ALXO vs. OPEN

Last updated Aug 1, 2026

ALXO (ALX Oncology Holdings Inc.) and OPEN (Opendoor Technologies Inc.) are both stocks. ALXO operates in Biotechnology (Healthcare), while OPEN operates in Real Estate - Services (Real Estate). Over the past 5 years, ALXO returned -49.41%/yr vs -23.45%/yr for OPEN. Their 0.23 correlation means their historical movements had little consistent relationship.

Performance

ALXO vs. OPEN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ALX Oncology Holdings Inc. (ALXO) and Opendoor Technologies Inc. (OPEN). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ALXO achieves a 71.68% return, which is significantly higher than OPEN's -35.33% return.

ALXO

• 1D: -0.51%
• 1M: -6.28%
• 6M: 11.49%
• YTD: 71.68%
• 1Y: 274.45%
• 3Y*: -31.21%
• 5Y*: -49.41%
• 10Y*: —
• ALL TIME*: -38.50%

OPEN

• 1D: -1.31%
• 1M: -23.06%
• 6M: -26.80%
• YTD: -35.33%
• 1Y: 85.51%
• 3Y*: -9.58%
• 5Y*: -23.45%
• 10Y*: —
• ALL TIME*: -15.55%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ALXO ALX Oncology Holdings Inc.	$1.10M	$1.73M	$2.41M
OPEN Opendoor Technologies Inc.	$222.57M	$351.20M	$257.92M

ALXO vs. OPEN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ALXO ALX Oncology Holdings Inc.	71.68%	-32.34%	-88.78%	32.12%	-47.56%	-75.07%	136.16%
OPEN Opendoor Technologies Inc.	-35.33%	276.52%	-64.29%	286.21%	-92.06%	-35.72%	89.42%

Correlation

The correlation between ALXO and OPEN is 0.09, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.09
Correlation (3Y) Balances recent behavior with more history.	0.16
Correlation (5Y) Shows whether the relationship held over a longer period.	0.24
Correlation (All Time) Calculated using the full available price history since Jul 17, 2020	0.23

The correlation between ALXO and OPEN shifts across timeframes, from 0.09 (1 year) to 0.24 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ALXO : $261.05M OPEN : $3.64B
EPS ALXO : -$1.25 OPEN : -$1.69
PB Ratio ALXO : 1.34 OPEN : 3.79
Total Revenue (TTM) ALXO : $0.00 OPEN : $3.94B
Gross Profit (TTM) ALXO : $0.00 OPEN : $312.00M
EBITDA (TTM) ALXO : -$88.92M OPEN : -$1.25B

Return for Risk

ALXO vs. OPEN — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ALXO

ALXO Risk / Return Rank: 91
ALXO Sharpe Ratio Rank: 93
ALXO Sortino Ratio Rank: 91
ALXO Omega Ratio Rank: 87
ALXO Calmar Ratio Rank: 95
ALXO Martin Ratio Rank: 89

OPEN

OPEN Risk / Return Rank: 76
OPEN Sharpe Ratio Rank: 71
OPEN Sortino Ratio Rank: 85
OPEN Omega Ratio Rank: 80
OPEN Calmar Ratio Rank: 77
OPEN Martin Ratio Rank: 69

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ALXO vs. OPEN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ALX Oncology Holdings Inc. (ALXO) and Opendoor Technologies Inc. (OPEN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ALXO	OPEN	Difference
Sharpe ratio: Return per unit of total volatility	2.11	0.82	+1.29
Sortino ratio: Return per unit of downside risk	2.92	2.32	+0.60
Omega ratio: Gain probability vs. loss probability	1.33	1.26	+0.07
Calmar ratio: Return relative to maximum drawdown	4.83	1.76	+3.07
Martin ratio: Return relative to average drawdown	9.03	2.65	+6.38

ALXO vs. OPEN - Sharpe Ratio Comparison

The current ALXO Sharpe Ratio is 2.11, which is higher than the OPEN Sharpe Ratio of 0.82. The chart below compares the historical Sharpe Ratios of ALXO and OPEN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ALXO vs. OPEN - Drawdown Comparison

The maximum ALXO drawdown since its inception was -99.64%, roughly equal to the maximum OPEN drawdown of -98.57%. Use the drawdown chart below to compare losses from any high point for ALXO and OPEN.

Drawdown Indicators

	ALXO	OPEN	Difference
Max Drawdown Largest peak-to-trough decline	-99.64%	-98.57%	-1.07%
Max Drawdown (1Y) Largest decline over 1 year	-50.46%	-63.95%	+13.49%
Max Drawdown (3Y) Largest decline over 3 years	-97.69%	-89.15%	-8.54%
Max Drawdown (5Y) Largest decline over 5 years	-99.50%	-97.93%	-1.57%
Current Drawdown Current decline from peak	-98.27%	-89.14%	-9.13%
Average Drawdown Average peak-to-trough decline	-79.69%	-74.85%	-4.84%
Ulcer Index Depth and duration of drawdowns from previous peaks	26.91%	42.32%	-15.41%

Volatility

ALXO vs. OPEN - Volatility Comparison

The current volatility for ALX Oncology Holdings Inc. (ALXO) is 21.75%, while Opendoor Technologies Inc. (OPEN) has a volatility of 24.21%. This indicates that ALXO experiences smaller price fluctuations and is considered to be less risky than OPEN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ALXO	OPEN	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.75%	24.21%	-2.46%
Volatility (6M) Calculated over the trailing 6-month period	58.88%	51.37%	+7.51%
Volatility (1Y) Calculated over the trailing 1-year period	115.83%	137.74%	-21.91%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	100.05%	113.92%	-13.87%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	98.51%	109.64%	-11.13%

Dividends

ALXO vs. OPEN - Dividend Comparison

Neither ALXO nor OPEN has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ALXO and OPEN in my portfolio?

ALXO and OPEN have a correlation of 0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ALXO or OPEN?

OPEN has higher volatility (24.21%) compared to ALXO (21.75%). In terms of maximum drawdown, ALXO dropped -99.64% vs OPEN's -98.57%.

Which has better risk-adjusted returns?

ALXO currently has the higher Sharpe Ratio (2.10 vs 0.82), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.