DOCT.L vs. GNOM

Last updated Jun 5, 2026

DOCT.L (L&G Healthcare Breakthrough UCITS ETF) and GNOM (Global X Genomics & Biotechnology ETF) are both Health & Biotech Equities funds - DOCT.L tracks the MSCI World/Health Care NR USD while GNOM tracks the Solactive Genomics Index. Both are passively managed. Over the past 5 years, DOCT.L returned -3.81%/yr vs -9.59%/yr for GNOM. A 0.55 correlation means they provide meaningful diversification when combined. DOCT.L charges 0.49%/yr vs 0.50%/yr for GNOM.

Performance

DOCT.L vs. GNOM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in L&G Healthcare Breakthrough UCITS ETF (DOCT.L) and Global X Genomics & Biotechnology ETF (GNOM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, DOCT.L achieves a 0.41% return, which is significantly lower than GNOM's 11.56% return.

DOCT.L

• 1D: 5.27%
• 1M: 6.77%
• YTD: 0.41%
• 6M: 0.07%
• 1Y: 31.20%
• 3Y*: 7.08%
• 5Y*: -3.81%
• 10Y*: —

GNOM

• 1D: 3.47%
• 1M: 11.33%
• YTD: 11.56%
• 6M: 9.34%
• 1Y: 57.90%
• 3Y*: 0.45%
• 5Y*: -9.59%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

DOCT.L vs. GNOM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
DOCT.L L&G Healthcare Breakthrough UCITS ETF	0.41%	24.88%	1.98%	-1.20%	-33.86%	0.19%	66.94%	5.40%
GNOM Global X Genomics & Biotechnology ETF	11.56%	18.65%	-15.99%	-8.63%	-36.27%	-15.93%	51.52%	3.93%

Correlation

The correlation between DOCT.L and GNOM is 0.57, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.57
Correlation (3Y) Calculated over the trailing 3-year period	0.56
Correlation (5Y) Calculated over the trailing 5-year period	0.56
Correlation (All Time) Calculated using the full available price history since Jul 3, 2019	0.55

The correlation between DOCT.L and GNOM has been stable across timeframes, ranging from 0.55 to 0.57 - a consistent structural relationship.

DOCT.L vs. GNOM - Sectors Allocation Comparison

Sectors	DOCT.L	GNOM
Healthcare	98.3%	99.6%
Technology	1.7%	0.4%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-
Industrials	-	-
Real Estate	-	-
Utilities	-	-

Return for Risk

DOCT.L vs. GNOM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DOCT.L

DOCT.L Risk / Return Rank: 40
DOCT.L Sharpe Ratio Rank: 43
DOCT.L Sortino Ratio Rank: 46
DOCT.L Omega Ratio Rank: 41
DOCT.L Calmar Ratio Rank: 38
DOCT.L Martin Ratio Rank: 31

GNOM

GNOM Risk / Return Rank: 62
GNOM Sharpe Ratio Rank: 67
GNOM Sortino Ratio Rank: 68
GNOM Omega Ratio Rank: 58
GNOM Calmar Ratio Rank: 66
GNOM Martin Ratio Rank: 54

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DOCT.L vs. GNOM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for L&G Healthcare Breakthrough UCITS ETF (DOCT.L) and Global X Genomics & Biotechnology ETF (GNOM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	DOCT.L	GNOM	Difference
Sharpe ratio: Return per unit of total volatility	1.48	2.18	-0.71
Sortino ratio: Return per unit of downside risk	2.25	3.06	-0.81
Omega ratio: Gain probability vs. loss probability	1.26	1.35	-0.09
Calmar ratio: Return relative to maximum drawdown	1.82	3.20	-1.38
Martin ratio: Return relative to average drawdown	4.42	9.21	-4.79
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

DOCT.L vs. GNOM - Sharpe Ratio Comparison

The current DOCT.L Sharpe Ratio is 1.48, which is lower than the GNOM Sharpe Ratio of 2.18. The chart below compares the historical Sharpe Ratios of DOCT.L and GNOM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	DOCT.L	GNOM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.48	2.18	-0.71
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.16	-0.29	+0.13
Sharpe Ratio (All Time) Calculated using the full available price history	0.23	-0.07	+0.30

Drawdowns

DOCT.L vs. GNOM - Drawdown Comparison

The maximum DOCT.L drawdown since its inception was -57.55%, smaller than the maximum GNOM drawdown of -75.00%. Use the drawdown chart below to compare losses from any high point for DOCT.L and GNOM.

Drawdown Indicators

	DOCT.L	GNOM	Difference
Max Drawdown Largest peak-to-trough decline	-57.55%	-75.00%	+17.45%
Max Drawdown (1Y) Largest decline over 1 year	-17.02%	-18.17%	+1.15%
Max Drawdown (3Y) Largest decline over 3 years	-28.80%	-46.47%	+17.67%
Max Drawdown (5Y) Largest decline over 5 years	-55.82%	-72.29%	+16.47%
Current Drawdown Current decline from peak	-29.74%	-53.90%	+24.16%
Average Drawdown Average peak-to-trough decline	-29.05%	-40.56%	+11.51%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.04%	6.30%	+0.74%

Volatility

DOCT.L vs. GNOM - Volatility Comparison

The current volatility for L&G Healthcare Breakthrough UCITS ETF (DOCT.L) is 6.75%, while Global X Genomics & Biotechnology ETF (GNOM) has a volatility of 8.77%. This indicates that DOCT.L experiences smaller price fluctuations and is considered to be less risky than GNOM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DOCT.L	GNOM	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.75%	8.77%	-2.02%
Volatility (6M) Calculated over the trailing 6-month period	15.76%	19.72%	-3.96%
Volatility (1Y) Calculated over the trailing 1-year period	21.03%	26.66%	-5.63%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	24.01%	33.61%	-9.60%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	24.76%	34.19%	-9.43%

DOCT.L vs. GNOM - Expense Ratio Comparison

DOCT.L has a 0.49% expense ratio, which is lower than GNOM's 0.50% expense ratio.

Dividends

DOCT.L vs. GNOM - Dividend Comparison

DOCT.L has not paid dividends to shareholders, while GNOM's dividend yield for the trailing twelve months is around 1.23%.

Position	TTM	2025	2024	2023	2022	2021	2020
DOCT.L L&G Healthcare Breakthrough UCITS ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
GNOM Global X Genomics & Biotechnology ETF	1.23%	1.37%	0.00%	0.00%	0.00%	0.03%	0.14%

Frequently Asked Questions

Can I hold both DOCT.L and GNOM in my portfolio?

DOCT.L and GNOM have a correlation of 0.57, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, DOCT.L or GNOM?

On fees, DOCT.L is cheaper at 0.49% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, DOCT.L or GNOM?

DOCT.L is cheaper with a 0.49% expense ratio, compared with 0.50% for GNOM.

What is the main difference between DOCT.L and GNOM?

DOCT.L tracks MSCI World/Health Care NR USD, while GNOM tracks Solactive Genomics Index. They also come from different issuers: Legal & General and Global X. Their fees differ too: 0.49% for DOCT.L and 0.50% for GNOM.