Inc. (VIR) at 12.38%. This indicates that ENTX's price experiences larger fluctuations and is considered to be riskier than VIR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ENTX	VIR	Difference
Volatility (1M) Calculated over the trailing 1-month period	70.79%	12.38%	+58.41%
Volatility (6M) Calculated over the trailing 6-month period	97.26%	45.20%	+52.06%
Volatility (1Y) Calculated over the trailing 1-year period	128.59%	69.13%	+59.46%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	96.95%	72.66%	+24.29%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	114.64%	95.40%	+19.24%

Dividends

ENTX vs. VIR - Dividend Comparison

Neither ENTX nor VIR has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ENTX and VIR in my portfolio?

ENTX and VIR have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ENTX or VIR?

ENTX has higher volatility (70.79%) compared to VIR (12.38%). In terms of maximum drawdown, ENTX dropped -93.15% vs VIR's -94.85%.

Which has better risk-adjusted returns?

VIR currently has the higher Sharpe Ratio (1.03 vs 0.43), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.