2B78.DE vs. ZPDH.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and ZPDH.DE (SPDR S&P US Health Care Select Sector UCITS ETF) are both Health & Biotech Equities funds - 2B78.DE tracks the iSTOXX® FactSet Breakthrough Healthcare while ZPDH.DE tracks the S&P Health Care Select Sector. Both are passively managed. Over the past 5 years, 2B78.DE returned -1.74%/yr vs 6.73%/yr for ZPDH.DE. A 0.69 correlation means they provide meaningful diversification when combined. 2B78.DE charges 0.40%/yr vs 0.15%/yr for ZPDH.DE.
Performance
2B78.DE vs. ZPDH.DE - Performance Comparison
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Returns By Period
In the year-to-date period, 2B78.DE achieves a -2.07% return, which is significantly lower than ZPDH.DE's -1.12% return.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
ZPDH.DE
- 1D
- 2.83%
- 1M
- 5.48%
- YTD
- -1.12%
- 6M
- -0.21%
- 1Y
- 13.04%
- 3Y*
- 3.67%
- 5Y*
- 6.73%
- 10Y*
- 8.92%
2B78.DE vs. ZPDH.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 38.75% | 16.74% | 0.39% | 19.45% |
ZPDH.DE SPDR S&P US Health Care Select Sector UCITS ETF | -1.12% | 1.73% | 8.46% | -1.73% | 3.31% | 37.77% | 1.69% | 24.37% | 9.07% | 6.98% |
Correlation
The correlation between 2B78.DE and ZPDH.DE is 0.70, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.70 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.65 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.64 |
Correlation (All Time) Calculated using the full available price history since Sep 14, 2016 | 0.69 |
The correlation between 2B78.DE and ZPDH.DE has been stable across timeframes, ranging from 0.64 to 0.70 - a consistent structural relationship.
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Return for Risk
2B78.DE vs. ZPDH.DE — Risk / Return Rank
2B78.DE
ZPDH.DE
2B78.DE vs. ZPDH.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and SPDR S&P US Health Care Select Sector UCITS ETF (ZPDH.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | ZPDH.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.07 | ||
| Sortino ratioReturn per unit of downside risk | +0.03 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.16 | +0.01 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 1.21 | +0.03 |
| Martin ratioReturn relative to average drawdown | 3.07 | 2.95 | +0.12 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | ZPDH.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 0.89 | +0.07 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | 0.46 | -0.56 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.56 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | 0.46 | -0.15 |
Drawdowns
2B78.DE vs. ZPDH.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, which is greater than ZPDH.DE's maximum drawdown of -26.61%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and ZPDH.DE.
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Drawdown Indicators
| 2B78.DE | ZPDH.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -26.61% | -11.97% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -10.77% | -1.28% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -22.64% | -2.68% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | -22.64% | -14.35% |
Max Drawdown (10Y)Largest decline over 10 years | — | -26.61% | — |
Current DrawdownCurrent decline from peak | -19.03% | -7.28% | -11.75% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -5.80% | -8.56% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 4.41% | +0.45% |
Volatility
2B78.DE vs. ZPDH.DE - Volatility Comparison
The current volatility for iShares Healthcare Innovation UCITS ETF (2B78.DE) is 3.74%, while SPDR S&P US Health Care Select Sector UCITS ETF (ZPDH.DE) has a volatility of 5.13%. This indicates that 2B78.DE experiences smaller price fluctuations and is considered to be less risky than ZPDH.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | ZPDH.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 5.13% | -1.39% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 10.16% | +0.81% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 14.63% | +1.04% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 14.47% | +3.44% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 15.77% | +3.02% |
2B78.DE vs. ZPDH.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is higher than ZPDH.DE's 0.15% expense ratio.
Dividends
2B78.DE vs. ZPDH.DE - Dividend Comparison
Neither 2B78.DE nor ZPDH.DE has paid dividends to shareholders.
Frequently Asked Questions
2B78.DE and ZPDH.DE have a correlation of 0.70, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, ZPDH.DE is cheaper at 0.15% per year. The better choice depends on whether you care most about return, fees, risk, or income.
ZPDH.DE is cheaper with a 0.15% expense ratio, compared with 0.40% for 2B78.DE.
2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while ZPDH.DE tracks S&P Health Care Select Sector. They also come from different issuers: iShares and State Street. Their fees differ too: 0.40% for 2B78.DE and 0.15% for ZPDH.DE.
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