ARVN vs. ARDX

Last updated Aug 1, 2026

ARVN (Arvinas, Inc.) and ARDX (Ardelyx, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, ARVN returned -39.75%/yr vs 23.26%/yr for ARDX. Their 0.34 correlation means their historical movements had little consistent relationship.

Performance

ARVN vs. ARDX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Arvinas, Inc. (ARVN) and Ardelyx, Inc. (ARDX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ARVN achieves a -32.29% return, which is significantly lower than ARDX's -15.09% return.

ARVN

• 1D: -3.25%
• 1M: -4.29%
• 6M: -39.99%
• YTD: -32.29%
• 1Y: 8.22%
• 3Y*: -31.39%
• 5Y*: -39.75%
• 10Y*: —
• ALL TIME*: -11.54%

ARDX

• 1D: -1.79%
• 1M: -6.07%
• 6M: -35.63%
• YTD: -15.09%
• 1Y: 14.32%
• 3Y*: 8.83%
• 5Y*: 23.26%
• 10Y*: -7.19%
• ALL TIME*: -8.49%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ARDX Ardelyx, Inc.	$11.70M	$13.98M	$21.62M
ARVN Arvinas, Inc.	$4.84M	$4.90M	$6.81M

ARVN vs. ARDX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
ARVN Arvinas, Inc.	-32.29%	-38.13%	-53.43%	20.32%	-58.35%	-3.29%	106.69%	219.77%	-38.81%
ARDX Ardelyx, Inc.	-15.09%	14.99%	-18.23%	117.54%	159.09%	-83.00%	-13.79%	319.27%	-59.78%

Correlation

The correlation between ARVN and ARDX is 0.29, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.29
Correlation (3Y) Balances recent behavior with more history.	0.33
Correlation (5Y) Shows whether the relationship held over a longer period.	0.37
Correlation (All Time) Calculated using the full available price history since Sep 27, 2018	0.34

Fundamentals

Market Cap ARVN : $518.11M ARDX : $1.22B
EPS ARVN : -$3.29 ARDX : -$0.24
PS Ratio ARVN : 6.04 ARDX : 2.82
PB Ratio ARVN : 1.33 ARDX : 8.19
Total Revenue (TTM) ARVN : $89.40M ARDX : $427.68M
Gross Profit (TTM) ARVN : $72.60M ARDX : $395.63M
EBITDA (TTM) ARVN : -$233.90M ARDX : -$28.55M

Return for Risk

ARVN vs. ARDX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ARVN

ARVN Risk / Return Rank: 49
ARVN Sharpe Ratio Rank: 51
ARVN Sortino Ratio Rank: 49
ARVN Omega Ratio Rank: 49
ARVN Calmar Ratio Rank: 50
ARVN Martin Ratio Rank: 49

ARDX

ARDX Risk / Return Rank: 56
ARDX Sharpe Ratio Rank: 55
ARDX Sortino Ratio Rank: 58
ARDX Omega Ratio Rank: 57
ARDX Calmar Ratio Rank: 56
ARDX Martin Ratio Rank: 56

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ARVN vs. ARDX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Arvinas, Inc. (ARVN) and Ardelyx, Inc. (ARDX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ARVN	ARDX	Difference
Sharpe ratio: Return per unit of total volatility	0.14	0.27	-0.13
Sortino ratio: Return per unit of downside risk	0.61	0.96	-0.35
Omega ratio: Gain probability vs. loss probability	1.08	1.11	-0.04
Calmar ratio: Return relative to maximum drawdown	0.16	0.44	-0.28
Martin ratio: Return relative to average drawdown	0.36	0.82	-0.45

ARVN vs. ARDX - Sharpe Ratio Comparison

The current ARVN Sharpe Ratio is 0.14, which is lower than the ARDX Sharpe Ratio of 0.27. The chart below compares the historical Sharpe Ratios of ARVN and ARDX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ARVN vs. ARDX - Drawdown Comparison

The maximum ARVN drawdown since its inception was -94.37%, roughly equal to the maximum ARDX drawdown of -98.45%. Use the drawdown chart below to compare losses from any high point for ARVN and ARDX.

Drawdown Indicators

	ARVN	ARDX	Difference
Max Drawdown Largest peak-to-trough decline	-94.37%	-98.45%	+4.08%
Max Drawdown (1Y) Largest decline over 1 year	-49.53%	-38.05%	-11.48%
Max Drawdown (3Y) Largest decline over 3 years	-88.40%	-66.32%	-22.08%
Max Drawdown (5Y) Largest decline over 5 years	-94.01%	-69.99%	-24.02%
Max Drawdown (10Y) Largest decline over 10 years	—	-96.82%	—
Current Drawdown Current decline from peak	-92.56%	-84.95%	-7.61%
Average Drawdown Average peak-to-trough decline	-52.69%	-77.43%	+24.74%
Ulcer Index Depth and duration of drawdowns from previous peaks	21.93%	20.58%	+1.35%

Volatility

ARVN vs. ARDX - Volatility Comparison

Arvinas, Inc. (ARVN) has a higher volatility of 8.40% compared to Ardelyx, Inc. (ARDX) at 7.66%. This indicates that ARVN's price experiences larger fluctuations and is considered to be riskier than ARDX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ARVN	ARDX	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.40%	7.66%	+0.74%
Volatility (6M) Calculated over the trailing 6-month period	35.09%	37.71%	-2.62%
Volatility (1Y) Calculated over the trailing 1-year period	55.21%	61.39%	-6.18%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	68.19%	82.75%	-14.56%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	77.60%	83.82%	-6.22%

Dividends

ARVN vs. ARDX - Dividend Comparison

Neither ARVN nor ARDX has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ARVN and ARDX in my portfolio?

ARVN and ARDX have a correlation of 0.29, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ARVN or ARDX?

ARVN has higher volatility (8.40%) compared to ARDX (7.66%). In terms of maximum drawdown, ARVN dropped -94.37% vs ARDX's -98.45%.

Which has better risk-adjusted returns?

ARDX currently has the higher Sharpe Ratio (0.27 vs 0.14), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.