Highlights
- EPS (TTM)
- -$0.80
- Total Revenue (TTM)
- $190.00K
- Gross Profit (TTM)
- -$34.17M
- EBITDA (TTM)
- -$76.54M
- Year Range
- $0.64 - $7.29
- Target Price
- $1.17
- ROA (TTM)
- -80.77%
- ROE (TTM)
- -111.32%
Share Price Chart
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Performance
Performance Chart
The chart shows the growth of an initial investment of $10,000 in aTyr Pharma, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.
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Returns By Period
aTyr Pharma, Inc. (ATYR) has returned -0.40% so far this year and -74.17% over the past 12 months. Over the last ten years, ATYR has returned -34.46% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.
aTyr Pharma, Inc.
- 1D
- 6.72%
- 1M
- -18.73%
- YTD
- -0.40%
- 6M
- 8.12%
- 1Y
- -74.17%
- 3Y*
- -28.12%
- 5Y*
- -29.78%
- 10Y*
- -34.46%
Benchmark (S&P 500 Index)
- 1D
- 2.91%
- 1M
- -5.09%
- YTD
- -4.63%
- 6M
- -2.39%
- 1Y
- 16.33%
- 3Y*
- 16.69%
- 5Y*
- 10.18%
- 10Y*
- 12.16%
Monthly Returns
Based on dividend-adjusted daily data since May 7, 2015, ATYR's average daily return is -0.04%, while the average monthly return is -1.28%.
Historically, 45% of months were positive and 55% were negative. The best month was Oct 2024 with a return of +77.3%, while the worst month was Sep 2025 at -86.6%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 6 months.
On a daily basis, ATYR closed higher 44% of trading days. The best single day was Sep 13, 2021 with a return of +67.0%, while the worst single day was Sep 15, 2025 at -83.2%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 12.73% | 8.72% | -18.73% | -0.40% | |||||||||
| 2025 | 6.63% | 2.46% | -23.64% | 14.90% | 28.82% | 13.42% | -6.90% | 13.98% | -86.59% | 20.04% | -9.87% | 0.33% | -78.37% |
| 2024 | 13.12% | 20.38% | 1.56% | -19.49% | 10.19% | -9.83% | 26.92% | -5.56% | -5.88% | 77.27% | 13.14% | 2.55% | 156.74% |
| 2023 | 5.02% | -8.26% | -0.47% | -7.14% | 16.41% | -4.85% | -9.26% | -13.27% | -7.06% | -20.89% | 4.00% | 8.46% | -35.62% |
| 2022 | -23.83% | -12.83% | 7.86% | -22.24% | -32.45% | 0.71% | 24.03% | -2.56% | -12.28% | -17.67% | -12.55% | 1.39% | -70.68% |
| 2021 | -5.41% | 18.53% | 2.30% | -8.99% | 12.10% | 7.49% | -4.51% | 18.35% | 64.64% | -5.40% | -2.91% | -10.43% | 92.53% |
Benchmark Metrics
aTyr Pharma, Inc. has an annualized alpha of -19.19%, beta of 0.98, and R² of 0.04 versus S&P 500 Index. Calculated based on daily prices since May 08, 2015.
- This stock participated in 190.60% of S&P 500 Index downside but only -29.68% of its upside — more exposed to losses than it benefited from rallies.
- R² of 0.04 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -19.19%
- Beta
- 0.98
- R²
- 0.04
- Upside Capture
- -29.68%
- Downside Capture
- 190.60%
Return for Risk
Risk / Return Rank
ATYR ranks 20 for risk / return — in the bottom 20% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for aTyr Pharma, Inc. (ATYR) and compare them to a chosen benchmark (S&P 500 Index).
| ATYR | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.61 | 0.90 | -1.51 |
Sortino ratioReturn per unit of downside risk | -0.03 | 1.39 | -1.41 |
Omega ratioGain probability vs. loss probability | 1.00 | 1.21 | -0.22 |
Calmar ratioReturn relative to maximum drawdown | -0.83 | 1.40 | -2.23 |
Martin ratioReturn relative to average drawdown | -1.16 | 6.61 | -7.76 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Explore ATYR risk-adjusted metrics in detail
Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the aTyr Pharma, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the aTyr Pharma, Inc. was 99.83%, occurring on Nov 20, 2025. The portfolio has not yet recovered.
The current aTyr Pharma, Inc. drawdown is 99.80%.
Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -99.83% | Jun 4, 2015 | 2634 | Nov 20, 2025 | — | — | — |
| -9.67% | May 27, 2015 | 3 | May 29, 2015 | 3 | Jun 3, 2015 | 6 |
| -9.18% | May 13, 2015 | 1 | May 13, 2015 | 5 | May 20, 2015 | 6 |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of aTyr Pharma, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how aTyr Pharma, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for ATYR relative to other companies in the Biotechnology industry. Currently, ATYR has a P/S ratio of 384.4. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.
Income Statement
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EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
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Other Non-Operating Income (Expenses) | — |
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Discontinued Operations | — |
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Non Recurring | — |
Minority Interest | — |
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Net Interest Income | — |