ARGX vs. VDE

Last updated Jun 5, 2026

ARGX (argenx SE) is a stock, while VDE (Vanguard Energy ETF) is Energy Equities fund tracking the MSCI US Investable Market Energy 25/50 Index. Over the past 5 years, ARGX returned 25.56%/yr vs 20.47%/yr for VDE. At a 0.07 correlation, their price movements are largely independent.

Performance

ARGX vs. VDE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in argenx SE (ARGX) and Vanguard Energy ETF (VDE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ARGX achieves a 0.16% return, which is significantly lower than VDE's 32.48% return.

ARGX

• 1D: 3.58%
• 1M: 5.99%
• YTD: 0.16%
• 6M: -8.05%
• 1Y: 46.86%
• 3Y*: 27.88%
• 5Y*: 25.56%
• 10Y*: —

VDE

• 1D: 0.18%
• 1M: -1.99%
• YTD: 32.48%
• 6M: 28.99%
• 1Y: 48.54%
• 3Y*: 18.32%
• 5Y*: 20.47%
• 10Y*: 9.47%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ARGX vs. VDE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ARGX argenx SE	0.16%	36.74%	61.66%	0.42%	8.18%	19.08%	83.21%	67.09%	52.15%	174.52%
VDE Vanguard Energy ETF	32.48%	7.11%	6.75%	0.03%	62.89%	56.31%	-33.02%	9.28%	-19.95%	9.75%

Correlation

The correlation between ARGX and VDE is -0.20, meaning they tend to move in opposite directions. This is especially valuable for risk management - when one declines, the other has historically tended to hold steady or rise.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.20
Correlation (3Y) Calculated over the trailing 3-year period	-0.04
Correlation (5Y) Calculated over the trailing 5-year period	0.01
Correlation (All Time) Calculated using the full available price history since May 19, 2017	0.07

The correlation between ARGX and VDE shifts across timeframes, from -0.20 (1 year) to 0.07 (all time), reflecting how their relationship changes across market environments.

Return for Risk

ARGX vs. VDE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ARGX

ARGX Risk / Return Rank: 77
ARGX Sharpe Ratio Rank: 83
ARGX Sortino Ratio Rank: 81
ARGX Omega Ratio Rank: 78
ARGX Calmar Ratio Rank: 71
ARGX Martin Ratio Rank: 73

VDE

VDE Risk / Return Rank: 71
VDE Sharpe Ratio Rank: 75
VDE Sortino Ratio Rank: 68
VDE Omega Ratio Rank: 65
VDE Calmar Ratio Rank: 81
VDE Martin Ratio Rank: 67

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ARGX vs. VDE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for argenx SE (ARGX) and Vanguard Energy ETF (VDE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ARGX	VDE	Difference
Sharpe ratio: Return per unit of total volatility	1.57	2.41	-0.84
Sortino ratio: Return per unit of downside risk	2.33	3.06	-0.73
Omega ratio: Gain probability vs. loss probability	1.29	1.39	-0.10
Calmar ratio: Return relative to maximum drawdown	1.65	4.13	-2.49
Martin ratio: Return relative to average drawdown	4.36	12.11	-7.75
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ARGX vs. VDE - Sharpe Ratio Comparison

The current ARGX Sharpe Ratio is 1.57, which is lower than the VDE Sharpe Ratio of 2.41. The chart below compares the historical Sharpe Ratios of ARGX and VDE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ARGX	VDE	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.57	2.41	-0.84
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.66	0.78	-0.12
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.32	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.97	0.28	+0.69

Drawdowns

ARGX vs. VDE - Drawdown Comparison

The maximum ARGX drawdown since its inception was -38.20%, smaller than the maximum VDE drawdown of -74.20%. Use the drawdown chart below to compare losses from any high point for ARGX and VDE.

Drawdown Indicators

	ARGX	VDE	Difference
Max Drawdown Largest peak-to-trough decline	-38.20%	-74.20%	+36.00%
Max Drawdown (1Y) Largest decline over 1 year	-28.58%	-11.80%	-16.78%
Max Drawdown (3Y) Largest decline over 3 years	-38.20%	-21.41%	-16.79%
Max Drawdown (5Y) Largest decline over 5 years	-38.20%	-26.58%	-11.62%
Max Drawdown (10Y) Largest decline over 10 years	—	-69.29%	—
Current Drawdown Current decline from peak	-9.40%	-6.27%	-3.13%
Average Drawdown Average peak-to-trough decline	-11.10%	-19.96%	+8.86%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.77%	4.02%	+6.75%

Volatility

ARGX vs. VDE - Volatility Comparison

argenx SE (ARGX) has a higher volatility of 10.09% compared to Vanguard Energy ETF (VDE) at 7.99%. This indicates that ARGX's price experiences larger fluctuations and is considered to be riskier than VDE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ARGX	VDE	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.09%	7.99%	+2.10%
Volatility (6M) Calculated over the trailing 6-month period	21.20%	16.27%	+4.93%
Volatility (1Y) Calculated over the trailing 1-year period	29.93%	20.34%	+9.59%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	38.76%	26.40%	+12.36%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	50.67%	29.93%	+20.74%

Dividends

ARGX vs. VDE - Dividend Comparison

ARGX has not paid dividends to shareholders, while VDE's dividend yield for the trailing twelve months is around 2.37%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ARGX argenx SE	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VDE Vanguard Energy ETF	2.37%	3.11%	3.23%	3.34%	3.65%	4.13%	4.76%	3.42%	3.35%	2.90%	2.31%	3.17%

Frequently Asked Questions

Can I hold both ARGX and VDE in my portfolio?

ARGX and VDE have a correlation of -0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ARGX or VDE?

ARGX has higher volatility (10.09%) compared to VDE (7.99%). In terms of maximum drawdown, ARGX dropped -38.20% vs VDE's -74.20%.

Which has better risk-adjusted returns?

VDE currently has the higher Sharpe Ratio (2.41 vs 1.57), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.