2B78.DE vs. ISPA.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and ISPA.DE (iShares STOXX Global Select Dividend 100 UCITS ETF (DE)) are both exchange-traded funds - 2B78.DE is a Health & Biotech Equities fund tracking the iSTOXX® FactSet Breakthrough Healthcare, while ISPA.DE is a Global Equities fund tracking the STOXX® Global Select Dividend 100 index. Both are passively managed. Over the past 5 years, 2B78.DE returned -1.74%/yr vs 11.00%/yr for ISPA.DE. A 0.54 correlation means they provide meaningful diversification when combined. 2B78.DE charges 0.40%/yr vs 0.46%/yr for ISPA.DE.
Performance
2B78.DE vs. ISPA.DE - Performance Comparison
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Returns By Period
In the year-to-date period, 2B78.DE achieves a -2.07% return, which is significantly lower than ISPA.DE's 13.48% return.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
ISPA.DE
- 1D
- 0.49%
- 1M
- 1.28%
- YTD
- 13.48%
- 6M
- 15.35%
- 1Y
- 29.45%
- 3Y*
- 18.65%
- 5Y*
- 11.00%
- 10Y*
- 8.98%
2B78.DE vs. ISPA.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 38.75% | 16.74% | 0.39% | 19.45% |
ISPA.DE iShares STOXX Global Select Dividend 100 UCITS ETF (DE) | 13.48% | 19.72% | 12.97% | 4.80% | 0.43% | 22.39% | -9.12% | 24.24% | -7.51% | 2.97% |
Correlation
The correlation between 2B78.DE and ISPA.DE is 0.48, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.48 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.52 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.50 |
Correlation (All Time) Calculated using the full available price history since Sep 14, 2016 | 0.54 |
The correlation between 2B78.DE and ISPA.DE has been stable across timeframes, ranging from 0.48 to 0.54 - a consistent structural relationship.
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Return for Risk
2B78.DE vs. ISPA.DE — Risk / Return Rank
2B78.DE
ISPA.DE
2B78.DE vs. ISPA.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and iShares STOXX Global Select Dividend 100 UCITS ETF (DE) (ISPA.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | ISPA.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.40 | ||
| Sortino ratioReturn per unit of downside risk | -3.22 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.62 | -0.45 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 8.10 | -6.86 |
| Martin ratioReturn relative to average drawdown | 3.07 | 28.73 | -25.66 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | ISPA.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 3.35 | -2.40 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | 0.91 | -1.00 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.60 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | 0.68 | -0.37 |
Drawdowns
2B78.DE vs. ISPA.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, roughly equal to the maximum ISPA.DE drawdown of -38.91%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and ISPA.DE.
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Drawdown Indicators
| 2B78.DE | ISPA.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -38.91% | +0.33% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -3.63% | -8.42% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -15.10% | -10.22% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | -15.10% | -21.89% |
Max Drawdown (10Y)Largest decline over 10 years | — | -38.91% | — |
Current DrawdownCurrent decline from peak | -19.03% | -1.09% | -17.94% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -4.46% | -9.90% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 1.03% | +3.83% |
Volatility
2B78.DE vs. ISPA.DE - Volatility Comparison
iShares Healthcare Innovation UCITS ETF (2B78.DE) has a higher volatility of 3.74% compared to iShares STOXX Global Select Dividend 100 UCITS ETF (DE) (ISPA.DE) at 2.62%. This indicates that 2B78.DE's price experiences larger fluctuations and is considered to be riskier than ISPA.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | ISPA.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 2.62% | +1.12% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 6.51% | +4.46% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 8.77% | +6.90% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 12.00% | +5.91% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 14.79% | +4.00% |
2B78.DE vs. ISPA.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is lower than ISPA.DE's 0.46% expense ratio.
Dividends
2B78.DE vs. ISPA.DE - Dividend Comparison
2B78.DE has not paid dividends to shareholders, while ISPA.DE's dividend yield for the trailing twelve months is around 3.75%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
ISPA.DE iShares STOXX Global Select Dividend 100 UCITS ETF (DE) | 3.75% | 4.52% | 4.89% | 5.91% | 6.92% | 3.32% | 4.04% | 4.02% | 3.37% | 5.66% | 3.64% | 4.35% |
Frequently Asked Questions
2B78.DE and ISPA.DE have a correlation of 0.48, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, 2B78.DE is cheaper at 0.40% per year. The better choice depends on whether you care most about return, fees, risk, or income.
2B78.DE is cheaper with a 0.40% expense ratio, compared with 0.46% for ISPA.DE.
2B78.DE is categorized as Health & Biotech Equities, while ISPA.DE is Global Equities. 2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while ISPA.DE tracks STOXX® Global Select Dividend 100 index. Their fees differ too: 0.40% for 2B78.DE and 0.46% for ISPA.DE.
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