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BTEK.L vs. VUSA.L
Performance
Return for Risk
Drawdowns
Volatility
Dividends

BTEK.L vs. VUSA.L

Last updated Jun 5, 2026

BTEK.L (iShares Nasdaq US Biotechnology UCITS ETF) and VUSA.L (Vanguard S&P 500 UCITS ETF) are both exchange-traded funds - BTEK.L is a Health & Biotech Equities fund tracking the NASDAQ Biotechnology TR USD, while VUSA.L is a S&P 500 fund tracking the S&P 500 Index. Both are passively managed. Over the past 5 years, BTEK.L returned 5.85%/yr vs 14.94%/yr for VUSA.L. A 0.59 correlation means they provide meaningful diversification when combined. BTEK.L charges 0.35%/yr vs 0.07%/yr for VUSA.L.

Performance

BTEK.L vs. VUSA.L - Performance Comparison

The chart below illustrates the hypothetical performance of a £10,000 investment in iShares Nasdaq US Biotechnology UCITS ETF (BTEK.L) and Vanguard S&P 500 UCITS ETF (VUSA.L). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, BTEK.L achieves a 4.86% return, which is significantly lower than VUSA.L's 10.52% return.

BTEK.L

1D
3.56%
1M
2.25%
YTD
4.86%
6M
2.70%
1Y
43.15%
3Y*
10.19%
5Y*
5.85%
10Y*
—

VUSA.L

1D
0.03%
1M
5.52%
YTD
10.52%
6M
10.48%
1Y
29.10%
3Y*
19.01%
5Y*
14.94%
10Y*
16.07%
*Multi-year figures are annualized to reflect compound growth (CAGR)

BTEK.L vs. VUSA.L - Yearly Performance Comparison

2026 (YTD)202520242023202220212020201920182017
BTEK.L
iShares Nasdaq US Biotechnology UCITS ETF		4.86%23.81%-0.32%0.33%-1.55%0.90%23.11%21.63%-6.34%-3.31%
VUSA.L
Vanguard S&P 500 UCITS ETF		10.52%9.39%27.33%19.81%-9.02%30.98%13.66%26.54%-0.12%2.21%

Correlation

The correlation between BTEK.L and VUSA.L is 0.42, which is low. Their price movements are largely independent, making them effective diversification partners.

Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.42

Correlation (3Y)
Calculated over the trailing 3-year period

0.46

Correlation (5Y)
Calculated over the trailing 5-year period

0.50

Correlation (All Time)
Calculated using the full available price history since Oct 25, 2017

0.59

The correlation between BTEK.L and VUSA.L shifts across timeframes, from 0.42 (1 year) to 0.59 (all time), reflecting how their relationship changes across market environments.

BTEK.L vs. VUSA.L - Sectors Allocation Comparison

Sectors
BTEK.L
VUSA.L

Healthcare

100.0%
8.5%

Basic Materials

-

1.8%

Communication Services

-

11.3%

Consumer Cyclical

-

10.2%

Consumer Defensive

-

4.9%

Energy

-

3.5%

Financial Services

-

11.6%

Industrials

-

8.3%

Real Estate

-

1.9%

Technology

-

35.7%

Utilities

-

2.4%

Healthcare

BTEK.L
100.0%
VUSA.L
8.5%

Basic Materials

BTEK.L

-

VUSA.L
1.8%

Communication Services

BTEK.L

-

VUSA.L
11.3%

Consumer Cyclical

BTEK.L

-

VUSA.L
10.2%

Consumer Defensive

BTEK.L

-

VUSA.L
4.9%

Energy

BTEK.L

-

VUSA.L
3.5%

Financial Services

BTEK.L

-

VUSA.L
11.6%

Industrials

BTEK.L

-

VUSA.L
8.3%

Real Estate

BTEK.L

-

VUSA.L
1.9%

Technology

BTEK.L

-

VUSA.L
35.7%

Utilities

BTEK.L

-

VUSA.L
2.4%

Compare stocks, funds, or ETFs

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iShares Nasdaq US Biotechnology UCITS ETF

Vanguard S&P 500 UCITS ETF

Often compared with BTEK.L:
BTEK.L vs. SBIO.LBTEK.L vs. BRK-BBTEK.L vs. IBBQBTEK.L vs. XLKBTEK.L vs. QQQBTEK.L vs. GOOGBTEK.L vs. BTC-USD
Often compared with VUSA.L:
VUSA.L vs. CSPX.ASVUSA.L vs. VOOVUSA.L vs. VWRL.LVUSA.L vs. SGLN.LVUSA.L vs. VNRT.LVUSA.L vs. VUSA.DEVUSA.L vs. VUKE.L

