CRSP vs. QCOM

Last updated Jun 13, 2026

CRSP (CRISPR Therapeutics AG) and QCOM (QUALCOMM Incorporated) are both stocks. CRSP operates in Biotechnology (Healthcare), while QCOM operates in Semiconductors (Technology). Over the past 5 years, CRSP returned -17.08%/yr vs 11.87%/yr for QCOM. At a 0.34 correlation, their price movements are largely independent.

Performance

CRSP vs. QCOM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CRISPR Therapeutics AG (CRSP) and QUALCOMM Incorporated (QCOM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CRSP achieves a -5.03% return, which is significantly lower than QCOM's 25.03% return.

CRSP

• 1D: -0.86%
• 1M: 2.87%
• YTD: -5.03%
• 6M: -12.14%
• 1Y: 20.41%
• 3Y*: -6.43%
• 5Y*: -17.08%
• 10Y*: —

QCOM

• 1D: 4.32%
• 1M: 5.47%
• YTD: 25.03%
• 6M: 19.95%
• 1Y: 39.72%
• 3Y*: 22.00%
• 5Y*: 11.87%
• 10Y*: 18.10%

*Multi-year figures are annualized to reflect compound growth (CAGR)

CRSP vs. QCOM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CRSP CRISPR Therapeutics AG	-5.03%	33.23%	-37.12%	54.00%	-46.36%	-50.51%	151.39%	113.18%	21.68%	15.89%
QCOM QUALCOMM Incorporated	25.03%	13.84%	8.31%	35.07%	-38.58%	22.25%	77.08%	60.76%	-7.59%	2.05%

Correlation

The correlation between CRSP and QCOM is 0.32, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.32
Correlation (3Y) Calculated over the trailing 3-year period	0.38
Correlation (5Y) Calculated over the trailing 5-year period	0.39
Correlation (All Time) Calculated using the full available price history since Oct 19, 2016	0.34

Fundamentals

Market Cap CRSP : $4.78B QCOM : $226.96B
EPS CRSP : -$6.24 QCOM : $9.11
PS Ratio CRSP : 1.11K QCOM : 5.18
PB Ratio CRSP : 2.64 QCOM : 8.32
Total Revenue (TTM) CRSP : $4.10M QCOM : $44.49B
Gross Profit (TTM) CRSP : -$171.17M QCOM : $24.38B
EBITDA (TTM) CRSP : -$509.21M QCOM : $12.92B

Return for Risk

CRSP vs. QCOM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CRSP

CRSP Risk / Return Rank: 54
CRSP Sharpe Ratio Rank: 55
CRSP Sortino Ratio Rank: 55
CRSP Omega Ratio Rank: 52
CRSP Calmar Ratio Rank: 54
CRSP Martin Ratio Rank: 53

QCOM

QCOM Risk / Return Rank: 66
QCOM Sharpe Ratio Rank: 68
QCOM Sortino Ratio Rank: 65
QCOM Omega Ratio Rank: 67
QCOM Calmar Ratio Rank: 65
QCOM Martin Ratio Rank: 65

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CRSP vs. QCOM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for CRISPR Therapeutics AG (CRSP) and QUALCOMM Incorporated (QCOM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	CRSP	QCOM	Difference
Sharpe ratio: Return per unit of total volatility	0.33	0.75	-0.42
Sortino ratio: Return per unit of downside risk	0.94	1.36	-0.41
Omega ratio: Gain probability vs. loss probability	1.11	1.19	-0.08
Calmar ratio: Return relative to maximum drawdown	0.49	1.10	-0.61
Martin ratio: Return relative to average drawdown	0.81	2.44	-1.63

CRSP vs. QCOM - Sharpe Ratio Comparison

The current CRSP Sharpe Ratio is 0.33, which is lower than the QCOM Sharpe Ratio of 0.75. The chart below compares the historical Sharpe Ratios of CRSP and QCOM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

CRSP vs. QCOM - Drawdown Comparison

The maximum CRSP drawdown since its inception was -85.11%, roughly equal to the maximum QCOM drawdown of -86.75%. Use the drawdown chart below to compare losses from any high point for CRSP and QCOM.

Drawdown Indicators

	CRSP	QCOM	Difference
Max Drawdown Largest peak-to-trough decline	-85.11%	-86.75%	+1.64%
Max Drawdown (1Y) Largest decline over 1 year	-42.25%	-33.13%	-9.12%
Max Drawdown (3Y) Largest decline over 3 years	-64.91%	-44.23%	-20.68%
Max Drawdown (5Y) Largest decline over 5 years	-80.68%	-44.29%	-36.39%
Max Drawdown (10Y) Largest decline over 10 years	—	-44.29%	—
Current Drawdown Current decline from peak	-76.29%	-15.34%	-60.95%
Average Drawdown Average peak-to-trough decline	-49.24%	-32.87%	-16.37%
Ulcer Index Depth and duration of drawdowns from previous peaks	25.51%	14.89%	+10.62%

Volatility

CRSP vs. QCOM - Volatility Comparison

The current volatility for CRISPR Therapeutics AG (CRSP) is 18.22%, while QUALCOMM Incorporated (QCOM) has a volatility of 27.32%. This indicates that CRSP experiences smaller price fluctuations and is considered to be less risky than QCOM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CRSP	QCOM	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.22%	27.32%	-9.10%
Volatility (6M) Calculated over the trailing 6-month period	43.62%	42.18%	+1.44%
Volatility (1Y) Calculated over the trailing 1-year period	62.44%	48.52%	+13.92%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	60.65%	41.17%	+19.48%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	64.35%	39.28%	+25.07%

Dividends

CRSP vs. QCOM - Dividend Comparison

CRSP has not paid dividends to shareholders, while QCOM's dividend yield for the trailing twelve months is around 1.70%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CRSP CRISPR Therapeutics AG	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
QCOM QUALCOMM Incorporated	1.70%	2.06%	2.18%	2.18%	2.67%	1.47%	1.69%	2.81%	4.27%	3.50%	3.17%	3.72%

Financials

Frequently Asked Questions

Can I hold both CRSP and QCOM in my portfolio?

CRSP and QCOM have a correlation of 0.32, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CRSP or QCOM?

QCOM has higher volatility (27.32%) compared to CRSP (18.22%). In terms of maximum drawdown, CRSP dropped -85.11% vs QCOM's -86.75%.

Which has better risk-adjusted returns?

QCOM currently has the higher Sharpe Ratio (0.75 vs 0.33), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.