APRE vs. EPR

Last updated Apr 1, 2026

Compare and contrast key facts about Aprea Therapeutics, Inc. (APRE) and EPR Properties (EPR).

Performance

APRE vs. EPR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Aprea Therapeutics, Inc. (APRE) and EPR Properties (EPR). The values are adjusted to include any dividend payments, if applicable.

APRE vs. EPR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
APRE Aprea Therapeutics, Inc.	-10.56%	-74.07%	-30.00%	-29.00%	-88.47%	-41.67%	-89.28%	123.85%
EPR EPR Properties	1.80%	20.52%	-1.25%	38.83%	-14.61%	50.60%	-52.09%	-7.23%

Fundamentals

Market Cap APRE : $5.87M EPR : $3.83B
EPS APRE : -$1.88 EPR : $3.59
PS Ratio APRE : 17.93 EPR : 5.33
PB Ratio APRE : 0.47 EPR : 1.64
Total Revenue (TTM) APRE : $285.76K EPR : $718.36M
Gross Profit (TTM) APRE : -$4.12M EPR : $716.16M
EBITDA (TTM) APRE : -$13.07M EPR : $579.67M

Returns By Period

In the year-to-date period, APRE achieves a -10.56% return, which is significantly lower than EPR's 1.80% return.

APRE

• 1D: 3.23%
• 1M: -16.78%
• YTD: -10.56%
• 6M: -48.28%
• 1Y: -62.60%
• 3Y*: -44.41%
• 5Y*: -62.35%
• 10Y*: —

EPR

• 1D: 2.00%
• 1M: -15.37%
• YTD: 1.80%
• 6M: -10.88%
• 1Y: 1.49%
• 3Y*: 17.71%
• 5Y*: 7.86%
• 10Y*: 3.25%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

APRE vs. EPR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

APRE

APRE Risk / Return Rank: 9
APRE Sharpe Ratio Rank: 10
APRE Sortino Ratio Rank: 9
APRE Omega Ratio Rank: 11
APRE Calmar Ratio Rank: 8
APRE Martin Ratio Rank: 7

EPR

EPR Risk / Return Rank: 42
EPR Sharpe Ratio Rank: 44
EPR Sortino Ratio Rank: 37
EPR Omega Ratio Rank: 37
EPR Calmar Ratio Rank: 47
EPR Martin Ratio Rank: 47

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

APRE vs. EPR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Aprea Therapeutics, Inc. (APRE) and EPR Properties (EPR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	APRE	EPR	Difference
Sharpe ratio Return per unit of total volatility	-0.75	0.06	-0.81
Sortino ratio Return per unit of downside risk	-1.19	0.26	-1.45
Omega ratio Gain probability vs. loss probability	0.87	1.03	-0.17
Calmar ratio Return relative to maximum drawdown	-0.89	0.20	-1.08
Martin ratio Return relative to average drawdown	-1.59	0.40	-1.99
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

APRE vs. EPR - Sharpe Ratio Comparison

The current APRE Sharpe Ratio is -0.75, which is lower than the EPR Sharpe Ratio of 0.06. The chart below compares the historical Sharpe Ratios of APRE and EPR, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	APRE	EPR	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.75	0.06	-0.81
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.74	0.29	-1.04
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.08	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.69	0.29	-0.98

Correlation

The correlation between APRE and EPR is 0.10, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

APRE vs. EPR - Dividend Comparison

APRE has not paid dividends to shareholders, while EPR's dividend yield for the trailing twelve months is around 7.12%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
APRE Aprea Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
EPR EPR Properties	7.12%	7.05%	7.68%	6.81%	8.62%	3.16%	4.66%	6.37%	5.62%	6.23%	5.35%	6.21%

Drawdowns

APRE vs. EPR - Drawdown Comparison

The maximum APRE drawdown since its inception was -99.94%, which is greater than EPR's maximum drawdown of -82.02%. Use the drawdown chart below to compare losses from any high point for APRE and EPR.

Drawdown Indicators

	APRE	EPR	Difference
Max Drawdown Largest peak-to-trough decline	-99.94%	-82.02%	-17.92%
Max Drawdown (1Y) Largest decline over 1 year	-71.63%	-19.51%	-52.12%
Max Drawdown (5Y) Largest decline over 5 years	-99.48%	-35.63%	-63.85%
Max Drawdown (10Y) Largest decline over 10 years	—	-82.02%	—
Current Drawdown Current decline from peak	-99.92%	-16.92%	-83.00%
Average Drawdown Average peak-to-trough decline	-85.00%	-16.66%	-68.34%
Ulcer Index Depth and duration of drawdowns from previous peaks	39.91%	9.66%	+30.25%

Volatility

APRE vs. EPR - Volatility Comparison

Aprea Therapeutics, Inc. (APRE) has a higher volatility of 22.02% compared to EPR Properties (EPR) at 8.43%. This indicates that APRE's price experiences larger fluctuations and is considered to be riskier than EPR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	APRE	EPR	Difference
Volatility (1M) Calculated over the trailing 1-month period	22.02%	8.43%	+13.59%
Volatility (6M) Calculated over the trailing 6-month period	66.41%	17.61%	+48.80%
Volatility (1Y) Calculated over the trailing 1-year period	83.70%	25.42%	+58.28%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	84.26%	26.91%	+57.35%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	89.50%	42.43%	+47.07%

Financials