APGE vs. RVMD

Last updated Aug 1, 2026

APGE (Apogee Therapeutics Inc. Common Stock) and RVMD (Revolution Medicines, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, APGE returned 84.27%/yr vs 81.24%/yr for RVMD. Their 0.41 correlation means their historical movements had little consistent relationship.

Performance

APGE vs. RVMD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Apogee Therapeutics Inc. Common Stock (APGE) and Revolution Medicines, Inc. (RVMD). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, APGE achieves a 77.65% return, which is significantly lower than RVMD's 135.44% return.

APGE

• 1D: -0.16%
• 1M: 0.89%
• 6M: 104.69%
• YTD: 77.65%
• 1Y: 255.21%
• 3Y*: 84.27%
• 5Y*: —
• 10Y*: —
• ALL TIME*: 82.34%

RVMD

• 1D: -2.41%
• 1M: -0.90%
• 6M: 93.43%
• YTD: 135.44%
• 1Y: 411.96%
• 3Y*: 81.24%
• 5Y*: 45.62%
• 10Y*: —
• ALL TIME*: 34.07%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
APGE Apogee Therapeutics Inc. Common Stock	$128.05M	$169.87M	$317.81M
RVMD Revolution Medicines, Inc.	$346.97M	$364.41M	$450.00M

APGE vs. RVMD - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
APGE Apogee Therapeutics Inc. Common Stock	77.65%	66.62%	62.13%	29.95%
RVMD Revolution Medicines, Inc.	135.44%	82.10%	52.51%	8.10%

Correlation

The correlation between APGE and RVMD is 0.44, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.44
Correlation (3Y) Balances recent behavior with more history.	0.41
Correlation (All Time) Calculated using the full available price history since Jul 14, 2023	0.41

Fundamentals

Market Cap APGE : $8.30B RVMD : $39.87B
EPS APGE : -$3.18 RVMD : -$7.13
PB Ratio APGE : 7.44 RVMD : 24.77
Total Revenue (TTM) APGE : $0.00 RVMD : $0.00
Gross Profit (TTM) APGE : $0.00 RVMD : -$4.70M
EBITDA (TTM) APGE : -$297.75M RVMD : -$1.34B

Return for Risk

APGE vs. RVMD — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

APGE

APGE Risk / Return Rank: 99
APGE Sharpe Ratio Rank: 98
APGE Sortino Ratio Rank: 99
APGE Omega Ratio Rank: 98
APGE Calmar Ratio Rank: 99
APGE Martin Ratio Rank: 99

RVMD

RVMD Risk / Return Rank: 99
RVMD Sharpe Ratio Rank: 100
RVMD Sortino Ratio Rank: 99
RVMD Omega Ratio Rank: 99
RVMD Calmar Ratio Rank: 99
RVMD Martin Ratio Rank: 99

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

APGE vs. RVMD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Apogee Therapeutics Inc. Common Stock (APGE) and Revolution Medicines, Inc. (RVMD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	APGE	RVMD	Difference
Sharpe ratio: Return per unit of total volatility	3.57	6.01	-2.45
Sortino ratio: Return per unit of downside risk	5.19	6.49	-1.30
Omega ratio: Gain probability vs. loss probability	1.67	1.93	-0.25
Calmar ratio: Return relative to maximum drawdown	10.24	16.29	-6.05
Martin ratio: Return relative to average drawdown	31.57	40.39	-8.81

APGE vs. RVMD - Sharpe Ratio Comparison

The current APGE Sharpe Ratio is 3.57, which is lower than the RVMD Sharpe Ratio of 6.01. The chart below compares the historical Sharpe Ratios of APGE and RVMD, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

APGE vs. RVMD - Drawdown Comparison

The maximum APGE drawdown since its inception was -58.75%, smaller than the maximum RVMD drawdown of -73.29%. Use the drawdown chart below to compare losses from any high point for APGE and RVMD.

Drawdown Indicators

	APGE	RVMD	Difference
Max Drawdown Largest peak-to-trough decline	-58.75%	-73.29%	+14.54%
Max Drawdown (1Y) Largest decline over 1 year	-24.63%	-24.95%	+0.32%
Max Drawdown (3Y) Largest decline over 3 years	-58.75%	-48.63%	-10.12%
Max Drawdown (5Y) Largest decline over 5 years	—	-56.85%	—
Current Drawdown Current decline from peak	-0.16%	-2.64%	+2.48%
Average Drawdown Average peak-to-trough decline	-23.26%	-35.01%	+11.75%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.97%	10.04%	-2.07%

Volatility

APGE vs. RVMD - Volatility Comparison

The current volatility for Apogee Therapeutics Inc. Common Stock (APGE) is 0.70%, while Revolution Medicines, Inc. (RVMD) has a volatility of 10.50%. This indicates that APGE experiences smaller price fluctuations and is considered to be less risky than RVMD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	APGE	RVMD	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.70%	10.50%	-9.80%
Volatility (6M) Calculated over the trailing 6-month period	52.57%	45.53%	+7.04%
Volatility (1Y) Calculated over the trailing 1-year period	70.76%	67.61%	+3.15%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	71.00%	62.48%	+8.52%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	71.00%	65.34%	+5.66%

Dividends

APGE vs. RVMD - Dividend Comparison

Neither APGE nor RVMD has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both APGE and RVMD in my portfolio?

APGE and RVMD have a correlation of 0.44, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, APGE or RVMD?

RVMD has higher volatility (10.50%) compared to APGE (0.70%). In terms of maximum drawdown, APGE dropped -58.75% vs RVMD's -73.29%.

Which has better risk-adjusted returns?

RVMD currently has the higher Sharpe Ratio (6.01 vs 3.57), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.