AXSM vs. CSCO
AXSM (Axsome Therapeutics, Inc.) and CSCO (Cisco Systems, Inc.) are both stocks. AXSM operates in Biotechnology (Healthcare), while CSCO operates in Communication Equipment (Technology). Over the past 10 years, AXSM returned 39.83%/yr vs 17.69%/yr for CSCO. Their 0.18 correlation means their historical movements had little consistent relationship.
Performance
AXSM vs. CSCO - Performance Comparison
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Returns By Period
In the year-to-date period, AXSM achieves a 19.36% return, which is significantly lower than CSCO's 52.77% return. Over the past 10 years, AXSM has outperformed CSCO with an annualized return of 39.83%, while CSCO has yielded a comparatively lower 17.69% annualized return.
AXSM
- 1D
- -7.10%
- 1M
- -9.42%
- 6M
- 18.31%
- YTD
- 19.36%
- 1Y
- 115.02%
- 3Y*
- 41.26%
- 5Y*
- 35.01%
- 10Y*
- 39.83%
- ALL TIME*
- 34.71%
CSCO
- 1D
- 2.14%
- 1M
- -0.50%
- 6M
- 49.46%
- YTD
- 52.77%
- 1Y
- 73.90%
- 3Y*
- 33.59%
- 5Y*
- 19.23%
- 10Y*
- 17.69%
- ALL TIME*
- 23.57%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $153.10M | $171.36M | $209.26M | |
| $2.18B | $2.38B | $2.92B |
AXSM vs. CSCO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 19.36% | 115.86% | 6.31% | 3.19% | 104.16% | -53.63% | -21.18% | 3,565.25% | -49.64% | -17.04% |
CSCO Cisco Systems, Inc. | 52.77% | 33.47% | 21.00% | 9.30% | -22.46% | 45.76% | -3.49% | 13.81% | 16.57% | 31.27% |
Correlation
The correlation between AXSM and CSCO is 0.07, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.07 |
Correlation (3Y) Balances recent behavior with more history. | 0.16 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.18 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.18 |
Correlation (All Time) Calculated using the full available price history since Nov 19, 2015 | 0.18 |
The correlation between AXSM and CSCO shifts across timeframes, from 0.07 (1 year) to 0.18 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
AXSM:
$11.22B
CSCO:
$457.17B
AXSM:
-$3.72
CSCO:
$3.00
AXSM:
15.58
CSCO:
7.62
AXSM:
204.46
CSCO:
9.46
AXSM:
$708.24M
CSCO:
$60.75B
AXSM:
$655.82M
CSCO:
$39.08B
AXSM:
-$172.72M
CSCO:
$13.98B
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Return for Risk
AXSM vs. CSCO — Risk / Return Rank
AXSM
CSCO
AXSM vs. CSCO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Axsome Therapeutics, Inc. (AXSM) and Cisco Systems, Inc. (CSCO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AXSM | CSCO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.43 | ||
| Sortino ratioReturn per unit of downside risk | +1.14 | ||
| Omega ratioGain probability vs. loss probability | 1.47 | 1.40 | +0.07 |
| Calmar ratioReturn relative to maximum drawdown | 6.25 | 4.85 | +1.41 |
| Martin ratioReturn relative to average drawdown | 18.02 | 11.72 | +6.30 |
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Drawdowns
AXSM vs. CSCO - Drawdown Comparison
The maximum AXSM drawdown since its inception was -86.65%, roughly equal to the maximum CSCO drawdown of -89.26%. Use the drawdown chart below to compare losses from any high point for AXSM and CSCO.
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Drawdown Indicators
| AXSM | CSCO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -86.65% | -89.26% | +2.61% |
Max Drawdown (1Y)Largest decline over 1 year | -18.50% | -15.33% | -3.17% |
Max Drawdown (3Y)Largest decline over 3 years | -32.69% | -20.16% | -12.53% |
Max Drawdown (5Y)Largest decline over 5 years | -61.08% | -36.68% | -24.40% |
Max Drawdown (10Y)Largest decline over 10 years | -81.26% | -41.95% | -39.31% |
Current DrawdownCurrent decline from peak | -14.57% | -10.44% | -4.13% |
Average DrawdownAverage peak-to-trough decline | -39.06% | -40.01% | +0.95% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.41% | 6.33% | +0.08% |
Volatility
AXSM vs. CSCO - Volatility Comparison
Axsome Therapeutics, Inc. (AXSM) has a higher volatility of 14.94% compared to Cisco Systems, Inc. (CSCO) at 10.19%. This indicates that AXSM's price experiences larger fluctuations and is considered to be riskier than CSCO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AXSM | CSCO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 14.94% | 10.19% | +4.75% |
Volatility (6M)Calculated over the trailing 6-month period | 28.72% | 29.00% | -0.28% |
Volatility (1Y)Calculated over the trailing 1-year period | 42.96% | 32.79% | +10.17% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 70.11% | 25.35% | +44.76% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 90.38% | 26.07% | +64.31% |
Dividends
AXSM vs. CSCO - Dividend Comparison
AXSM has not paid dividends to shareholders, while CSCO's dividend yield for the trailing twelve months is around 1.43%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
CSCO Cisco Systems, Inc. | 1.43% | 2.12% | 2.69% | 3.07% | 3.17% | 2.32% | 3.20% | 2.88% | 2.95% | 2.95% | 3.28% | 3.02% |
Financials
AXSM vs. CSCO - Financials Comparison
This section allows you to compare key financial metrics between Axsome Therapeutics, Inc. and Cisco Systems, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AXSM vs. CSCO - Profitability Comparison
AXSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Axsome Therapeutics, Inc. reported a gross profit of 176.48M and revenue of 191.20M. Therefore, the gross margin over that period was 92.3%.
CSCO - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Cisco Systems, Inc. reported a gross profit of 10.08B and revenue of 15.84B. Therefore, the gross margin over that period was 63.6%.
AXSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Axsome Therapeutics, Inc. reported an operating income of -63.36M and revenue of 191.20M, resulting in an operating margin of -33.1%.
CSCO - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Cisco Systems, Inc. reported an operating income of 3.96B and revenue of 15.84B, resulting in an operating margin of 25.0%.
AXSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Axsome Therapeutics, Inc. reported a net income of -64.54M and revenue of 191.20M, resulting in a net margin of -33.8%.
CSCO - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Cisco Systems, Inc. reported a net income of 3.37B and revenue of 15.84B, resulting in a net margin of 21.3%.
Frequently Asked Questions
AXSM and CSCO have a correlation of 0.07, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AXSM has higher volatility (14.94%) compared to CSCO (10.19%). In terms of maximum drawdown, AXSM dropped -86.65% vs CSCO's -89.26%.
AXSM currently has the higher Sharpe Ratio (2.69 vs 2.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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