ABVX vs. AZN

Last updated Jun 4, 2026

ABVX (Abivax SA American Depositary Shares) and AZN (AstraZeneca PLC) are both stocks. Both are in the Healthcare sector — ABVX in Biotechnology, AZN in Drug Manufacturers - General. Over the past year, ABVX returned 1064.73% vs 26.16% for AZN. At a 0.20 correlation, their price movements are largely independent.

Performance

ABVX vs. AZN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Abivax SA American Depositary Shares (ABVX) and AstraZeneca PLC (AZN). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ABVX achieves a -33.15% return, which is significantly lower than AZN's -2.12% return.

ABVX

• 1D: 24.34%
• 1M: -23.03%
• YTD: -33.15%
• 6M: -18.73%
• 1Y: 1,064.73%
• 3Y*: —
• 5Y*: —
• 10Y*: —

AZN

• 1D: -0.66%
• 1M: -3.91%
• YTD: -2.12%
• 6M: -0.95%
• 1Y: 26.16%
• 3Y*: 9.19%
• 5Y*: 11.73%
• 10Y*: 14.81%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ABVX vs. AZN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
ABVX Abivax SA American Depositary Shares	-33.15%	1,742.28%	-31.59%	28.92%
AZN AstraZeneca PLC	-2.12%	43.30%	-0.62%	5.51%

Correlation

The correlation between ABVX and AZN is 0.30, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.30
Correlation (All Time) Calculated using the full available price history since Oct 23, 2023	0.20

The correlation between ABVX and AZN shifts across timeframes, from 0.20 (all time) to 0.30 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ABVX : $6.27B AZN : $275.17B
EPS ABVX : -$6.89 AZN : $6.66
PS Ratio ABVX : 555.24 AZN : 4.55
PB Ratio ABVX : 13.78 AZN : 5.81
Total Revenue (TTM) ABVX : $10.79M AZN : $60.44B
Gross Profit (TTM) ABVX : $9.76M AZN : $49.37B
EBITDA (TTM) ABVX : -$411.59M AZN : $20.47B

Return for Risk

ABVX vs. AZN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ABVX

ABVX Risk / Return Rank: 97
ABVX Sharpe Ratio Rank: 86
ABVX Sortino Ratio Rank: 100
ABVX Omega Ratio Rank: 99
ABVX Calmar Ratio Rank: 99
ABVX Martin Ratio Rank: 100

AZN

AZN Risk / Return Rank: 70
AZN Sharpe Ratio Rank: 72
AZN Sortino Ratio Rank: 70
AZN Omega Ratio Rank: 65
AZN Calmar Ratio Rank: 71
AZN Martin Ratio Rank: 74

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ABVX vs. AZN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Abivax SA American Depositary Shares (ABVX) and AstraZeneca PLC (AZN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ABVX	AZN	Difference
Sharpe ratio: Return per unit of total volatility	1.82	1.05	+0.77
Sortino ratio: Return per unit of downside risk	12.16	1.75	+10.42
Omega ratio: Gain probability vs. loss probability	3.08	1.20	+1.88
Calmar ratio: Return relative to maximum drawdown	21.48	1.71	+19.77
Martin ratio: Return relative to average drawdown	77.84	4.70	+73.15
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ABVX vs. AZN - Sharpe Ratio Comparison

The current ABVX Sharpe Ratio is 1.82, which is higher than the AZN Sharpe Ratio of 1.05. The chart below compares the historical Sharpe Ratios of ABVX and AZN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ABVX	AZN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.82	1.05	+0.77
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.49	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.60	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.41	0.49	-0.08

Drawdowns

ABVX vs. AZN - Drawdown Comparison

The maximum ABVX drawdown since its inception was -67.46%, which is greater than AZN's maximum drawdown of -48.94%. Use the drawdown chart below to compare losses from any high point for ABVX and AZN.

Drawdown Indicators

	ABVX	AZN	Difference
Max Drawdown Largest peak-to-trough decline	-67.46%	-48.94%	-18.52%
Max Drawdown (1Y) Largest decline over 1 year	-50.11%	-15.43%	-34.68%
Max Drawdown (3Y) Largest decline over 3 years	—	-27.87%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-27.87%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-27.87%	—
Current Drawdown Current decline from peak	-37.96%	-15.43%	-22.53%
Average Drawdown Average peak-to-trough decline	-23.60%	-11.37%	-12.23%
Ulcer Index Depth and duration of drawdowns from previous peaks	13.80%	5.60%	+8.20%

Volatility

ABVX vs. AZN - Volatility Comparison

Abivax SA American Depositary Shares (ABVX) has a higher volatility of 64.55% compared to AstraZeneca PLC (AZN) at 6.36%. This indicates that ABVX's price experiences larger fluctuations and is considered to be riskier than AZN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ABVX	AZN	Difference
Volatility (1M) Calculated over the trailing 1-month period	64.55%	6.36%	+58.19%
Volatility (6M) Calculated over the trailing 6-month period	75.86%	17.06%	+58.80%
Volatility (1Y) Calculated over the trailing 1-year period	590.92%	25.18%	+565.74%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	369.01%	23.94%	+345.07%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	369.01%	24.90%	+344.11%

Dividends

ABVX vs. AZN - Dividend Comparison

ABVX has not paid dividends to shareholders, while AZN's dividend yield for the trailing twelve months is around 3.02%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ABVX Abivax SA American Depositary Shares	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
AZN AstraZeneca PLC	3.02%	1.70%	2.27%	2.15%	2.12%	2.35%	2.80%	2.81%	3.69%	3.95%	5.01%	4.06%

Financials

Frequently Asked Questions

Can I hold both ABVX and AZN in my portfolio?

ABVX and AZN have a correlation of 0.30, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ABVX or AZN?

ABVX has higher volatility (64.55%) compared to AZN (6.36%). In terms of maximum drawdown, ABVX dropped -67.46% vs AZN's -48.94%.

Which has better risk-adjusted returns?

ABVX currently has the higher Sharpe Ratio (1.82 vs 1.05), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.