DCTH vs. ALPMY

Last updated Jun 23, 2026

DCTH (Delcath Systems, Inc.) and ALPMY (Astellas Pharma Inc) are both stocks. Both are in the Healthcare sector — DCTH in Medical Devices, ALPMY in Drug Manufacturers - General. Over the past 5 years, DCTH returned 1.93%/yr vs -4.56%/yr for ALPMY. At a 0.11 correlation, their price movements are largely independent.

Performance

DCTH vs. ALPMY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Delcath Systems, Inc. (DCTH) and Astellas Pharma Inc (ALPMY). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, DCTH achieves a 13.96% return, which is significantly higher than ALPMY's 1.35% return.

DCTH

• 1D: -1.54%
• 1M: 4.45%
• YTD: 13.96%
• 6M: 14.30%
• 1Y: -16.90%
• 3Y*: 27.37%
• 5Y*: 1.93%
• 10Y*: —

ALPMY

• 1D: 0.15%
• 1M: -5.21%
• YTD: 1.35%
• 6M: 1.89%
• 1Y: 45.94%
• 3Y*: -2.47%
• 5Y*: -4.56%
• 10Y*: -0.31%

*Multi-year figures are annualized to reflect compound growth (CAGR)

DCTH vs. ALPMY - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
DCTH Delcath Systems, Inc.	13.96%	-16.11%	189.42%	15.56%	-53.55%	-56.75%	-15.67%	-89.16%	-90.69%
ALPMY Astellas Pharma Inc	1.35%	41.23%	-17.10%	-21.50%	-6.82%	5.38%	-9.34%	35.81%	-17.50%

Correlation

The correlation between DCTH and ALPMY is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.12
Correlation (3Y) Calculated over the trailing 3-year period	0.09
Correlation (5Y) Calculated over the trailing 5-year period	0.10
Correlation (All Time) Calculated using the full available price history since May 29, 2018	0.11

Fundamentals

Market Cap DCTH : $414.60M ALPMY : $24.21B
EPS DCTH : $0.01 ALPMY : ¥172.03
PE Ratio DCTH : 783.68 ALPMY : 12.65
PS Ratio DCTH : 6.72 ALPMY : 1.72
PB Ratio DCTH : 3.68 ALPMY : 2.13
Total Revenue (TTM) DCTH : $65.45M ALPMY : ¥2.27T
Gross Profit (TTM) DCTH : $77.75M ALPMY : ¥1.69T
EBITDA (TTM) DCTH : $222.00K ALPMY : ¥445.01B

Return for Risk

DCTH vs. ALPMY — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DCTH

DCTH Risk / Return Rank: 28
DCTH Sharpe Ratio Rank: 27
DCTH Sortino Ratio Rank: 27
DCTH Omega Ratio Rank: 27
DCTH Calmar Ratio Rank: 28
DCTH Martin Ratio Rank: 30

ALPMY

ALPMY Risk / Return Rank: 80
ALPMY Sharpe Ratio Rank: 84
ALPMY Sortino Ratio Rank: 81
ALPMY Omega Ratio Rank: 78
ALPMY Calmar Ratio Rank: 77
ALPMY Martin Ratio Rank: 79

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DCTH vs. ALPMY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Delcath Systems, Inc. (DCTH) and Astellas Pharma Inc (ALPMY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	DCTH	ALPMY	Difference
Sharpe ratio: Return per unit of total volatility	-0.34	1.61	-1.95
Sortino ratio: Return per unit of downside risk	-0.18	2.28	-2.46
Omega ratio: Gain probability vs. loss probability	0.98	1.28	-0.30
Calmar ratio: Return relative to maximum drawdown	-0.41	2.17	-2.58
Martin ratio: Return relative to average drawdown	-0.64	5.85	-6.49

DCTH vs. ALPMY - Sharpe Ratio Comparison

The current DCTH Sharpe Ratio is -0.34, which is lower than the ALPMY Sharpe Ratio of 1.61. The chart below compares the historical Sharpe Ratios of DCTH and ALPMY, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

DCTH vs. ALPMY - Drawdown Comparison

The maximum DCTH drawdown since its inception was -99.96%, which is greater than ALPMY's maximum drawdown of -83.67%. Use the drawdown chart below to compare losses from any high point for DCTH and ALPMY.

Drawdown Indicators

	DCTH	ALPMY	Difference
Max Drawdown Largest peak-to-trough decline	-99.96%	-83.67%	-16.29%
Max Drawdown (1Y) Largest decline over 1 year	-41.71%	-21.28%	-20.43%
Max Drawdown (3Y) Largest decline over 3 years	-62.87%	-40.38%	-22.49%
Max Drawdown (5Y) Largest decline over 5 years	-82.21%	-49.11%	-33.10%
Max Drawdown (10Y) Largest decline over 10 years	—	-49.67%	—
Current Drawdown Current decline from peak	-99.81%	-75.12%	-24.69%
Average Drawdown Average peak-to-trough decline	-96.43%	-58.44%	-37.99%
Ulcer Index Depth and duration of drawdowns from previous peaks	26.33%	7.88%	+18.45%

Volatility

DCTH vs. ALPMY - Volatility Comparison

Delcath Systems, Inc. (DCTH) has a higher volatility of 13.30% compared to Astellas Pharma Inc (ALPMY) at 9.83%. This indicates that DCTH's price experiences larger fluctuations and is considered to be riskier than ALPMY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DCTH	ALPMY	Difference
Volatility (1M) Calculated over the trailing 1-month period	13.30%	9.83%	+3.47%
Volatility (6M) Calculated over the trailing 6-month period	32.57%	22.43%	+10.14%
Volatility (1Y) Calculated over the trailing 1-year period	49.63%	28.73%	+20.90%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	73.00%	25.42%	+47.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	109.86%	25.59%	+84.27%

Dividends

DCTH vs. ALPMY - Dividend Comparison

Neither DCTH nor ALPMY has paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
ALPMY Astellas Pharma Inc	0.00%	1.93%	2.56%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	1.20%	2.18%
DCTH Delcath Systems, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both DCTH and ALPMY in my portfolio?

DCTH and ALPMY have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, DCTH or ALPMY?

DCTH has higher volatility (13.30%) compared to ALPMY (9.83%). In terms of maximum drawdown, DCTH dropped -99.96% vs ALPMY's -83.67%.

Which has better risk-adjusted returns?

ALPMY currently has the higher Sharpe Ratio (1.61 vs -0.34), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.