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DCTH vs. AMLX
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

DCTH vs. AMLX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Delcath Systems, Inc. (DCTH) and Amylyx Pharmaceuticals, Inc. (AMLX). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, DCTH achieves a 20.99% return, which is significantly lower than AMLX's 68.13% return.


DCTH

1D
1.50%
1M
-7.42%
6M
23.31%
YTD
20.99%
1Y
15.39%
3Y*
42.76%
5Y*
3.68%
10Y*
ALL TIME*
-46.75%

AMLX

1D
-2.12%
1M
11.17%
6M
42.13%
YTD
68.13%
1Y
163.25%
3Y*
-4.58%
5Y*
10Y*
ALL TIME*
-0.73%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$41.59M$31.68M$25.94M
$4.25M$4.46M$5.78M

DCTH vs. AMLX - Yearly Performance Comparison


2026 (YTD)2025202420232022
DCTH
Delcath Systems, Inc.
20.99%-16.11%189.42%15.56%-51.09%
AMLX
Amylyx Pharmaceuticals, Inc.
68.13%219.58%-74.32%-60.16%75.95%

Correlation

The correlation between DCTH and AMLX is 0.37, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.37

Correlation (3Y)
Balances recent behavior with more history.

0.26

Correlation (All Time)
Calculated using the full available price history since Jan 7, 2022

0.18

The correlation between DCTH and AMLX shifts across timeframes, from 0.18 (all time) to 0.37 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

DCTH:

$421.85M

AMLX:

$2.26B

EPS

DCTH:

$0.01

AMLX:

-$1.51

PB Ratio

DCTH:

3.91

AMLX:

8.22

Total Revenue (TTM)

DCTH:

$65.45M

AMLX:

$0.00

Gross Profit (TTM)

DCTH:

$77.75M

AMLX:

-$20.10M

EBITDA (TTM)

DCTH:

$222.00K

AMLX:

-$150.30M

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Return for Risk

DCTH vs. AMLX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

DCTH
DCTH Risk / Return Rank: 5454
Overall Rank
DCTH Sharpe Ratio Rank: 5656
Sharpe Ratio Rank
DCTH Sortino Ratio Rank: 5353
Sortino Ratio Rank
DCTH Omega Ratio Rank: 5151
Omega Ratio Rank
DCTH Calmar Ratio Rank: 5656
Calmar Ratio Rank
DCTH Martin Ratio Rank: 5555
Martin Ratio Rank

AMLX
AMLX Risk / Return Rank: 9393
Overall Rank
AMLX Sharpe Ratio Rank: 9696
Sharpe Ratio Rank
AMLX Sortino Ratio Rank: 9393
Sortino Ratio Rank
AMLX Omega Ratio Rank: 8989
Omega Ratio Rank
AMLX Calmar Ratio Rank: 9595
Calmar Ratio Rank
AMLX Martin Ratio Rank: 9292
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

DCTH vs. AMLX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Delcath Systems, Inc. (DCTH) and Amylyx Pharmaceuticals, Inc. (AMLX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


DCTHAMLXDifference
Sharpe ratioReturn per unit of total volatility

-2.23

Sortino ratioReturn per unit of downside risk

-2.31

Omega ratioGain probability vs. loss probability

1.09

1.35

-0.26

Calmar ratioReturn relative to maximum drawdown

0.41

5.03

-4.62

Martin ratioReturn relative to average drawdown

0.83

10.76

-9.93

DCTH vs. AMLX - Sharpe Ratio Comparison

The current DCTH Sharpe Ratio is 0.29, which is lower than the AMLX Sharpe Ratio of 2.51. The chart below compares the historical Sharpe Ratios of DCTH and AMLX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

DCTH vs. AMLX - Drawdown Comparison

The maximum DCTH drawdown since its inception was -99.96%, roughly equal to the maximum AMLX drawdown of -96.04%. Use the drawdown chart below to compare losses from any high point for DCTH and AMLX.


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Drawdown Indicators


DCTHAMLXDifference

Max Drawdown

Largest peak-to-trough decline

-99.96%

-96.04%

-3.92%

Max Drawdown (1Y)

Largest decline over 1 year

-33.74%

-30.61%

-3.13%

Max Drawdown (3Y)

Largest decline over 3 years

-60.87%

-92.80%

+31.93%

Max Drawdown (5Y)

Largest decline over 5 years

-80.80%

Current Drawdown

Current decline from peak

-99.80%

-50.38%

-49.42%

Average Drawdown

Average peak-to-trough decline

-96.47%

-59.30%

-37.17%

Ulcer Index

Depth and duration of drawdowns from previous peaks

16.48%

14.27%

+2.21%

Volatility

DCTH vs. AMLX - Volatility Comparison

The current volatility for Delcath Systems, Inc. (DCTH) is 10.23%, while Amylyx Pharmaceuticals, Inc. (AMLX) has a volatility of 15.49%. This indicates that DCTH experiences smaller price fluctuations and is considered to be less risky than AMLX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


DCTHAMLXDifference

Volatility (1M)

Calculated over the trailing 1-month period

10.23%

15.49%

-5.26%

Volatility (6M)

Calculated over the trailing 6-month period

33.52%

39.64%

-6.12%

Volatility (1Y)

Calculated over the trailing 1-year period

48.02%

61.22%

-13.20%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

72.50%

90.71%

-18.21%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

109.21%

90.71%

+18.50%

Dividends

DCTH vs. AMLX - Dividend Comparison

Neither DCTH nor AMLX has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

DCTH vs. AMLX - Financials Comparison

This section allows you to compare key financial metrics between Delcath Systems, Inc. and Amylyx Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


DCTH and AMLX have a correlation of 0.37, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

AMLX has higher volatility (15.49%) compared to DCTH (10.23%). In terms of maximum drawdown, DCTH dropped -99.96% vs AMLX's -96.04%.

AMLX currently has the higher Sharpe Ratio (2.51 vs 0.29), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for DCTH and AMLX

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