AMPH vs. MSFT
AMPH (Amphastar Pharmaceuticals, Inc.) and MSFT (Microsoft Corporation) are both stocks. AMPH operates in Drug Manufacturers - Specialty & Generic (Healthcare), while MSFT operates in Software - Infrastructure (Technology). Over the past 10 years, AMPH returned 2.48%/yr vs 24.39%/yr for MSFT. At a 0.21 correlation, their price movements are largely independent.
Performance
AMPH vs. MSFT - Performance Comparison
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Returns By Period
In the year-to-date period, AMPH achieves a -24.98% return, which is significantly lower than MSFT's -18.85% return. Over the past 10 years, AMPH has underperformed MSFT with an annualized return of 2.48%, while MSFT has yielded a comparatively higher 24.39% annualized return.
AMPH
- 1D
- -2.14%
- 1M
- 16.13%
- YTD
- -24.98%
- 6M
- -20.50%
- 1Y
- -22.19%
- 3Y*
- -24.72%
- 5Y*
- 0.17%
- 10Y*
- 2.48%
MSFT
- 1D
- 0.10%
- 1M
- -4.36%
- YTD
- -18.85%
- 6M
- -17.98%
- 1Y
- -17.07%
- 3Y*
- 6.16%
- 5Y*
- 9.56%
- 10Y*
- 24.39%
AMPH vs. MSFT - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AMPH Amphastar Pharmaceuticals, Inc. | -24.98% | -27.88% | -39.97% | 120.74% | 20.31% | 15.81% | 4.25% | -3.07% | 3.43% | 4.45% |
MSFT Microsoft Corporation | -18.85% | 15.58% | 12.93% | 58.19% | -28.02% | 52.48% | 42.53% | 57.56% | 20.80% | 40.73% |
Correlation
The correlation between AMPH and MSFT is 0.06, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.06 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.10 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.13 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.21 |
Correlation (All Time) Calculated using the full available price history since Jun 25, 2014 | 0.21 |
The correlation between AMPH and MSFT shifts across timeframes, from 0.06 (1 year) to 0.21 (all time), reflecting how their relationship changes across market environments.
Fundamentals
AMPH:
$933.34M
MSFT:
$2.91T
AMPH:
$1.67
MSFT:
$16.79
AMPH:
12.01
MSFT:
23.27
AMPH:
0.64
MSFT:
1.63
AMPH:
1.32
MSFT:
9.16
AMPH:
1.21
MSFT:
7.02
AMPH:
$720.53M
MSFT:
$318.27B
AMPH:
$341.13M
MSFT:
$217.41B
AMPH:
$155.96M
MSFT:
$200.96B
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Return for Risk
AMPH vs. MSFT — Risk / Return Rank
AMPH
MSFT
AMPH vs. MSFT - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Amphastar Pharmaceuticals, Inc. (AMPH) and Microsoft Corporation (MSFT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AMPH | MSFT | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.25 | ||
| Sortino ratioReturn per unit of downside risk | +0.54 | ||
| Omega ratioGain probability vs. loss probability | 0.95 | 0.89 | +0.06 |
| Calmar ratioReturn relative to maximum drawdown | -0.53 | -0.53 | -0.01 |
| Martin ratioReturn relative to average drawdown | -1.07 | -1.08 | +0.01 |
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Drawdowns
AMPH vs. MSFT - Drawdown Comparison
The maximum AMPH drawdown since its inception was -74.05%, which is greater than MSFT's maximum drawdown of -69.38%. Use the drawdown chart below to compare losses from any high point for AMPH and MSFT.
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Drawdown Indicators
| AMPH | MSFT | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -74.05% | -69.38% | -4.67% |
Max Drawdown (1Y)Largest decline over 1 year | -45.25% | -33.91% | -11.34% |
Max Drawdown (3Y)Largest decline over 3 years | -74.05% | -33.91% | -40.14% |
Max Drawdown (5Y)Largest decline over 5 years | -74.05% | -37.15% | -36.90% |
Max Drawdown (10Y)Largest decline over 10 years | -74.05% | -37.15% | -36.90% |
Current DrawdownCurrent decline from peak | -69.09% | -27.46% | -41.63% |
Average DrawdownAverage peak-to-trough decline | -24.08% | -21.78% | -2.30% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 22.54% | 16.48% | +6.06% |
Volatility
AMPH vs. MSFT - Volatility Comparison
Amphastar Pharmaceuticals, Inc. (AMPH) has a higher volatility of 12.20% compared to Microsoft Corporation (MSFT) at 10.52%. This indicates that AMPH's price experiences larger fluctuations and is considered to be riskier than MSFT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AMPH | MSFT | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 12.20% | 10.52% | +1.68% |
Volatility (6M)Calculated over the trailing 6-month period | 46.17% | 22.31% | +23.86% |
Volatility (1Y)Calculated over the trailing 1-year period | 53.78% | 25.42% | +28.36% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 45.07% | 26.66% | +18.41% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 42.71% | 27.06% | +15.65% |
Dividends
AMPH vs. MSFT - Dividend Comparison
AMPH has not paid dividends to shareholders, while MSFT's dividend yield for the trailing twelve months is around 0.91%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMPH Amphastar Pharmaceuticals, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
MSFT Microsoft Corporation | 0.91% | 0.70% | 0.73% | 0.74% | 1.06% | 0.68% | 0.94% | 1.20% | 1.69% | 1.86% | 2.37% | 2.33% |
Financials
AMPH vs. MSFT - Financials Comparison
This section allows you to compare key financial metrics between Amphastar Pharmaceuticals, Inc. and Microsoft Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AMPH vs. MSFT - Profitability Comparison
AMPH - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Amphastar Pharmaceuticals, Inc. reported a gross profit of 70.32M and revenue of 171.17M. Therefore, the gross margin over that period was 41.1%.
MSFT - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported a gross profit of 56.06B and revenue of 82.89B. Therefore, the gross margin over that period was 67.6%.
AMPH - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Amphastar Pharmaceuticals, Inc. reported an operating income of 13.63M and revenue of 171.17M, resulting in an operating margin of 8.0%.
MSFT - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported an operating income of 38.40B and revenue of 82.89B, resulting in an operating margin of 46.3%.
AMPH - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Amphastar Pharmaceuticals, Inc. reported a net income of 6.42M and revenue of 171.17M, resulting in a net margin of 3.8%.
MSFT - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported a net income of 31.78B and revenue of 82.89B, resulting in a net margin of 38.3%.
Frequently Asked Questions
AMPH and MSFT have a correlation of 0.06, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AMPH has higher volatility (12.20%) compared to MSFT (10.52%). In terms of maximum drawdown, AMPH dropped -74.05% vs MSFT's -69.38%.
AMPH currently has the higher Sharpe Ratio (-0.45 vs -0.70), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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