CLSD vs. ATYR
CLSD (Clearside Biomedical, Inc.) and ATYR (aTyr Pharma, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, CLSD returned -42.62%/yr vs -36.72%/yr for ATYR. At a 0.18 correlation, their price movements are largely independent.
Performance
CLSD vs. ATYR - Performance Comparison
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Returns By Period
Over the past 10 years, CLSD has underperformed ATYR with an annualized return of -42.62%, while ATYR has yielded a comparatively higher -36.72% annualized return.
CLSD
- 1D
- 0.00%
- 1M
- 0.00%
- YTD
- 0.00%
- 6M
- 0.00%
- 1Y
- -96.28%
- 3Y*
- -71.25%
- 5Y*
- -60.63%
- 10Y*
- -42.62%
ATYR
- 1D
- -3.83%
- 1M
- -40.67%
- YTD
- -36.14%
- 6M
- -35.12%
- 1Y
- -90.72%
- 3Y*
- -40.04%
- 5Y*
- -35.73%
- 10Y*
- -36.72%
CLSD vs. ATYR - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
CLSD Clearside Biomedical, Inc. | 0.00% | -97.12% | -18.80% | 4.46% | -59.27% | 0.36% | -5.52% | 171.03% | -84.71% | -21.70% |
ATYR aTyr Pharma, Inc. | -36.14% | -78.37% | 156.74% | -35.62% | -70.68% | 92.53% | -6.95% | -39.91% | -85.84% | 62.79% |
Correlation
The correlation between CLSD and ATYR is 0.08, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.08 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.15 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.22 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.18 |
Correlation (All Time) Calculated using the full available price history since Jun 3, 2016 | 0.18 |
The correlation between CLSD and ATYR shifts across timeframes, from 0.08 (1 year) to 0.22 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
CLSD:
$2.15M
ATYR:
$49.03M
CLSD:
-$4.99
ATYR:
-$0.73
CLSD:
0.64
ATYR:
252.24
CLSD:
$3.33M
ATYR:
$190.00K
CLSD:
$2.85M
ATYR:
-$22.33M
CLSD:
-$14.37M
ATYR:
-$71.35M
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Return for Risk
CLSD vs. ATYR — Risk / Return Rank
CLSD
ATYR
CLSD vs. ATYR - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Clearside Biomedical, Inc. (CLSD) and aTyr Pharma, Inc. (ATYR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| CLSD | ATYR | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.04 | ||
| Sortino ratioReturn per unit of downside risk | -1.76 | ||
| Omega ratioGain probability vs. loss probability | 0.54 | 0.88 | -0.34 |
| Calmar ratioReturn relative to maximum drawdown | -1.01 | -0.97 | -0.05 |
| Martin ratioReturn relative to average drawdown | -1.31 | -1.21 | -0.10 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| CLSD | ATYR | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.69 | -0.65 | -0.04 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.66 | -0.40 | -0.26 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.46 | -0.42 | -0.05 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.46 | -0.47 | +0.01 |
Drawdowns
CLSD vs. ATYR - Drawdown Comparison
The maximum CLSD drawdown since its inception was -99.89%, roughly equal to the maximum ATYR drawdown of -99.90%. Use the drawdown chart below to compare losses from any high point for CLSD and ATYR.
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Drawdown Indicators
| CLSD | ATYR | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.89% | -99.90% | +0.01% |
Max Drawdown (1Y)Largest decline over 1 year | -96.91% | -94.01% | -2.90% |
Max Drawdown (3Y)Largest decline over 3 years | -98.65% | -94.01% | -4.64% |
Max Drawdown (5Y)Largest decline over 5 years | -99.62% | -96.83% | -2.79% |
Max Drawdown (10Y)Largest decline over 10 years | -99.89% | -99.55% | -0.34% |
Current DrawdownCurrent decline from peak | -99.89% | -99.87% | -0.02% |
Average DrawdownAverage peak-to-trough decline | -83.74% | -93.18% | +9.44% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 70.11% | 74.79% | -4.68% |
Volatility
CLSD vs. ATYR - Volatility Comparison
The current volatility for Clearside Biomedical, Inc. (CLSD) is 0.00%, while aTyr Pharma, Inc. (ATYR) has a volatility of 82.02%. This indicates that CLSD experiences smaller price fluctuations and is considered to be less risky than ATYR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| CLSD | ATYR | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 0.00% | 82.02% | -82.02% |
Volatility (6M)Calculated over the trailing 6-month period | 126.86% | 95.15% | +31.71% |
Volatility (1Y)Calculated over the trailing 1-year period | 141.62% | 140.03% | +1.59% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 93.89% | 89.65% | +4.24% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 93.71% | 88.34% | +5.37% |
Dividends
CLSD vs. ATYR - Dividend Comparison
Neither CLSD nor ATYR has paid dividends to shareholders.
Financials
CLSD vs. ATYR - Financials Comparison
This section allows you to compare key financial metrics between Clearside Biomedical, Inc. and aTyr Pharma, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
CLSD and ATYR have a correlation of 0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ATYR has higher volatility (82.02%) compared to CLSD (0.00%). In terms of maximum drawdown, CLSD dropped -99.89% vs ATYR's -99.90%.
ATYR currently has the higher Sharpe Ratio (-0.65 vs -0.69), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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