DRUG.AX vs. F100.AX

Last updated Jul 18, 2026

DRUG.AX (Betashares Global Healthcare Currency Hedged ETF) and F100.AX (Betashares FTSE 100 ETF) are both exchange-traded funds - DRUG.AX is a Health & Biotech Equities fund tracking the Nasdaq Global ex-Australia Healthcare Hedged AUD Index, while F100.AX is a Global Equities fund tracking the FTSE 100 Index. Both are passively managed. Over the past 5 years, DRUG.AX returned 4.03%/yr vs 11.19%/yr for F100.AX. At a 0.48 correlation, their price movements are largely independent. DRUG.AX charges 0.57%/yr vs 0.45%/yr for F100.AX.

Performance

DRUG.AX vs. F100.AX - Performance Comparison

The chart below illustrates the hypothetical performance of a A$10,000 investment in Betashares Global Healthcare Currency Hedged ETF (DRUG.AX) and Betashares FTSE 100 ETF (F100.AX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, DRUG.AX achieves a 1.49% return, which is significantly lower than F100.AX's 2.19% return.

DRUG.AX

• 1D: 1.89%
• 1M: 5.32%
• 6M: 0.23%
• YTD: 1.49%
• 1Y: 17.07%
• 3Y*: 6.21%
• 5Y*: 4.03%
• 10Y*: —

F100.AX

• 1D: 0.40%
• 1M: 2.19%
• 6M: 0.99%
• YTD: 2.19%
• 1Y: 11.24%
• 3Y*: 14.98%
• 5Y*: 11.19%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

DRUG.AX vs. F100.AX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
DRUG.AX Betashares Global Healthcare Currency Hedged ETF	1.49%	11.83%	1.82%	0.76%	-3.68%	23.60%	4.75%	10.26%
F100.AX Betashares FTSE 100 ETF	2.19%	25.77%	14.12%	11.00%	-1.20%	21.76%	-16.05%	7.82%

Correlation

The correlation between DRUG.AX and F100.AX is 0.51, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.51
Correlation (3Y) Calculated over the trailing 3-year period	0.45
Correlation (5Y) Calculated over the trailing 5-year period	0.44
Correlation (All Time) Calculated using the full available price history since Jul 12, 2019	0.48

The correlation between DRUG.AX and F100.AX has been stable across timeframes, ranging from 0.44 to 0.51 - a consistent structural relationship.

Return for Risk

DRUG.AX vs. F100.AX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DRUG.AX

DRUG.AX Risk / Return Rank: 38
DRUG.AX Sharpe Ratio Rank: 39
DRUG.AX Sortino Ratio Rank: 43
DRUG.AX Omega Ratio Rank: 38
DRUG.AX Calmar Ratio Rank: 39
DRUG.AX Martin Ratio Rank: 33

F100.AX

F100.AX Risk / Return Rank: 33
F100.AX Sharpe Ratio Rank: 35
F100.AX Sortino Ratio Rank: 35
F100.AX Omega Ratio Rank: 32
F100.AX Calmar Ratio Rank: 32
F100.AX Martin Ratio Rank: 33

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DRUG.AX vs. F100.AX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Betashares Global Healthcare Currency Hedged ETF (DRUG.AX) and Betashares FTSE 100 ETF (F100.AX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	DRUG.AX	F100.AX	Difference
Sharpe ratio: Return per unit of total volatility	1.07	0.96	+0.10
Sortino ratio: Return per unit of downside risk	1.70	1.44	+0.25
Omega ratio: Gain probability vs. loss probability	1.20	1.17	+0.02
Calmar ratio: Return relative to maximum drawdown	1.56	1.23	+0.33
Martin ratio: Return relative to average drawdown	3.72	3.70	+0.03

DRUG.AX vs. F100.AX - Sharpe Ratio Comparison

The current DRUG.AX Sharpe Ratio is 1.07, which is comparable to the F100.AX Sharpe Ratio of 0.96. The chart below compares the historical Sharpe Ratios of DRUG.AX and F100.AX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

DRUG.AX vs. F100.AX - Drawdown Comparison

The maximum DRUG.AX drawdown since its inception was -26.79%, smaller than the maximum F100.AX drawdown of -31.78%. Use the drawdown chart below to compare losses from any high point for DRUG.AX and F100.AX.

Drawdown Indicators

	DRUG.AX	F100.AX	Difference
Max Drawdown Largest peak-to-trough decline	-26.79%	-31.78%	+4.99%
Max Drawdown (1Y) Largest decline over 1 year	-10.69%	-8.92%	-1.77%
Max Drawdown (3Y) Largest decline over 3 years	-20.63%	-8.92%	-11.71%
Max Drawdown (5Y) Largest decline over 5 years	-20.63%	-19.00%	-1.63%
Current Drawdown Current decline from peak	-2.61%	-1.05%	-1.56%
Average Drawdown Average peak-to-trough decline	-5.17%	-5.90%	+0.73%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.52%	3.00%	+1.52%

Volatility

DRUG.AX vs. F100.AX - Volatility Comparison

Betashares Global Healthcare Currency Hedged ETF (DRUG.AX) has a higher volatility of 6.29% compared to Betashares FTSE 100 ETF (F100.AX) at 3.07%. This indicates that DRUG.AX's price experiences larger fluctuations and is considered to be riskier than F100.AX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DRUG.AX	F100.AX	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.29%	3.07%	+3.22%
Volatility (6M) Calculated over the trailing 6-month period	11.71%	9.63%	+2.08%
Volatility (1Y) Calculated over the trailing 1-year period	15.65%	11.45%	+4.20%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.95%	12.72%	+2.23%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	16.17%	14.90%	+1.27%

DRUG.AX vs. F100.AX - Expense Ratio Comparison

DRUG.AX has a 0.57% expense ratio, which is higher than F100.AX's 0.45% expense ratio.

Dividends

DRUG.AX vs. F100.AX - Dividend Comparison

DRUG.AX's dividend yield for the trailing twelve months is around 3.63%, more than F100.AX's 2.24% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018
DRUG.AX Betashares Global Healthcare Currency Hedged ETF	3.63%	0.00%	2.84%	0.00%	0.00%	4.49%	0.62%	0.28%	3.37%
F100.AX Betashares FTSE 100 ETF	2.24%	3.09%	1.91%	1.57%	1.62%	2.13%	2.40%	0.00%	0.00%

Frequently Asked Questions

Can I hold both DRUG.AX and F100.AX in my portfolio?

DRUG.AX and F100.AX have a correlation of 0.51, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, DRUG.AX or F100.AX?

On fees, F100.AX is cheaper at 0.45% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, DRUG.AX or F100.AX?

F100.AX is cheaper with a 0.45% expense ratio, compared with 0.57% for DRUG.AX.

What is the main difference between DRUG.AX and F100.AX?

DRUG.AX is categorized as Health & Biotech Equities, while F100.AX is Global Equities. DRUG.AX tracks Nasdaq Global ex-Australia Healthcare Hedged AUD Index, while F100.AX tracks FTSE 100 Index. Their fees differ too: 0.57% for DRUG.AX and 0.45% for F100.AX.