BTEC vs. BBC

Last updated Apr 1, 2026

Compare and contrast key facts about Principal Healthcare Innovators Index ETF (BTEC) and Virtus LifeSci Biotech Clinical Trials ETF (BBC).

BTEC and BBC are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. BTEC is a passively managed fund by Principal that tracks the performance of the NASDAQ U.S. Health Care Innovators Index. It was launched on Aug 19, 2016. BBC is a passively managed fund by Virtus Investment Partners that tracks the performance of the LifeSci Biotechnology Clinical Trials Index. It was launched on Dec 16, 2014. Both BTEC and BBC are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

BTEC vs. BBC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Principal Healthcare Innovators Index ETF (BTEC) and Virtus LifeSci Biotech Clinical Trials ETF (BBC). The values are adjusted to include any dividend payments, if applicable.

BTEC vs. BBC - Yearly Performance Comparison

	2026 (YTD)
BTEC Principal Healthcare Innovators Index ETF	0.00%
BBC Virtus LifeSci Biotech Clinical Trials ETF	1.84%

Returns By Period

BTEC

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

BBC

• 1D: 7.67%
• 1M: -1.98%
• YTD: 7.95%
• 6M: 55.07%
• 1Y: 141.32%
• 3Y*: 25.09%
• 5Y*: -3.63%
• 10Y*: 8.41%

*Multi-year figures are annualized to reflect compound growth (CAGR)

BTEC vs. BBC - Expense Ratio Comparison

BTEC has a 0.42% expense ratio, which is lower than BBC's 0.79% expense ratio.

BBC

Virtus LifeSci Biotech Clinical Trials ETF

BTEC

Principal Healthcare Innovators Index ETF

Return for Risk

BTEC vs. BBC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BBC

BBC Risk / Return Rank: 97
BBC Sharpe Ratio Rank: 98
BBC Sortino Ratio Rank: 97
BBC Omega Ratio Rank: 95
BBC Calmar Ratio Rank: 98
BBC Martin Ratio Rank: 98

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BTEC vs. BBC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Principal Healthcare Innovators Index ETF (BTEC) and Virtus LifeSci Biotech Clinical Trials ETF (BBC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	BTEC	BBC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	3.52	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.09	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.22	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	0.12	—

Dividends

BTEC vs. BBC - Dividend Comparison

BTEC has not paid dividends to shareholders, while BBC's dividend yield for the trailing twelve months is around 1.57%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
BTEC Principal Healthcare Innovators Index ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
BBC Virtus LifeSci Biotech Clinical Trials ETF	1.57%	1.70%	1.00%	0.34%	0.00%	0.00%	0.00%	0.00%	0.00%	2.09%	0.00%	0.51%

Drawdowns

BTEC vs. BBC - Drawdown Comparison

The maximum BTEC drawdown since its inception was 0.00%, smaller than the maximum BBC drawdown of -76.85%. Use the drawdown chart below to compare losses from any high point for BTEC and BBC.

Drawdown Indicators

	BTEC	BBC	Difference
Max Drawdown Largest peak-to-trough decline	0.00%	-76.85%	+76.85%
Max Drawdown (1Y) Largest decline over 1 year	—	-18.03%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-72.58%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-76.85%	—
Current Drawdown Current decline from peak	0.00%	-30.71%	+30.71%
Average Drawdown Average peak-to-trough decline	0.00%	-37.30%	+37.30%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	5.05%	—

Volatility

Volatility by Period

	BTEC	BBC	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	13.21%	—
Volatility (6M) Calculated over the trailing 6-month period	—	26.93%	—
Volatility (1Y) Calculated over the trailing 1-year period	0.00%	40.92%	-40.92%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	0.00%	39.30%	-39.30%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	0.00%	37.86%	-37.86%