DCTH vs. ALPMY

Last updated Apr 1, 2026

Compare and contrast key facts about Delcath Systems, Inc. (DCTH) and Astellas Pharma Inc (ALPMY).

Performance

DCTH vs. ALPMY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Delcath Systems, Inc. (DCTH) and Astellas Pharma Inc (ALPMY). The values are adjusted to include any dividend payments, if applicable.

DCTH vs. ALPMY - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
DCTH Delcath Systems, Inc.	-8.12%	-16.11%	189.42%	15.56%	-53.55%	-56.75%	-15.67%	-89.16%	-90.66%
ALPMY Astellas Pharma Inc	22.05%	41.23%	-17.10%	-21.50%	-6.82%	5.38%	-9.34%	35.81%	-18.25%

Fundamentals

Market Cap DCTH : $338.22M ALPMY : $29.15B
EPS DCTH : $0.07 ALPMY : $181.46
PE Ratio DCTH : 133.78 ALPMY : 0.09
PS Ratio DCTH : 5.60 ALPMY : 0.01
PB Ratio DCTH : 3.04 ALPMY : 0.02
Total Revenue (TTM) DCTH : $64.50M ALPMY : $2.08T
Gross Profit (TTM) DCTH : $73.43M ALPMY : $1.62T
EBITDA (TTM) DCTH : $1.61M ALPMY : $599.42B

Returns By Period

In the year-to-date period, DCTH achieves a -8.12% return, which is significantly lower than ALPMY's 22.05% return.

DCTH

• 1D: 4.39%
• 1M: 4.27%
• YTD: -8.12%
• 6M: -13.67%
• 1Y: -27.10%
• 3Y*: 17.30%
• 5Y*: -5.40%
• 10Y*: —

ALPMY

• 1D: 0.50%
• 1M: -1.76%
• YTD: 22.05%
• 6M: 49.08%
• 1Y: 67.91%
• 3Y*: 6.21%
• 5Y*: 1.96%
• 10Y*: 3.20%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

DCTH vs. ALPMY — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DCTH

DCTH Risk / Return Rank: 24
DCTH Sharpe Ratio Rank: 21
DCTH Sortino Ratio Rank: 21
DCTH Omega Ratio Rank: 23
DCTH Calmar Ratio Rank: 24
DCTH Martin Ratio Rank: 29

ALPMY

ALPMY Risk / Return Rank: 93
ALPMY Sharpe Ratio Rank: 94
ALPMY Sortino Ratio Rank: 93
ALPMY Omega Ratio Rank: 91
ALPMY Calmar Ratio Rank: 94
ALPMY Martin Ratio Rank: 93

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DCTH vs. ALPMY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Delcath Systems, Inc. (DCTH) and Astellas Pharma Inc (ALPMY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	DCTH	ALPMY	Difference
Sharpe ratio Return per unit of total volatility	-0.47	2.47	-2.94
Sortino ratio Return per unit of downside risk	-0.39	3.26	-3.65
Omega ratio Gain probability vs. loss probability	0.95	1.41	-0.45
Calmar ratio Return relative to maximum drawdown	-0.54	5.54	-6.08
Martin ratio Return relative to average drawdown	-0.77	13.50	-14.27
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

DCTH vs. ALPMY - Sharpe Ratio Comparison

The current DCTH Sharpe Ratio is -0.47, which is lower than the ALPMY Sharpe Ratio of 2.47. The chart below compares the historical Sharpe Ratios of DCTH and ALPMY, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	DCTH	ALPMY	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.47	2.47	-2.94
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.07	0.08	-0.15
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.13	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.45	-0.14	-0.31

Correlation

The correlation between DCTH and ALPMY is 0.11, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

DCTH vs. ALPMY - Dividend Comparison

Neither DCTH nor ALPMY has paid dividends to shareholders.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
DCTH Delcath Systems, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
ALPMY Astellas Pharma Inc	0.00%	1.93%	2.56%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	1.20%	2.18%

Drawdowns

DCTH vs. ALPMY - Drawdown Comparison

The maximum DCTH drawdown since its inception was -99.96%, which is greater than ALPMY's maximum drawdown of -83.67%. Use the drawdown chart below to compare losses from any high point for DCTH and ALPMY.

Drawdown Indicators

	DCTH	ALPMY	Difference
Max Drawdown Largest peak-to-trough decline	-99.96%	-83.67%	-16.29%
Max Drawdown (1Y) Largest decline over 1 year	-54.75%	-12.21%	-42.54%
Max Drawdown (5Y) Largest decline over 5 years	-85.10%	-49.11%	-35.99%
Max Drawdown (10Y) Largest decline over 10 years	—	-49.67%	—
Current Drawdown Current decline from peak	-99.85%	-70.04%	-29.81%
Average Drawdown Average peak-to-trough decline	-96.38%	-58.27%	-38.11%
Ulcer Index Depth and duration of drawdowns from previous peaks	38.26%	5.01%	+33.25%

Volatility

DCTH vs. ALPMY - Volatility Comparison

Delcath Systems, Inc. (DCTH) has a higher volatility of 12.83% compared to Astellas Pharma Inc (ALPMY) at 9.35%. This indicates that DCTH's price experiences larger fluctuations and is considered to be riskier than ALPMY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DCTH	ALPMY	Difference
Volatility (1M) Calculated over the trailing 1-month period	12.83%	9.35%	+3.48%
Volatility (6M) Calculated over the trailing 6-month period	36.46%	21.45%	+15.01%
Volatility (1Y) Calculated over the trailing 1-year period	58.48%	27.59%	+30.89%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	74.15%	25.16%	+48.99%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	111.20%	25.44%	+85.76%

Financials