AXSM vs. TVTX
AXSM (Axsome Therapeutics, Inc.) and TVTX (Travere Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, AXSM returned 39.88%/yr vs 10.47%/yr for TVTX. At a 0.30 correlation, their price movements are largely independent.
Performance
AXSM vs. TVTX - Performance Comparison
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Returns By Period
In the year-to-date period, AXSM achieves a 28.75% return, which is significantly higher than TVTX's 23.21% return. Over the past 10 years, AXSM has outperformed TVTX with an annualized return of 39.88%, while TVTX has yielded a comparatively lower 10.47% annualized return.
AXSM
- 1D
- 1.21%
- 1M
- 8.17%
- YTD
- 28.75%
- 6M
- 59.35%
- 1Y
- 110.12%
- 3Y*
- 47.19%
- 5Y*
- 29.93%
- 10Y*
- 39.88%
TVTX
- 1D
- 2.77%
- 1M
- 10.52%
- YTD
- 23.21%
- 6M
- 37.30%
- 1Y
- 207.31%
- 3Y*
- 41.35%
- 5Y*
- 25.91%
- 10Y*
- 10.47%
AXSM vs. TVTX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 28.75% | 115.86% | 6.31% | 3.19% | 104.16% | -53.63% | -21.18% | 3,565.25% | -49.64% | -17.04% |
TVTX Travere Therapeutics, Inc. | 23.21% | 119.35% | 93.77% | -57.25% | -32.25% | 13.89% | 91.94% | -37.25% | 7.40% | 11.30% |
Correlation
The correlation between AXSM and TVTX is 0.37, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.37 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.36 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.35 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.31 |
Correlation (All Time) Calculated using the full available price history since Nov 20, 2015 | 0.30 |
Fundamentals
AXSM:
$12.04B
TVTX:
$4.33B
AXSM:
-$3.74
TVTX:
-$0.49
AXSM:
16.71
TVTX:
8.20
AXSM:
220.54
TVTX:
43.81
AXSM:
$708.24M
TVTX:
$536.20M
AXSM:
$655.82M
TVTX:
$385.20M
AXSM:
-$172.72M
TVTX:
$11.15M
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Return for Risk
AXSM vs. TVTX — Risk / Return Rank
AXSM
TVTX
AXSM vs. TVTX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Axsome Therapeutics, Inc. (AXSM) and Travere Therapeutics, Inc. (TVTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| AXSM | TVTX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.26 | ||
| Sortino ratioReturn per unit of downside risk | +0.16 | ||
| Omega ratioGain probability vs. loss probability | 1.47 | 1.48 | -0.01 |
| Calmar ratioReturn relative to maximum drawdown | 5.99 | 6.23 | -0.24 |
| Martin ratioReturn relative to average drawdown | 17.16 | 14.39 | +2.76 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| AXSM | TVTX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 2.65 | 2.92 | -0.26 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.43 | 0.39 | +0.04 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.44 | 0.18 | +0.26 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.40 | 0.30 | +0.10 |
Drawdowns
AXSM vs. TVTX - Drawdown Comparison
The maximum AXSM drawdown since its inception was -86.65%, roughly equal to the maximum TVTX drawdown of -85.43%. Use the drawdown chart below to compare losses from any high point for AXSM and TVTX.
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Drawdown Indicators
| AXSM | TVTX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -86.65% | -85.43% | -1.22% |
Max Drawdown (1Y)Largest decline over 1 year | -18.50% | -33.49% | +14.99% |
Max Drawdown (3Y)Largest decline over 3 years | -36.45% | -69.77% | +33.32% |
Max Drawdown (5Y)Largest decline over 5 years | -72.91% | -83.12% | +10.21% |
Max Drawdown (10Y)Largest decline over 10 years | -81.26% | -83.64% | +2.38% |
Current DrawdownCurrent decline from peak | -0.35% | -1.42% | +1.07% |
Average DrawdownAverage peak-to-trough decline | -39.55% | -41.13% | +1.58% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.56% | 14.49% | -7.93% |
Volatility
AXSM vs. TVTX - Volatility Comparison
The current volatility for Axsome Therapeutics, Inc. (AXSM) is 9.83%, while Travere Therapeutics, Inc. (TVTX) has a volatility of 14.17%. This indicates that AXSM experiences smaller price fluctuations and is considered to be less risky than TVTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AXSM | TVTX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 9.83% | 14.17% | -4.34% |
Volatility (6M)Calculated over the trailing 6-month period | 32.98% | 51.90% | -18.92% |
Volatility (1Y)Calculated over the trailing 1-year period | 41.79% | 71.68% | -29.89% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 70.31% | 66.44% | +3.87% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 90.68% | 58.34% | +32.34% |
Dividends
AXSM vs. TVTX - Dividend Comparison
Neither AXSM nor TVTX has paid dividends to shareholders.
Financials
AXSM vs. TVTX - Financials Comparison
This section allows you to compare key financial metrics between Axsome Therapeutics, Inc. and Travere Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AXSM vs. TVTX - Profitability Comparison
AXSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported a gross profit of 176.48M and revenue of 191.20M. Therefore, the gross margin over that period was 92.3%.
TVTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Travere Therapeutics, Inc. reported a gross profit of 0.00 and revenue of 127.20M. Therefore, the gross margin over that period was 0.0%.
AXSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported an operating income of -63.36M and revenue of 191.20M, resulting in an operating margin of -33.1%.
TVTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Travere Therapeutics, Inc. reported an operating income of -36.60M and revenue of 127.20M, resulting in an operating margin of -28.8%.
AXSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported a net income of -64.54M and revenue of 191.20M, resulting in a net margin of -33.8%.
TVTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Travere Therapeutics, Inc. reported a net income of -37.10M and revenue of 127.20M, resulting in a net margin of -29.2%.
Frequently Asked Questions
AXSM and TVTX have a correlation of 0.37, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TVTX has higher volatility (14.17%) compared to AXSM (9.83%). In terms of maximum drawdown, AXSM dropped -86.65% vs TVTX's -85.43%.
TVTX currently has the higher Sharpe Ratio (2.92 vs 2.65), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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