Return for Risk

BTEK.L vs. VUSA.L — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.
BTEK.L
BTEK.L Risk / Return Rank: 7676
Overall Rank
BTEK.L Sharpe Ratio Rank: 7070
Sharpe Ratio Rank
BTEK.L Sortino Ratio Rank: 7070
Sortino Ratio Rank
BTEK.L Omega Ratio Rank: 6363
Omega Ratio Rank
BTEK.L Calmar Ratio Rank: 9292
Calmar Ratio Rank
BTEK.L Martin Ratio Rank: 8585
Martin Ratio Rank
VUSA.L
VUSA.L Risk / Return Rank: 8282
Overall Rank
VUSA.L Sharpe Ratio Rank: 8484
Sharpe Ratio Rank
VUSA.L Sortino Ratio Rank: 8383
Sortino Ratio Rank
VUSA.L Omega Ratio Rank: 8585
Omega Ratio Rank
VUSA.L Calmar Ratio Rank: 8080
Calmar Ratio Rank
VUSA.L Martin Ratio Rank: 7878
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BTEK.L vs. VUSA.L - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Nasdaq US Biotechnology UCITS ETF (BTEK.L) and Vanguard S&P 500 UCITS ETF (VUSA.L). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

BTEK.LVUSA.LDifference
Sharpe ratioReturn per unit of total volatility
2.24
2.74

-0.49

Sortino ratioReturn per unit of downside risk
3.13
3.68

-0.54

Omega ratioGain probability vs. loss probability

1.38

1.51

-0.14

Calmar ratioReturn relative to maximum drawdown

6.23

4.08

+2.16

Martin ratioReturn relative to average drawdown

17.55

15.02

+2.53

Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

BTEK.L vs. VUSA.L - Sharpe Ratio Comparison

The current BTEK.L Sharpe Ratio is 2.24, which is comparable to the VUSA.L Sharpe Ratio of 2.74. The chart below compares the historical Sharpe Ratios of BTEK.L and VUSA.L, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

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Sharpe Ratios by Period

BTEK.LVUSA.LDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

2.24

2.74

-0.49

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.29

1.04

-0.75

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

—

1.03

—

Sharpe Ratio (All Time)

Calculated using the full available price history

0.31

1.06

-0.75

Drawdowns

BTEK.L vs. VUSA.L - Drawdown Comparison

The maximum BTEK.L drawdown since its inception was -30.86%, which is greater than VUSA.L's maximum drawdown of -25.47%. Use the drawdown chart below to compare losses from any high point for BTEK.L and VUSA.L.

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Drawdown Indicators

BTEK.LVUSA.LDifference

Max Drawdown

Largest peak-to-trough decline

-30.86%

-25.47%

-5.39%

Max Drawdown (1Y)

Largest decline over 1 year

-6.89%

-7.11%

+0.22%

Max Drawdown (3Y)

Largest decline over 3 years

-26.34%

-20.94%

-5.40%

Max Drawdown (5Y)

Largest decline over 5 years

-30.86%

-20.94%

-9.92%

Max Drawdown (10Y)

Largest decline over 10 years

—

-25.47%

—

Current Drawdown

Current decline from peak

-1.86%

-0.23%

-1.63%

Average Drawdown

Average peak-to-trough decline

-10.04%

-3.19%

-6.85%

Ulcer Index

Depth and duration of drawdowns from previous peaks

2.45%

1.93%

+0.52%

Volatility

BTEK.L vs. VUSA.L - Volatility Comparison

iShares Nasdaq US Biotechnology UCITS ETF (BTEK.L) has a higher volatility of 6.91% compared to Vanguard S&P 500 UCITS ETF (VUSA.L) at 2.63%. This indicates that BTEK.L's price experiences larger fluctuations and is considered to be riskier than VUSA.L based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

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Volatility by Period

BTEK.LVUSA.LDifference

Volatility (1M)

Calculated over the trailing 1-month period

6.91%

2.63%

+4.28%

Volatility (6M)

Calculated over the trailing 6-month period

14.67%

7.12%

+7.55%

Volatility (1Y)

Calculated over the trailing 1-year period

19.14%

10.58%

+8.56%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

20.08%

14.29%

+5.79%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

21.71%

15.64%

+6.07%

BTEK.L vs. VUSA.L - Expense Ratio Comparison

BTEK.L has a 0.35% expense ratio, which is higher than VUSA.L's 0.07% expense ratio.

Dividends

BTEK.L vs. VUSA.L - Dividend Comparison

BTEK.L has not paid dividends to shareholders, while VUSA.L's dividend yield for the trailing twelve months is around 0.87%.

PositionTTM20252024202320222021202020192018201720162015
BTEK.L
iShares Nasdaq US Biotechnology UCITS ETF		0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
VUSA.L
Vanguard S&P 500 UCITS ETF		0.87%0.95%1.00%1.24%1.41%1.04%1.44%1.50%1.72%1.61%1.58%1.73%

Frequently Asked Questions

BTEK.L and VUSA.L have a correlation of 0.42, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

On fees, VUSA.L is cheaper at 0.07% per year. The better choice depends on whether you care most about return, fees, risk, or income.

VUSA.L is cheaper with a 0.07% expense ratio, compared with 0.35% for BTEK.L.

BTEK.L is categorized as Health & Biotech Equities, while VUSA.L is S&P 500. BTEK.L tracks NASDAQ Biotechnology TR USD, while VUSA.L tracks S&P 500 Index. They also come from different issuers: iShares and Vanguard. Their fees differ too: 0.35% for BTEK.L and 0.07% for VUSA.L.

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