BTEC vs. WDNA

Last updated Apr 1, 2026

Compare and contrast key facts about Principal Healthcare Innovators Index ETF (BTEC) and WisdomTree BioRevolution Fund (WDNA).

BTEC and WDNA are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. BTEC is a passively managed fund by Principal that tracks the performance of the NASDAQ U.S. Health Care Innovators Index. It was launched on Aug 19, 2016. WDNA is a passively managed fund by WisdomTree that tracks the performance of the WisdomTree BioRevolution Index. It was launched on Jun 3, 2021. Both BTEC and WDNA are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

BTEC vs. WDNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Principal Healthcare Innovators Index ETF (BTEC) and WisdomTree BioRevolution Fund (WDNA). The values are adjusted to include any dividend payments, if applicable.

BTEC vs. WDNA - Yearly Performance Comparison

	2026 (YTD)
BTEC Principal Healthcare Innovators Index ETF	0.00%
WDNA WisdomTree BioRevolution Fund	-2.74%

Returns By Period

BTEC

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

WDNA

• 1D: 4.08%
• 1M: -4.89%
• YTD: 2.99%
• 6M: 14.31%
• 1Y: 41.33%
• 3Y*: 2.41%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

BTEC vs. WDNA - Expense Ratio Comparison

BTEC has a 0.42% expense ratio, which is lower than WDNA's 0.45% expense ratio.

WDNA

WisdomTree BioRevolution Fund

BTEC

Principal Healthcare Innovators Index ETF

Return for Risk

BTEC vs. WDNA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

WDNA

WDNA Risk / Return Rank: 78
WDNA Sharpe Ratio Rank: 77
WDNA Sortino Ratio Rank: 80
WDNA Omega Ratio Rank: 67
WDNA Calmar Ratio Rank: 91
WDNA Martin Ratio Rank: 73

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BTEC vs. WDNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Principal Healthcare Innovators Index ETF (BTEC) and WisdomTree BioRevolution Fund (WDNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	BTEC	WDNA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	1.40	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	-0.24	—

Dividends

BTEC vs. WDNA - Dividend Comparison

BTEC has not paid dividends to shareholders, while WDNA's dividend yield for the trailing twelve months is around 4.43%.

	TTM	2025	2024	2023	2022	2021
BTEC Principal Healthcare Innovators Index ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
WDNA WisdomTree BioRevolution Fund	4.43%	4.57%	0.75%	0.80%	0.38%	0.10%

Drawdowns

BTEC vs. WDNA - Drawdown Comparison

The maximum BTEC drawdown since its inception was 0.00%, smaller than the maximum WDNA drawdown of -58.87%. Use the drawdown chart below to compare losses from any high point for BTEC and WDNA.

Drawdown Indicators

	BTEC	WDNA	Difference
Max Drawdown Largest peak-to-trough decline	0.00%	-58.87%	+58.87%
Max Drawdown (1Y) Largest decline over 1 year	—	-11.70%	—
Current Drawdown Current decline from peak	0.00%	-33.71%	+33.71%
Average Drawdown Average peak-to-trough decline	0.00%	-35.79%	+35.79%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	5.20%	—

Volatility

Volatility by Period

	BTEC	WDNA	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	8.88%	—
Volatility (6M) Calculated over the trailing 6-month period	—	18.59%	—
Volatility (1Y) Calculated over the trailing 1-year period	0.00%	29.63%	-29.63%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	0.00%	25.17%	-25.17%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	0.00%	25.17%	-25.17%