CADL vs. JANX

Last updated Jun 4, 2026

CADL (Candel Therapeutics, Inc.) and JANX (Janux Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, CADL returned 79.17%/yr vs -0.20%/yr for JANX. At a 0.19 correlation, their price movements are largely independent.

Performance

CADL vs. JANX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Candel Therapeutics, Inc. (CADL) and Janux Therapeutics, Inc. (JANX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CADL achieves a 55.75% return, which is significantly higher than JANX's -1.52% return.

CADL

• 1D: 4.51%
• 1M: 16.87%
• YTD: 55.75%
• 6M: 75.30%
• 1Y: 53.04%
• 3Y*: 79.17%
• 5Y*: —
• 10Y*: —

JANX

• 1D: -1.38%
• 1M: -5.76%
• YTD: -1.52%
• 6M: -20.57%
• 1Y: -46.56%
• 3Y*: -0.20%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CADL vs. JANX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
CADL Candel Therapeutics, Inc.	55.75%	-34.91%	490.48%	-17.88%	-77.11%	11.71%
JANX Janux Therapeutics, Inc.	-1.52%	-74.22%	398.97%	-18.53%	-33.25%	-28.51%

Correlation

The correlation between CADL and JANX is 0.40, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.40
Correlation (3Y) Calculated over the trailing 3-year period	0.21
Correlation (All Time) Calculated using the full available price history since Jul 28, 2021	0.19

Over the past year, CADL and JANX have become more correlated (0.40) than their long-term average of 0.19, meaning their price movements have been converging.

Fundamentals

Market Cap CADL : $548.78M JANX : $851.63M
EPS CADL : -$0.97 JANX : -$1.84
PB Ratio CADL : 3.98 JANX : 0.90
Total Revenue (TTM) CADL : $0.00 JANX : $21.61M
Gross Profit (TTM) CADL : -$600.00K JANX : $8.44M
EBITDA (TTM) CADL : -$71.64M JANX : -$134.03M

Return for Risk

CADL vs. JANX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CADL

CADL Risk / Return Rank: 65
CADL Sharpe Ratio Rank: 64
CADL Sortino Ratio Rank: 66
CADL Omega Ratio Rank: 63
CADL Calmar Ratio Rank: 68
CADL Martin Ratio Rank: 63

JANX

JANX Risk / Return Rank: 17
JANX Sharpe Ratio Rank: 14
JANX Sortino Ratio Rank: 20
JANX Omega Ratio Rank: 17
JANX Calmar Ratio Rank: 14
JANX Martin Ratio Rank: 17

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CADL vs. JANX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Candel Therapeutics, Inc. (CADL) and Janux Therapeutics, Inc. (JANX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CADL	JANX	Difference
Sharpe ratio: Return per unit of total volatility	0.73	-0.63	+1.36
Sortino ratio: Return per unit of downside risk	1.55	-0.43	+1.98
Omega ratio: Gain probability vs. loss probability	1.18	0.92	+0.26
Calmar ratio: Return relative to maximum drawdown	1.44	-0.72	+2.16
Martin ratio: Return relative to average drawdown	2.54	-1.10	+3.63
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CADL vs. JANX - Sharpe Ratio Comparison

The current CADL Sharpe Ratio is 0.73, which is higher than the JANX Sharpe Ratio of -0.63. The chart below compares the historical Sharpe Ratios of CADL and JANX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	CADL	JANX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.73	-0.63	+1.36
Sharpe Ratio (All Time) Calculated using the full available price history	0.03	-0.09	+0.12

Drawdowns

CADL vs. JANX - Drawdown Comparison

The maximum CADL drawdown since its inception was -94.33%, which is greater than JANX's maximum drawdown of -83.14%. Use the drawdown chart below to compare losses from any high point for CADL and JANX.

Drawdown Indicators

	CADL	JANX	Difference
Max Drawdown Largest peak-to-trough decline	-94.33%	-83.14%	-11.19%
Max Drawdown (1Y) Largest decline over 1 year	-37.04%	-64.94%	+27.90%
Max Drawdown (3Y) Largest decline over 3 years	-72.86%	-81.78%	+8.92%
Current Drawdown Current decline from peak	-37.14%	-79.67%	+42.53%
Average Drawdown Average peak-to-trough decline	-62.79%	-52.01%	-10.78%
Ulcer Index Depth and duration of drawdowns from previous peaks	20.98%	42.42%	-21.44%

Volatility

CADL vs. JANX - Volatility Comparison

Candel Therapeutics, Inc. (CADL) has a higher volatility of 16.28% compared to Janux Therapeutics, Inc. (JANX) at 9.11%. This indicates that CADL's price experiences larger fluctuations and is considered to be riskier than JANX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CADL	JANX	Difference
Volatility (1M) Calculated over the trailing 1-month period	16.28%	9.11%	+7.17%
Volatility (6M) Calculated over the trailing 6-month period	53.92%	82.02%	-28.10%
Volatility (1Y) Calculated over the trailing 1-year period	72.87%	74.22%	-1.35%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	167.21%	131.36%	+35.85%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	167.21%	131.36%	+35.85%

Dividends

CADL vs. JANX - Dividend Comparison

Neither CADL nor JANX has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CADL and JANX in my portfolio?

CADL and JANX have a correlation of 0.40, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CADL or JANX?

CADL has higher volatility (16.28%) compared to JANX (9.11%). In terms of maximum drawdown, CADL dropped -94.33% vs JANX's -83.14%.

Which has better risk-adjusted returns?

CADL currently has the higher Sharpe Ratio (0.73 vs -0.63), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.