CMNIX vs. ETHSX

Last updated Jun 13, 2026

CMNIX (Calamos Market Neutral Income Fund Institutional Class) and ETHSX (Eaton Vance Worldwide Health Sciences Fund) are both mutual funds - CMNIX is a fund fund managed by Calamos, while ETHSX is a Health & Biotech Equities fund managed by Eaton Vance. Over the past 10 years, CMNIX returned 4.79%/yr vs 7.46%/yr for ETHSX. A 0.55 correlation means they provide meaningful diversification when combined. CMNIX charges 0.90%/yr vs 1.20%/yr for ETHSX.

Performance

CMNIX vs. ETHSX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Calamos Market Neutral Income Fund Institutional Class (CMNIX) and Eaton Vance Worldwide Health Sciences Fund (ETHSX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CMNIX achieves a 2.67% return, which is significantly higher than ETHSX's -4.74% return. Over the past 10 years, CMNIX has underperformed ETHSX with an annualized return of 4.79%, while ETHSX has yielded a comparatively higher 7.46% annualized return.

CMNIX

• 1D: 0.00%
• 1M: 0.06%
• YTD: 2.67%
• 6M: 2.93%
• 1Y: 6.67%
• 3Y*: 6.99%
• 5Y*: 4.77%
• 10Y*: 4.79%

ETHSX

• 1D: 1.28%
• 1M: 3.43%
• YTD: -4.74%
• 6M: -3.58%
• 1Y: 4.68%
• 3Y*: 4.06%
• 5Y*: 3.18%
• 10Y*: 7.46%

*Multi-year figures are annualized to reflect compound growth (CAGR)

CMNIX vs. ETHSX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CMNIX Calamos Market Neutral Income Fund Institutional Class	2.67%	6.89%	7.43%	9.17%	-4.26%	5.02%	5.36%	6.72%	1.79%	4.21%
ETHSX Eaton Vance Worldwide Health Sciences Fund	-4.74%	10.23%	3.48%	5.67%	-9.41%	22.02%	13.04%	25.99%	5.87%	16.24%

Correlation

The correlation between CMNIX and ETHSX is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.16
Correlation (3Y) Calculated over the trailing 3-year period	0.37
Correlation (5Y) Calculated over the trailing 5-year period	0.53
Correlation (10Y) Calculated over the trailing 10-year period	0.55
Correlation (All Time) Calculated using the full available price history since May 10, 2000	0.55

Over the past year, the correlation between CMNIX and ETHSX has dropped to 0.16 - well below their long-term average of 0.55, suggesting their price drivers have been diverging.

Return for Risk

CMNIX vs. ETHSX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CMNIX

CMNIX Risk / Return Rank: 98
CMNIX Sharpe Ratio Rank: 98
CMNIX Sortino Ratio Rank: 98
CMNIX Omega Ratio Rank: 97
CMNIX Calmar Ratio Rank: 97
CMNIX Martin Ratio Rank: 99

ETHSX

ETHSX Risk / Return Rank: 6
ETHSX Sharpe Ratio Rank: 6
ETHSX Sortino Ratio Rank: 6
ETHSX Omega Ratio Rank: 6
ETHSX Calmar Ratio Rank: 6
ETHSX Martin Ratio Rank: 5

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CMNIX vs. ETHSX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Calamos Market Neutral Income Fund Institutional Class (CMNIX) and Eaton Vance Worldwide Health Sciences Fund (ETHSX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	CMNIX	ETHSX	Difference
Sharpe ratio: Return per unit of total volatility	3.60	0.26	+3.33
Sortino ratio: Return per unit of downside risk	5.79	0.51	+5.29
Omega ratio: Gain probability vs. loss probability	1.92	1.06	+0.86
Calmar ratio: Return relative to maximum drawdown	6.45	0.33	+6.12
Martin ratio: Return relative to average drawdown	39.12	0.77	+38.35

CMNIX vs. ETHSX - Sharpe Ratio Comparison

The current CMNIX Sharpe Ratio is 3.60, which is higher than the ETHSX Sharpe Ratio of 0.26. The chart below compares the historical Sharpe Ratios of CMNIX and ETHSX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

CMNIX vs. ETHSX - Drawdown Comparison

The maximum CMNIX drawdown since its inception was -35.16%, smaller than the maximum ETHSX drawdown of -90.06%. Use the drawdown chart below to compare losses from any high point for CMNIX and ETHSX.

Drawdown Indicators

	CMNIX	ETHSX	Difference
Max Drawdown Largest peak-to-trough decline	-35.16%	-90.06%	+54.90%
Max Drawdown (1Y) Largest decline over 1 year	-1.02%	-12.35%	+11.33%
Max Drawdown (3Y) Largest decline over 3 years	-2.77%	-18.91%	+16.14%
Max Drawdown (5Y) Largest decline over 5 years	-7.52%	-19.58%	+12.06%
Max Drawdown (10Y) Largest decline over 10 years	-8.12%	-27.43%	+19.31%
Current Drawdown Current decline from peak	-0.25%	-9.31%	+9.06%
Average Drawdown Average peak-to-trough decline	-7.15%	-43.95%	+36.80%
Ulcer Index Depth and duration of drawdowns from previous peaks	0.17%	5.27%	-5.10%

Volatility

CMNIX vs. ETHSX - Volatility Comparison

The current volatility for Calamos Market Neutral Income Fund Institutional Class (CMNIX) is 0.32%, while Eaton Vance Worldwide Health Sciences Fund (ETHSX) has a volatility of 5.26%. This indicates that CMNIX experiences smaller price fluctuations and is considered to be less risky than ETHSX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CMNIX	ETHSX	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.32%	5.26%	-4.94%
Volatility (6M) Calculated over the trailing 6-month period	1.53%	10.98%	-9.45%
Volatility (1Y) Calculated over the trailing 1-year period	1.82%	15.40%	-13.58%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	3.47%	14.98%	-11.51%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	3.62%	16.27%	-12.65%

CMNIX vs. ETHSX - Expense Ratio Comparison

CMNIX has a 0.90% expense ratio, which is lower than ETHSX's 1.20% expense ratio.

Dividends

CMNIX vs. ETHSX - Dividend Comparison

CMNIX's dividend yield for the trailing twelve months is around 1.71%, less than ETHSX's 7.73% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CMNIX Calamos Market Neutral Income Fund Institutional Class	1.71%	1.63%	2.00%	5.90%	1.02%	0.46%	0.90%	1.57%	5.02%	2.60%	2.97%	2.42%
ETHSX Eaton Vance Worldwide Health Sciences Fund	7.73%	7.36%	4.81%	2.48%	4.43%	8.25%	7.33%	5.39%	5.51%	2.82%	12.75%	9.70%

Frequently Asked Questions

Can I hold both CMNIX and ETHSX in my portfolio?

CMNIX and ETHSX have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CMNIX or ETHSX?

ETHSX has higher volatility (5.26%) compared to CMNIX (0.32%). In terms of maximum drawdown, CMNIX dropped -35.16% vs ETHSX's -90.06%.

Which has better risk-adjusted returns?

CMNIX currently has the higher Sharpe Ratio (3.60 vs 0.26), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.