CTMX vs. CNTB

Last updated Jun 23, 2026

CTMX (CytomX Therapeutics, Inc.) and CNTB (Connect Biopharma Holdings Limited) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. At a 0.24 correlation, their price movements are largely independent.

Performance

CTMX vs. CNTB - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CytomX Therapeutics, Inc. (CTMX) and Connect Biopharma Holdings Limited (CNTB). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

The year-to-date returns for both stocks are quite close, with CTMX having a -28.64% return and CNTB slightly lower at -29.43%.

CTMX

• 1D: 3.05%
• 1M: -19.15%
• YTD: -28.64%
• 6M: -26.21%
• 1Y: 31.03%
• 3Y*: 25.44%
• 5Y*: -14.57%
• 10Y*: -11.07%

CNTB

• 1D: -0.50%
• 1M: -15.32%
• YTD: -29.43%
• 6M: -21.65%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CTMX vs. CNTB - Yearly Performance Comparison

	2026 (YTD)	2025
CTMX CytomX Therapeutics, Inc.	-28.64%	104.81%
CNTB Connect Biopharma Holdings Limited	-29.43%	28.18%

Correlation

The correlation between CTMX and CNTB is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (All Time) Calculated using the full available price history since Sep 3, 2025	0.24

Fundamentals

Market Cap CTMX : $538.91M CNTB : $110.76M
EPS CTMX : -$0.37 CNTB : -$1.28
PS Ratio CTMX : 13.72 CNTB : 4.25
PB Ratio CTMX : 1.68 CNTB : 2.64
Total Revenue (TTM) CTMX : $35.54M CNTB : $26.03M
Gross Profit (TTM) CTMX : $24.77M CNTB : $25.37M
EBITDA (TTM) CTMX : -$62.07M CNTB : -$72.75M

Return for Risk

CTMX vs. CNTB — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CTMX

CTMX Risk / Return Rank: 57
CTMX Sharpe Ratio Rank: 54
CTMX Sortino Ratio Rank: 61
CTMX Omega Ratio Rank: 60
CTMX Calmar Ratio Rank: 55
CTMX Martin Ratio Rank: 57

CNTB

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CTMX vs. CNTB - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for CytomX Therapeutics, Inc. (CTMX) and Connect Biopharma Holdings Limited (CNTB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	CTMX	CNTB	Difference
Sharpe ratio: Return per unit of total volatility	0.33	—	—
Sortino ratio: Return per unit of downside risk	1.25	—	—
Omega ratio: Gain probability vs. loss probability	1.16	—	—
Calmar ratio: Return relative to maximum drawdown	0.55	—	—
Martin ratio: Return relative to average drawdown	1.29	—	—

Drawdowns

CTMX vs. CNTB - Drawdown Comparison

The maximum CTMX drawdown since its inception was -98.74%, which is greater than CNTB's maximum drawdown of -46.07%. Use the drawdown chart below to compare losses from any high point for CTMX and CNTB.

Drawdown Indicators

	CTMX	CNTB	Difference
Max Drawdown Largest peak-to-trough decline	-98.74%	-46.07%	-52.67%
Max Drawdown (1Y) Largest decline over 1 year	-56.89%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-91.59%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-94.16%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-98.74%	—	—
Current Drawdown Current decline from peak	-91.12%	-46.07%	-45.05%
Average Drawdown Average peak-to-trough decline	-70.93%	-23.71%	-47.22%
Ulcer Index Depth and duration of drawdowns from previous peaks	24.04%	—	—

Volatility

Volatility by Period

	CTMX	CNTB	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.08%	—	—
Volatility (6M) Calculated over the trailing 6-month period	67.28%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	93.83%	93.92%	-0.09%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	141.88%	93.92%	+47.96%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	111.37%	93.92%	+17.45%

Dividends

CTMX vs. CNTB - Dividend Comparison

Neither CTMX nor CNTB has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CTMX and CNTB in my portfolio?

CTMX and CNTB have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.