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ETHSX vs. AGEN
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between ETHSX and AGEN is 0.36, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.00.4

Performance

ETHSX vs. AGEN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Eaton Vance Worldwide Health Sciences Fund (ETHSX) and Agenus Inc. (AGEN). The values are adjusted to include any dividend payments, if applicable.

-80.00%-60.00%-40.00%-20.00%0.00%AugustSeptemberOctoberNovemberDecember2025
-7.49%
-83.33%
ETHSX
AGEN

Key characteristics

Sharpe Ratio

ETHSX:

0.17

AGEN:

-0.62

Sortino Ratio

ETHSX:

0.31

AGEN:

-0.64

Omega Ratio

ETHSX:

1.04

AGEN:

0.91

Calmar Ratio

ETHSX:

0.14

AGEN:

-0.78

Martin Ratio

ETHSX:

0.36

AGEN:

-1.34

Ulcer Index

ETHSX:

5.18%

AGEN:

58.19%

Daily Std Dev

ETHSX:

11.22%

AGEN:

125.30%

Max Drawdown

ETHSX:

-45.11%

AGEN:

-99.96%

Current Drawdown

ETHSX:

-12.63%

AGEN:

-99.96%

Returns By Period

In the year-to-date period, ETHSX achieves a 1.16% return, which is significantly lower than AGEN's 14.78% return. Over the past 10 years, ETHSX has outperformed AGEN with an annualized return of 3.73%, while AGEN has yielded a comparatively lower -30.00% annualized return.


ETHSX

YTD

1.16%

1M

-1.87%

6M

-7.49%

1Y

1.95%

5Y*

6.19%

10Y*

3.73%

AGEN

YTD

14.78%

1M

3.11%

6M

-82.23%

1Y

-75.43%

5Y*

-47.18%

10Y*

-30.00%

*Annualized

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Risk-Adjusted Performance

ETHSX vs. AGEN — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ETHSX
The Risk-Adjusted Performance Rank of ETHSX is 2121
Overall Rank
The Sharpe Ratio Rank of ETHSX is 2121
Sharpe Ratio Rank
The Sortino Ratio Rank of ETHSX is 2222
Sortino Ratio Rank
The Omega Ratio Rank of ETHSX is 2020
Omega Ratio Rank
The Calmar Ratio Rank of ETHSX is 2525
Calmar Ratio Rank
The Martin Ratio Rank of ETHSX is 1818
Martin Ratio Rank

AGEN
The Risk-Adjusted Performance Rank of AGEN is 1414
Overall Rank
The Sharpe Ratio Rank of AGEN is 1717
Sharpe Ratio Rank
The Sortino Ratio Rank of AGEN is 1919
Sortino Ratio Rank
The Omega Ratio Rank of AGEN is 1818
Omega Ratio Rank
The Calmar Ratio Rank of AGEN is 66
Calmar Ratio Rank
The Martin Ratio Rank of AGEN is 1212
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

ETHSX vs. AGEN - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Eaton Vance Worldwide Health Sciences Fund (ETHSX) and Agenus Inc. (AGEN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for ETHSX, currently valued at 0.17, compared to the broader market-1.000.001.002.003.004.000.17-0.62
The chart of Sortino ratio for ETHSX, currently valued at 0.31, compared to the broader market0.002.004.006.008.0010.000.31-0.64
The chart of Omega ratio for ETHSX, currently valued at 1.04, compared to the broader market1.002.003.001.040.91
The chart of Calmar ratio for ETHSX, currently valued at 0.14, compared to the broader market0.005.0010.0015.000.14-0.78
The chart of Martin ratio for ETHSX, currently valued at 0.36, compared to the broader market0.0020.0040.0060.000.36-1.34
ETHSX
AGEN

The current ETHSX Sharpe Ratio is 0.17, which is higher than the AGEN Sharpe Ratio of -0.62. The chart below compares the historical Sharpe Ratios of ETHSX and AGEN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00AugustSeptemberOctoberNovemberDecember2025
0.17
-0.62
ETHSX
AGEN

Dividends

ETHSX vs. AGEN - Dividend Comparison

ETHSX's dividend yield for the trailing twelve months is around 0.18%, while AGEN has not paid dividends to shareholders.


TTM2024202320222021202020192018
ETHSX
Eaton Vance Worldwide Health Sciences Fund
0.18%0.19%0.13%0.21%0.24%0.51%0.58%0.34%
AGEN
Agenus Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Drawdowns

ETHSX vs. AGEN - Drawdown Comparison

The maximum ETHSX drawdown since its inception was -45.11%, smaller than the maximum AGEN drawdown of -99.96%. Use the drawdown chart below to compare losses from any high point for ETHSX and AGEN. For additional features, visit the drawdowns tool.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%AugustSeptemberOctoberNovemberDecember2025
-12.63%
-99.96%
ETHSX
AGEN

Volatility

ETHSX vs. AGEN - Volatility Comparison

The current volatility for Eaton Vance Worldwide Health Sciences Fund (ETHSX) is 3.42%, while Agenus Inc. (AGEN) has a volatility of 24.03%. This indicates that ETHSX experiences smaller price fluctuations and is considered to be less risky than AGEN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%20.00%40.00%60.00%80.00%100.00%AugustSeptemberOctoberNovemberDecember2025
3.42%
24.03%
ETHSX
AGEN
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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