BBC vs. MDEV
Compare and contrast key facts about Virtus LifeSci Biotech Clinical Trials ETF (BBC) and First Trust Indxx Medical Devices ETF (MDEV).
BBC and MDEV are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. BBC is a passively managed fund by Virtus Investment Partners that tracks the performance of the LifeSci Biotechnology Clinical Trials Index. It was launched on Dec 16, 2014. MDEV is a passively managed fund by First Trust that tracks the performance of the Indxx Global Medical Equipment Index. It was launched on Jun 22, 2021. Both BBC and MDEV are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.
Performance
BBC vs. MDEV - Performance Comparison
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BBC vs. MDEV - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
BBC Virtus LifeSci Biotech Clinical Trials ETF | 10.01% | 63.77% | -1.11% | -1.80% | -35.13% | -22.29% |
MDEV First Trust Indxx Medical Devices ETF | -8.91% | 2.00% | 1.79% | 7.55% | -28.59% | 4.16% |
Returns By Period
In the year-to-date period, BBC achieves a 10.01% return, which is significantly higher than MDEV's -8.91% return.
BBC
- 1D
- 1.91%
- 1M
- 0.45%
- YTD
- 10.01%
- 6M
- 58.07%
- 1Y
- 160.96%
- 3Y*
- 25.88%
- 5Y*
- -3.27%
- 10Y*
- 8.62%
MDEV
- 1D
- 0.55%
- 1M
- -7.19%
- YTD
- -8.91%
- 6M
- -5.62%
- 1Y
- -4.32%
- 3Y*
- -2.10%
- 5Y*
- —
- 10Y*
- —
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BBC vs. MDEV - Expense Ratio Comparison
BBC has a 0.79% expense ratio, which is higher than MDEV's 0.70% expense ratio.
Return for Risk
BBC vs. MDEV — Risk / Return Rank
BBC
MDEV
BBC vs. MDEV - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Virtus LifeSci Biotech Clinical Trials ETF (BBC) and First Trust Indxx Medical Devices ETF (MDEV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| BBC | MDEV | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 4.05 | -0.23 | +4.28 |
Sortino ratioReturn per unit of downside risk | 4.28 | -0.20 | +4.48 |
Omega ratioGain probability vs. loss probability | 1.53 | 0.98 | +0.55 |
Calmar ratioReturn relative to maximum drawdown | 8.09 | -0.35 | +8.44 |
Martin ratioReturn relative to average drawdown | 29.69 | -1.10 | +30.80 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| BBC | MDEV | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 4.05 | -0.23 | +4.28 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.08 | — | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.23 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.12 | -0.30 | +0.42 |
Correlation
The correlation between BBC and MDEV is 0.53, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.
Dividends
BBC vs. MDEV - Dividend Comparison
BBC's dividend yield for the trailing twelve months is around 1.55%, while MDEV has not paid dividends to shareholders.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
BBC Virtus LifeSci Biotech Clinical Trials ETF | 1.55% | 1.70% | 1.00% | 0.34% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 2.09% | 0.00% | 0.51% |
MDEV First Trust Indxx Medical Devices ETF | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Drawdowns
BBC vs. MDEV - Drawdown Comparison
The maximum BBC drawdown since its inception was -76.85%, which is greater than MDEV's maximum drawdown of -42.34%. Use the drawdown chart below to compare losses from any high point for BBC and MDEV.
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Drawdown Indicators
| BBC | MDEV | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -76.85% | -42.34% | -34.51% |
Max Drawdown (1Y)Largest decline over 1 year | -18.03% | -14.88% | -3.15% |
Max Drawdown (5Y)Largest decline over 5 years | -72.58% | — | — |
Max Drawdown (10Y)Largest decline over 10 years | -76.85% | — | — |
Current DrawdownCurrent decline from peak | -29.38% | -31.83% | +2.45% |
Average DrawdownAverage peak-to-trough decline | -37.30% | -25.40% | -11.90% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.91% | 4.70% | +0.21% |
Volatility
BBC vs. MDEV - Volatility Comparison
Virtus LifeSci Biotech Clinical Trials ETF (BBC) has a higher volatility of 13.12% compared to First Trust Indxx Medical Devices ETF (MDEV) at 5.62%. This indicates that BBC's price experiences larger fluctuations and is considered to be riskier than MDEV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| BBC | MDEV | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 13.12% | 5.62% | +7.50% |
Volatility (6M)Calculated over the trailing 6-month period | 26.96% | 10.78% | +16.18% |
Volatility (1Y)Calculated over the trailing 1-year period | 40.44% | 18.99% | +21.45% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 39.31% | 18.99% | +20.32% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 37.86% | 18.99% | +18.87% |