ALXO vs. OPEN

Last updated Apr 1, 2026

Compare and contrast key facts about ALX Oncology Holdings Inc. (ALXO) and Opendoor Technologies Inc. (OPEN).

Performance

ALXO vs. OPEN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ALX Oncology Holdings Inc. (ALXO) and Opendoor Technologies Inc. (OPEN). The values are adjusted to include any dividend payments, if applicable.

ALXO vs. OPEN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ALXO ALX Oncology Holdings Inc.	77.43%	-32.34%	-88.78%	32.12%	-47.56%	-75.07%	187.33%
OPEN Opendoor Technologies Inc.	-19.73%	276.52%	-64.29%	286.21%	-92.06%	-35.72%	89.42%

Fundamentals

Market Cap ALXO : $108.84M OPEN : $3.59B
EPS ALXO : -$1.89 OPEN : -$1.74
PB Ratio ALXO : 4.19 OPEN : 3.57
Total Revenue (TTM) ALXO : $0.00 OPEN : $4.37B
Gross Profit (TTM) ALXO : $0.00 OPEN : $350.00M
EBITDA (TTM) ALXO : -$100.09M OPEN : -$287.00M

Returns By Period

In the year-to-date period, ALXO achieves a 77.43% return, which is significantly higher than OPEN's -19.73% return.

ALXO

• 1D: 4.97%
• 1M: -4.98%
• YTD: 77.43%
• 6M: 9.56%
• 1Y: 221.83%
• 3Y*: -23.73%
• 5Y*: -51.43%
• 10Y*: —

OPEN

• 1D: 5.64%
• 1M: -13.65%
• YTD: -19.73%
• 6M: -39.32%
• 1Y: 374.12%
• 3Y*: 40.06%
• 5Y*: -25.97%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ALXO vs. OPEN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ALXO

ALXO Risk / Return Rank: 88
ALXO Sharpe Ratio Rank: 89
ALXO Sortino Ratio Rank: 90
ALXO Omega Ratio Rank: 83
ALXO Calmar Ratio Rank: 91
ALXO Martin Ratio Rank: 86

OPEN

OPEN Risk / Return Rank: 92
OPEN Sharpe Ratio Rank: 93
OPEN Sortino Ratio Rank: 95
OPEN Omega Ratio Rank: 91
OPEN Calmar Ratio Rank: 95
OPEN Martin Ratio Rank: 88

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ALXO vs. OPEN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ALX Oncology Holdings Inc. (ALXO) and Opendoor Technologies Inc. (OPEN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ALXO	OPEN	Difference
Sharpe ratio Return per unit of total volatility	1.89	2.28	-0.38
Sortino ratio Return per unit of downside risk	2.86	3.46	-0.60
Omega ratio Gain probability vs. loss probability	1.31	1.40	-0.09
Calmar ratio Return relative to maximum drawdown	4.08	5.71	-1.62
Martin ratio Return relative to average drawdown	8.57	9.41	-0.84
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ALXO vs. OPEN - Sharpe Ratio Comparison

The current ALXO Sharpe Ratio is 1.89, which is comparable to the OPEN Sharpe Ratio of 2.28. The chart below compares the historical Sharpe Ratios of ALXO and OPEN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ALXO	OPEN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.89	2.28	-0.38
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.52	-0.23	-0.29
Sharpe Ratio (All Time) Calculated using the full available price history	-0.38	-0.12	-0.27

Correlation

The correlation between ALXO and OPEN is 0.24, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ALXO vs. OPEN - Dividend Comparison

Neither ALXO nor OPEN has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

ALXO vs. OPEN - Drawdown Comparison

The maximum ALXO drawdown since its inception was -99.64%, roughly equal to the maximum OPEN drawdown of -98.57%. Use the drawdown chart below to compare losses from any high point for ALXO and OPEN.

Drawdown Indicators

	ALXO	OPEN	Difference
Max Drawdown Largest peak-to-trough decline	-99.64%	-98.57%	-1.07%
Max Drawdown (1Y) Largest decline over 1 year	-50.46%	-57.47%	+7.01%
Max Drawdown (5Y) Largest decline over 5 years	-99.50%	-97.93%	-1.57%
Current Drawdown Current decline from peak	-98.21%	-86.52%	-11.69%
Average Drawdown Average peak-to-trough decline	-78.54%	-74.23%	-4.31%
Ulcer Index Depth and duration of drawdowns from previous peaks	24.03%	34.84%	-10.81%

Volatility

ALXO vs. OPEN - Volatility Comparison

The current volatility for ALX Oncology Holdings Inc. (ALXO) is 18.66%, while Opendoor Technologies Inc. (OPEN) has a volatility of 21.42%. This indicates that ALXO experiences smaller price fluctuations and is considered to be less risky than OPEN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ALXO	OPEN	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.66%	21.42%	-2.76%
Volatility (6M) Calculated over the trailing 6-month period	73.93%	64.21%	+9.72%
Volatility (1Y) Calculated over the trailing 1-year period	118.14%	165.92%	-47.78%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	99.42%	113.89%	-14.47%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	99.22%	111.60%	-12.38%

Financials